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At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

A study into the use of an at-home test which uses saliva rather than blood to diagnose adrenal insufficiency, which has been developed by scientists at the University of Sheffield with funding from the National Institute for Health and Care Research, and tested in Sheffield endocrine patients at Sheffield Teaching Hospitals NHS Foundation Trust, is making a difference to the health of patients and could reduce time to diagnosis.

6 Jan 2023

CU researchers discover a new mechanism for slowing cardiac fibrosis

Researchers at the University of Colorado School of Medicine have discovered a new mechanism for slowing scarring of heart tissue - a process known as cardiac fibrosis.

6 Jan 2023

Hair follicle transplants can rejuvenate scars, study finds

In a new study involving three volunteers, skin scars began to behave more like uninjured skin after they were treated with hair follicle transplants.

6 Jan 2023

People with latent tuberculosis infection could be at a higher risk for cardiovascular disease

Newly published research from the University of Cincinnati finds that people with latent tuberculosis infection (LTBI) have more inflammation and could be at a higher risk for cardiovascular disease.

6 Jan 2023

Marine plankton samples can help study the connections between ocean pollution and rates of chronic illnesses

Using samples from an almost century-old, ongoing survey of marine plankton, researchers at University of California San Diego School of Medicine suggest that rising levels of manmade chemicals found in parts of the world's oceans might be used to monitor the impact of human activity on ecosystem health, and may one day be used to study the connections between ocean pollution and land-based rates of childhood and adult chronic illnesses.

6 Jan 2023

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

The most common type of liver cancer, hepatocellular carcinoma (HCC), is already the third leading cause of cancer-related deaths globally - and cases are on the rise, both in the U.S. and worldwide.

6 Jan 2023

Pan-vaccine antigen strategy confers protection against cross-clade SARS-CoV-2 variants, including vaccine-resistant Omicron variants

Researchers developed a novel pan-vaccine antigen (Span)-based subunit vaccine against COVID-19.

6 Jan 2023

SARS-CoV-2 Delta and Omicron transmission within educational settings in relation to community-based outbreaks and mitigation measures

Researchers assessed whether school closures during COVID-19 outbreaks prevented viral transmission in Australia.

6 Jan 2023

The association between commonly reported symptoms following SARS-CoV-2 infection and subjective well-being

Researchers evaluated the association between subjective well-being and post-COVID-19 symptoms.

6 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

Study shows XBB.1.5 exhibits a substantially higher hACE2-binding affinity compared to BQ.1.1 and XBB/XBB.1

Researchers investigated the reasons for the rapid advent of SARS-CoV-2 XBB.1.5, a sublineage of the Omicron recombinant mutant XBB in the USA.

6 Jan 2023

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV."

6 Jan 2023

The risk factors and outcomes of ARDS following infection with SARS-CoV-2 in a young adult population

Researchers evaluated the outcomes and identified risk factors associated with the development of ARDS after SARS-CoV-2 infections among young adults.

6 Jan 2023

Is appropriate initial empirical antimicrobial therapy associated with lower in-hospital mortality in patients with bloodstream infections?

Researchers estimated the association between the receipt of appropriate initial empirical antibiotic treatment and in-hospital death among individuals hospitalized with BSI (bloodstream infections).

6 Jan 2023

Fluctuations of mood do not interfere with confidence in decision-making, study says

Study assessed for the first time whether daily fluctuations in mood and related variables (such as stress or sleep) are coupled to fluctuations in metacognitive states (such as confidence or response vigor) and concluded that in the healthy adult population, fluctuations of mood do not interfere with confidence in decision-making.

5 Jan 2023

Study describes the variations in drug response across genetic subtypes of childhood leukemia

Scientists at St. Jude Children's Research Hospital are reporting the most comprehensive study to date describing the variations in drug response across different genetic subtypes of acute lymphoblastic leukemia (ALL).

5 Jan 2023

History of obesity produces changes in innate immunity and neuroinflammation

A history of obesity caused by a high-fat diet produces changes in innate immunity that can promote inflammatory disease – changes that persist even after weight loss and a return to normal metabolism, according to a new study in mice.

5 Jan 2023

Research findings open the door to new strategies for promoting muscle function during aging

Proven to protect against a wide array of diseases, exercise may be the most powerful anti-aging intervention known to science.

5 Jan 2023

Study details the “immunometabolic editing” mechanism of tumor evolution

A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses.

5 Jan 2023

Historic agreement to accelerate trials into vaccines for cancer and wider diseases

Trials into vaccines for cancer and wider diseases will accelerate after the government reached a historic agreement with a leading biopharmaceutical firm to bring revolutionary research to England.

5 Jan 2023

Medical Science News

At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

CU researchers discover a new mechanism for slowing cardiac fibrosis

Hair follicle transplants can rejuvenate scars, study finds

People with latent tuberculosis infection could be at a higher risk for cardiovascular disease

Marine plankton samples can help study the connections between ocean pollution and rates of chronic illnesses

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

Pan-vaccine antigen strategy confers protection against cross-clade SARS-CoV-2 variants, including vaccine-resistant Omicron variants

SARS-CoV-2 Delta and Omicron transmission within educational settings in relation to community-based outbreaks and mitigation measures

The association between commonly reported symptoms following SARS-CoV-2 infection and subjective well-being

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

Study shows XBB.1.5 exhibits a substantially higher hACE2-binding affinity compared to BQ.1.1 and XBB/XBB.1

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

The risk factors and outcomes of ARDS following infection with SARS-CoV-2 in a young adult population

Is appropriate initial empirical antimicrobial therapy associated with lower in-hospital mortality in patients with bloodstream infections?

Fluctuations of mood do not interfere with confidence in decision-making, study says

Study describes the variations in drug response across genetic subtypes of childhood leukemia

History of obesity produces changes in innate immunity and neuroinflammation

Research findings open the door to new strategies for promoting muscle function during aging

Study details the “immunometabolic editing” mechanism of tumor evolution

Historic agreement to accelerate trials into vaccines for cancer and wider diseases

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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