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Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.

4 Jun 2023

Study offers the most comprehensive archive of cellular, molecular features involved in psoriatic disease

Beneath and beyond the reddish, flaky lesions that form in the skin of those with psoriasis, mild and severe forms of the disease can be told apart by the activity of key cells and signaling pathways, a new study shows.

2 Jun 2023

EULAR's new strategy for 2024 - 2028 announced

Over the period 2018 - 2023, EULAR, the leading organization in RMDs, has grown substantially and has been professionalized in every aspect.

2 Jun 2023

Immune system's ability to respond to spinal cord injuries diminishes with age, study suggests

New research suggests that the immune system's ability to respond to spinal cord injuries diminishes with age – and identifies potential avenues to improve that response and help patients heal.

2 Jun 2023

University of Louisville researchers receive $5.8 million to prevent immune system dysregulation

Researchers at the University of Louisville have received $5.8 million in two grants from the National Institutes of Health to expand their work to better understand and prevent immune system dysregulation responsible for acute respiratory distress, the condition responsible for serious illness and death in some COVID-19 patients.

2 Jun 2023

Lymphoid depletion associated with suppressed APC function characterizes the lethality of COVID-19 in mice

Individuals who are immunocompromised are considered at higher risk for severe or longer disease with COVID-19. Understanding the systemic immune response is vital for research efforts to reduce its effects on multiple organs.

2 Jun 2023

The mediation roles of parental role-modeling and food availability in the socioeconomic inequalities of children’s diet

Scientists explored how family socioeconomic status and parental role-modelling influence children's diet.

2 Jun 2023

Is there an association being plant-based diets and mental health?

Researchers determined the relationship between plant-origin diet indices and mental health disorders

2 Jun 2023

Physically active lessons may positively impact the cognitive performance of children

Researchers evaluated the effects of physically active lessons on cognitive performance.

2 Jun 2023

Evaluating the effects of dietary trends on reproductive outcomes

Researchers evaluated the effects of dietary trends on reproductive outcomes.

2 Jun 2023

Sleep-disordered breathing in cognitively unimpaired amyloid-positive individuals may exacerbate neurodegeneration in medial temporal lobe subregions

A new study investigated the link between SDB severity and the volume of medial temporal lobe (MTL) substructures. In addition, it also evaluated the association between SDB and MTL subregions volumes with episodic memory performance.

2 Jun 2023

Can machine learning predict BMI in early childhood using data from the first 1000 days of life?

Researchers used a machine learning (ML)-based approach to predict adulthood obesity.

2 Jun 2023

Do veterans with COVID-19 experience similar outcomes when hospitalized in Veterans Health Administration hospitals vs. community hospitals?

Researchers compared COVID-19-related deaths and re-admission rates in VHA vs. community hospitals.

2 Jun 2023

Mother-to-child transmission of SARS-CoV-2: evaluating the association between preventive measures and the risk of infection

Researchers evaluated the mother-to-infant transmission rates of SARS-CoV-2.

2 Jun 2023

Is having a new child associated with increased antidepressant treatment in men?

Study determines whether recent fatherhood was associated with increased antidepressant treatment.

2 Jun 2023

To what extent does prenatal folate status modify associations between early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure and birth outcomes?

Researchers evaluated the relationship between PFAS exposure during pregnancy and birth outcomes.

2 Jun 2023

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

Research presents an assembly-line approach using bacteriophage T4 components to construct artificial viral vectors (AVVs). These AVVs have the potential to revolutionize gene therapies and personalized medicine by enabling the efficient delivery of biomolecules for molecular repairs and genome remodeling.

1 Jun 2023

Medical Science News

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Study offers the most comprehensive archive of cellular, molecular features involved in psoriatic disease

EULAR's new strategy for 2024 - 2028 announced

Immune system's ability to respond to spinal cord injuries diminishes with age, study suggests

University of Louisville researchers receive $5.8 million to prevent immune system dysregulation

Lymphoid depletion associated with suppressed APC function characterizes the lethality of COVID-19 in mice

The mediation roles of parental role-modeling and food availability in the socioeconomic inequalities of children’s diet

Is there an association being plant-based diets and mental health?

Physically active lessons may positively impact the cognitive performance of children

Evaluating the effects of dietary trends on reproductive outcomes

Sleep-disordered breathing in cognitively unimpaired amyloid-positive individuals may exacerbate neurodegeneration in medial temporal lobe subregions

Can machine learning predict BMI in early childhood using data from the first 1000 days of life?

Do veterans with COVID-19 experience similar outcomes when hospitalized in Veterans Health Administration hospitals vs. community hospitals?

Mother-to-child transmission of SARS-CoV-2: evaluating the association between preventive measures and the risk of infection

Is having a new child associated with increased antidepressant treatment in men?

To what extent does prenatal folate status modify associations between early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure and birth outcomes?

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

NCI launches new initiative to test new drug combinations that target specific tumor alterations

Miniature video capsule shows capabilities like a traditional tube-based endoscopy

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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