Medical Science News

RSS

Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma

Nanoscale, inorganic fluorescent imaging agents such as quantum dots have become an important tool for researchers studying key biomolecules involved in cancer.

18 Dec 2006

FeCo/graphitic-shell nanocrystals as advanced magnetic-resonance-imaging and near-infrared agents

Alloys of iron and cobalt generate powerful magnetic signals that could be useful in nanoparticles designed to detect tumors using magnetic resonance imaging (MRI).

18 Dec 2006

Vascular targeted nanoparticles for imaging and treatment of brain tumors

Combining two promising approaches to diagnosing and treating cancer, a multidisciplinary research team at the University of Michigan has created a targeted multifunctional polymer nanoparticle that successfully images and kills brain tumors in laboratory animals.

4 Dec 2006

Biofunctional organic nanocrystals for quantitative detection of pathogen deoxyribonucleic acid

Waiting a day or more to get lab results back from the doctor's office soon could become a thing of a past.

4 Dec 2006

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

In attempt to identify biological markers, or biomarkers, that can signal the presence of cancer and help oncologists determine the best course of therapy when cancer is present, teams of investigators are scouring stored tissue samples obtained from thousands of cancer patients.

4 Dec 2006

Computational model for cancer invasion

Vito Quaranta clicks on a small black dot on his computer screen. The dot - which represents about a thousand cancer cells - begins to "grow," morphing into a mass with finger-like projections that looks like an invasive tumor.

2 Dec 2006

Genetically engineered blood protein can be used to split water into oxygen and hydrogen

Scientists have combined two molecules that occur naturally in blood to engineer a molecular complex that uses solar energy to split water into hydrogen and oxygen, says research published in the Journal of the American Chemical Society.

2 Dec 2006

Test strips for the rapid detection of cocaine

Saving the life of a poisoning victim is often a matter of minutes. It is best when the emergency doctor can perform a reliable diagnosis on the spot to determine which poison or what type of drug overdose a patient is suffering from. Complicated laboratory analyses and a complex apparatus are out of place in the emergency room.

21 Nov 2006

Nanotechnology continues to advance anticancer gene therapy

Given that cancer is a disease in which genetic errors play a major role, it should come as no surprise that many experts envision a time when gene therapy will play an equally important role in the treatment of cancer.

20 Nov 2006

Low-field magnetic separation of monodisperse Fe3O4 nanocrystals

Whether the goal is to separate different types of cells or molecules, methods that rely on the age-old principle of magnetism are a staple among researchers.

20 Nov 2006

Templated self-assembly of quantum dots from aqueous solution using protein scaffolds

Quantum dots are rapidly becoming biomedical researchers' tool of choice for adding a fluorescent label to a wide variety of biomolecules.

20 Nov 2006

Scientists discover function for antisense RNA

Researchers have found that a class of RNA molecules, previously thought to have no function, may in fact protect sex cells from self-destructing. These findings will be published in the November 17 issue of the journal Cell.

20 Nov 2006

Optical amplification of photothermal therapy with gold nanoparticles and nanoclusters

Gold nanoparticles, through their unique ability to convert light into heat, show great promise as miniature heaters capable of cooking cancer cells to death.

13 Nov 2006

Modified silicon-based surfaces provide good home to proteins

Silicon, whether in its elemental form as silicon wafers or in its oxidized form, known as silicon dioxide or silica, is proving to be a valuable material for biomedical nanotechnology, in large part because of the biocompatibility and chemical inertness of these substances.

13 Nov 2006

Polymer coating improves tumor-targeting nanoparticles

Adding a thin coating of the biocompatible polymer poly(ethylene glycol) (PEG) to the surface of sulfur-modified, or thiolated, nanoparticles designed to fall apart inside tumors, prolongs the time that the resulting nanoparticles remain in tumors.

13 Nov 2006

A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas

In a dramatic demonstration of the power of nanotechnology, a team of investigators has designed a nanoscale, polymeric drug delivery vehicle that when loaded with a widely used anticancer agent cures colon cancer in mice with a single dose.

13 Nov 2006

Nanoparticle probes with surface enhanced Raman spectroscopic tags for cellular cancer targeting

Cancer biologists are always on the lookout for new methods of studying the effects that drug therapy has on malignant cells.

6 Nov 2006

Nanoparticles for two-photon photodynamic therapy in living cells

Photodynamic therapy (PDT) uses a combination of ultraviolet or visible light and a light-sensitive chemical, or photosensitizer, to kill cancer cells using reactive oxygen.

6 Nov 2006

Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems

In an attempt to create a single device that can image and treat tumors simultaneously, researchers at the University of Texas Southwestern Medical Center at Dallas have successfully melded magnetic iron nanoparticles, the anticancer drug doxorubicin, and a polymer tagged with a tumor-targeted molecule into a stable nanoparticle that accumulates inside human tumor cells.

6 Nov 2006

Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery

Though researchers have made substantial progress in developing drug-ferrying nanoparticles that successfully target tumor cells in living animals, including humans, investigators have only now started the detailed work needed to identify formulation parameters that would optimize drug delivery to malignant cells.

6 Nov 2006

Medical Science News

Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma

FeCo/graphitic-shell nanocrystals as advanced magnetic-resonance-imaging and near-infrared agents

Vascular targeted nanoparticles for imaging and treatment of brain tumors

Biofunctional organic nanocrystals for quantitative detection of pathogen deoxyribonucleic acid

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

Computational model for cancer invasion

Genetically engineered blood protein can be used to split water into oxygen and hydrogen

Test strips for the rapid detection of cocaine

Nanotechnology continues to advance anticancer gene therapy

Low-field magnetic separation of monodisperse Fe3O4 nanocrystals

Templated self-assembly of quantum dots from aqueous solution using protein scaffolds

Scientists discover function for antisense RNA

Optical amplification of photothermal therapy with gold nanoparticles and nanoclusters

Modified silicon-based surfaces provide good home to proteins

Polymer coating improves tumor-targeting nanoparticles

A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas

Nanoparticle probes with surface enhanced Raman spectroscopic tags for cellular cancer targeting

Nanoparticles for two-photon photodynamic therapy in living cells

Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems

Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Latest News