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Small molecule drug shows promise as potential new treatment for multiple sclerosis

CAMH-led pre-clinical studies using a small molecule drug have shown promise as a potential new treatment for multiple sclerosis (MS). The results have been published today in the journal Science Advances.

8 Dec 2023

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

It only takes holding your breath for slightly too long to understand that too little oxygen is bad for you. But can you also have too much? Indeed, breathing air with a higher oxygen level than your body needs can cause health problems or even death.

8 Dec 2023

Exploring the role of liquid biopsies in early-stage prostate cancer

A new research perspective was published in Oncoscience (Volume 10) on November 30, 2023, entitled, "Evolving insights in blood-based liquid biopsies for prostate cancer interrogation."

8 Dec 2023

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues.

8 Dec 2023

VUB researchers develop a nanobody-based technology to prevent liver inflammation

Mathieu Vinken, a professor in the In Vitro Toxicology and Dermato-cosmetology (IVTD) lab at the Vrije Universiteit Brussel, and doctoral student Raf Van Campenhout have developed a technique based on nanobody technology to prevent liver inflammation.

8 Dec 2023

MIT engineers develop new bio-robotic model of the heart's right ventricle

MIT engineers have developed a robotic replica of the heart's right ventricle, which mimics the beating and blood-pumping action of live hearts.

8 Dec 2023

New VR goggles for mice provide more immersive experiences for lab research

Northwestern University researchers have developed new virtual reality (VR) goggles for mice.

8 Dec 2023

Plant-based diets and genetic risk for obesity

The potential link between plant-based dietary patterns (plant-based dietary indices, PDI) and genetic risk of obesity.

8 Dec 2023

How did machine learning models perform in identifying hepatitis in patients with diabetes?

The performance of different machine learning models in detecting hepatitis among people with diabetes.

8 Dec 2023

Study identifies new target for fatty liver disease treatment

The global rise in obesity and diabetes is leading to an epidemic in fatty liver disease affecting 20-30 per cent of the world's population.

7 Dec 2023

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Study published in Nature Immunology reveals that repeated mRNA COVID-19 vaccinations enhance immune response, especially in previously infected individuals, leading to a diversified and increased number of immune cell clones and a stronger ability to combat various virus strains.

7 Dec 2023

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Study presents a genome-wide map, "Gnocchi," constructed from 76,156 human genomes, revealing that non-coding regions rich in regulatory elements are crucial in understanding human traits and diseases.

7 Dec 2023

Is your body out of sync? Study finds organs age at varying rates

Research uncovers that human organs age at varying rates, with some showing accelerated aging compared to chronological age, significantly impacting overall health and disease risk. The study used advanced blood plasma proteomics to analyze organ-specific aging in nearly 5,700 adults, linking it to increased risks of heart failure and Alzheimer's disease.

7 Dec 2023

Flaxseed lignans found to influence gut microbiome and breast cancer risk

A new study demonstrates that the human gut microbiome may be a factor in breast health. Lifestyle and diet have long been known to affect human health.

7 Dec 2023

Liver trigger holds the key to boosting gene therapy success

Indiana University School of Medicine researchers have uncovered vital insights regarding a liver trigger that blocks an undesired immune response from gene therapy, surprisingly resulting in the activation of specific immune cells, despite the liver's typical role in suppressing immune responses.

7 Dec 2023

Large language models enhance differential diagnosis, paving the way for AI-assisted medical decision-making

Study explores optimizing large language models (LLMs) for differential diagnosis (DDx), demonstrating their potential in assisting clinicians with accurate disease diagnosis using real-world medical cases.

7 Dec 2023

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Study explores immunoregulatory nanomedicines for respiratory infections, highlighting their potential in enhancing treatment outcomes and vaccine efficacy.

7 Dec 2023

Novel stem cell treatment could revolutionize liver disease management

Mortality related to end stage liver disease is ranked as the 12th most common cause of death in the U.S. Liver transplantation remains the only treatment for end stage liver disease, but there is a critical shortage of organ donors, necessitating a dire need for new forms of treatment.

7 Dec 2023

Study offers new insights into the brain's inhibitory control mechanisms

Published in the 2023 Volume 3 issue of Psychoradiology a team of dedicated researchers from The University of Hong Kong and The University of Electronic Science and Technology of China has conclusively identified the right inferior frontal gyrus (rIFG) as a key input and causal regulator within the subcortical response inhibition nodes.

7 Dec 2023

Researchers discover how bexmarilimab activates immune cells against tumors

Researchers at the University of Turku, Finland, have uncovered how the new bexmarilimab therapy alters the function of immune cells so that they can infiltrate the tumor in cancer patients who do not respond to any other current therapies.

7 Dec 2023

Medical Science News

Small molecule drug shows promise as potential new treatment for multiple sclerosis

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

Exploring the role of liquid biopsies in early-stage prostate cancer

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

VUB researchers develop a nanobody-based technology to prevent liver inflammation

MIT engineers develop new bio-robotic model of the heart's right ventricle

New VR goggles for mice provide more immersive experiences for lab research

Plant-based diets and genetic risk for obesity

How did machine learning models perform in identifying hepatitis in patients with diabetes?

Study identifies new target for fatty liver disease treatment

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Is your body out of sync? Study finds organs age at varying rates

Flaxseed lignans found to influence gut microbiome and breast cancer risk

Liver trigger holds the key to boosting gene therapy success

Large language models enhance differential diagnosis, paving the way for AI-assisted medical decision-making

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Novel stem cell treatment could revolutionize liver disease management

Study offers new insights into the brain's inhibitory control mechanisms

Researchers discover how bexmarilimab activates immune cells against tumors

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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