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The origin of mammalian network of lymphatic vessels

Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculature - the network of vessels and capillaries critical to various essential housekeeping functions in the body.

4 Oct 2007

PAZAR - virtual bazaar of gene regulation data

An international team has opened a virtual bazaar, called PAZAR, which allows biologists to share information about gene regulation through individually managed 'boutiques' (data collections).

4 Oct 2007

Molecular basis of the cyanide polymorphism

That clover necklace you make for your child could well be a ring of poison.

2 Oct 2007

Scientists study folding of the brain's cortex

Engineers at Washington University in St. Louis are finding common ground between the shaping of the brain and the heart during embryonic development.

2 Oct 2007

Protein architectures provide window on the history of life

The present can tell you a lot about the past, but you need to know where to look.

2 Oct 2007

Origin of the mammalian lymphatic vasculature

In the October 1 issue of G&D, Dr. Guillermo Oliver (St. Jude Children's Research Hospital) and colleagues present new evidence to resolve a century-old debate over the origin of the mammalian lymphatic vasculature.

1 Oct 2007

Feeding the world without genetic engineering

The work of a Kansas State University professor is challenging the assumption that genetically engineered plants are the great scientific and technological revolution in agriculture and the only efficient and cheap way to feed a growing population.

1 Oct 2007

Scientists perform computer simulation that shows how proteins vibrate in a crystal

An international collaboration directed by an Oak Ridge National Laboratory researcher has performed the first-ever atomic-detail computer simulation of how proteins vibrate in a crystal.

27 Sep 2007

New view of what causes greatest genetic variability among individuals

A study by Yale researchers offers a new view of what causes the greatest genetic variability among individuals - suggesting that it is due less to single point mutations than to the presence of structural changes that cause extended segments of the human genome to be missing, rearranged, or present in extra copies.

27 Sep 2007

Genetic sequence of Giardia complete

Giardia lamblia, one of the most common human parasites in the United States, causes more than 20,000 intestinal infections a year, often through contact with contaminated drinking or swimming water.

27 Sep 2007

Tumor cell receptor provides new therapeutic target

Working with a line of highly metastatic head and neck cancer cells, a research team at the Winship Cancer Institute and Emory University School of Medicine has found that a specific cell surface receptor present at very low levels in non-metastatic head and neck cancer cells.

27 Sep 2007

Evaluation of poly(glycerol adipate) nanoparticle uptake in an in vitro 3-D brain tumor co-culture model

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists.

27 Sep 2007

In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles

Most people think of hydrogen peroxide as a topical germ killer, but the medicine cabinet staple is gaining steam in the medical community as an early indicator of disease in the body.

27 Sep 2007

MicroPET-based biodistribution of quantum dots in living mice

A wide variety of experiments have shown that nanoscale quantum dots have the potential to detect early-stage cancer and even monitor the progress of anticancer therapies.

27 Sep 2007

Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery

In the quest to turn carbon nanotubes from nanoscale wonder into clinically useful drug and imaging agent delivery agents, researchers have often added polymer coatings to the outside of the nanotubes in order to render them biocompatible.

27 Sep 2007

Gold nanorods coated with multilayer polyelectrolyte as contrast agents for multimodal imaging

A growing body of research has demonstrated that gold nanorods can serve as extremely bright imaging agents.

27 Sep 2007

Organically modified silica nanoparticles with covalently incorporated photosensitizer for photodynamic therapy of cancer

Photodynamic therapy, in which light activates a chemical known as a photosensitizer, triggering the production of cell-killing reactive oxygen, has proven itself as an effective therapy for a limited number of cancers.

27 Sep 2007