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New mechanism of immune evasion discovered in cancer cells

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

11 Feb 2025

Novel biomarker for early prevention of Alzheimer’s disease

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering potential for timely intervention.

11 Feb 2025

Single dose of antibody shields macaques from severe H5N1 influenza

National Institutes of Health (NIH) scientists and their colleagues report that a single dose of a broadly neutralizing antibody (bnAb) administered prior to virus exposure protects macaques from severe H5N1 avian influenza.

11 Feb 2025

Advances in the design and synthesis of isosteviol derivatives

Announcing a new publication for Acta Materia Medica journal. Isosteviol and its derivatives, diterpene compounds with a wide range of biological activities, play important antiviral, antibacterial, antioxidant, antitumor, analgesic, anti-inflammatory, antipyretic, antifungal, and anticardiovascular disease roles.

11 Feb 2025

Adverse pregnancy outcomes increase cardiovascular risk, even in unaffected sisters

A study reveals that women with adverse pregnancy outcomes and their APO-free sisters share elevated cardiovascular disease risks, indicating genetic links.

11 Feb 2025

Trust and risk perception influence brain activity in health assessments

Perceiving whether another person is a personal health risk requires quickly assessing their trustworthiness.

11 Feb 2025

Daily fruit and vegetable extracts may boost brain power

A study reveals polyphenol-rich nutraceuticals enhance cognitive performance and boost neuroprotective biomarkers, offering a dietary approach to brain health.

11 Feb 2025

Light-activated therapy reduces antibiotic resistance in Staphylococcus aureus

Photodynamic inactivation using curcumin shows promise in reducing antibiotic resistance diversity in Staphylococcus aureus, enhancing treatment effectiveness.

11 Feb 2025

Adrenomedullin hormone as key driver of insulin resistance in obesity-linked type 2 diabetes

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

11 Feb 2025

Mental health drives med student dropout rate

Around 1 in 5 UK medical students considers dropping out of medical school, with mental health issues a key contributor to their intention to abandon medicine, suggest the results of an observational study published in the open access journal BMJ Open.

11 Feb 2025

Persistent social and cognitive difficulties linked to poor GCSE results

The combination of poorly developed social and cognitive skills during childhood is linked to poor exam results by the age of 16, with those for whom these issues persist throughout their childhood more than 4 times as likely not to pass at least 5 GCSEs, finds research published online in the Archives of Disease in Childhood.

11 Feb 2025

PDZK1's role in estrogen-induced cholestasis unveiled

Announcing a new publication for Acta Materia Medica journal. Estrogens have been reported to cause dysfunction in biliary transport systems, thereby inducing cholestasis. Multidrug resistance-associated protein 2 (MRP2) is a transporter responsible for independent bile flow.

11 Feb 2025

Cerebral cortex plays key role in memory and novelty detection

The cerebral cortex is the largest part of a mammal's brain, and by some measures the most important. In humans in particular, it's where most things happen-like perception, thinking, memory storage and decision-making.

10 Feb 2025

Neuroscientists discover how the brain corrects visual distortions during movement

Why do our mental images stay sharp even when we are moving fast? A team of neuroscientists led by Professor Maximilian Jösch at the Institute of Science and Technology Austria (ISTA) has identified a mechanism that corrects visual distortions caused by movement in animals.

10 Feb 2025

Your gut bacteria shape your health from childhood to old age, study reveals

Researchers found that gut microbiome composition is strongly linked to metabolic health across different life stages, with greater effects seen in older adults.

10 Feb 2025

Breakthrough study identifies new way to address Alzheimer's at early stages

A team of researchers from the Keck School of Medicine of USC has unlocked the details of a cellular pathway that triggers cellular inflammation and aging and is linked to Alzheimer's disease, particularly among those who carry the APOE4 genetic risk.

10 Feb 2025

Influenza A virus changes shape to evade immune responses

Influenza A virus particles strategically adapt their shape-to become either spheres or larger filaments-to favor their ability to infect cells depending on environmental conditions, according to a new study from National Institutes of Health (NIH) scientists.

10 Feb 2025

High cholesterol diets increase heart attack risk in U.S. veterans, study warns

Higher dietary cholesterol intake is linked to an increased risk of myocardial infarction among U.S. veterans, reinforcing the need for heart-healthy dietary choices.

10 Feb 2025

Study finds cerebellar serotonin as a "brake" to alleviate anxiety

Understanding the neural circuits that drive anxiety may help researchers discover circuit-specific targets and therefore increase the precision of treatment strategies.

10 Feb 2025

Tick-borne encephalitis emerges in Britain: Experts urge vigilance

Tick-borne encephalitis virus (TBEV) has now been confirmed in locally acquired human cases in the U.K., with evidence of established transmission in British tick populations. Increased surveillance and clinician awareness are crucial to detecting and managing this emerging threat.

10 Feb 2025