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Study describes the variations in drug response across genetic subtypes of childhood leukemia

Scientists at St. Jude Children's Research Hospital are reporting the most comprehensive study to date describing the variations in drug response across different genetic subtypes of acute lymphoblastic leukemia (ALL).

5 Jan 2023

History of obesity produces changes in innate immunity and neuroinflammation

A history of obesity caused by a high-fat diet produces changes in innate immunity that can promote inflammatory disease – changes that persist even after weight loss and a return to normal metabolism, according to a new study in mice.

5 Jan 2023

Research findings open the door to new strategies for promoting muscle function during aging

Proven to protect against a wide array of diseases, exercise may be the most powerful anti-aging intervention known to science.

5 Jan 2023

Study details the “immunometabolic editing” mechanism of tumor evolution

A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses.

5 Jan 2023

Historic agreement to accelerate trials into vaccines for cancer and wider diseases

Trials into vaccines for cancer and wider diseases will accelerate after the government reached a historic agreement with a leading biopharmaceutical firm to bring revolutionary research to England.

5 Jan 2023

Sugar appears to play a role in polycystic kidney disease, study finds

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

5 Jan 2023

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Somebody just coughed on you. On a plane. At a dinner party. In a supermarket line. If only there were a "morning after" nasal spray that could knock out respiratory viruses' ability to colonize your nose and throat.

5 Jan 2023

Latest discovery provides new understanding of the fundamental mechanics of the human brain

From the complexity of neural networks to basic biological functions and structures, the human brain only reluctantly reveals its secrets.

5 Jan 2023

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells in and around a tumor, called tumor-infiltrating lymphocytes (TILs), in predicting whether HER2-positive breast cancer responds to treatment.

5 Jan 2023

Intestinal bacteria in multiple sclerosis patients vary with disease activity, study finds

Multiple sclerosis patients do not have the same bacteria in their intestines as healthy people. There are also differences in the composition and function of the bacteria in the intestines of multiple sclerosis patients, depending on whether their illness is active, and whether they are in treatment.

5 Jan 2023

What is the role of SARS-CoV-2 non-structural protein 2 in repressing host antiviral immunity?

Researchers uncovered a novel mechanism that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses (CoVs) use to exploit host antiviral immune system to facilitate their replication.

5 Jan 2023

Does bimodal visual-olfactory training with patient-preferred scents improve olfaction in individuals with COVID-19 postviral olfactory loss?

Researchers investigated whether using patient-preferred scents and a bimodal method of visual-olfactory training is more effective than unimodal olfactory training using scents assigned by physicians in treating patients experiencing anosmia after COVID-19.

5 Jan 2023

What was the effect of the COVID-19 pandemic on the mental well-being of university students?

Researchers evaluated changes in the mental health status of university-attending students in France 15.0 months post-commencement of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.

5 Jan 2023

Are patients with a history of MIS-C at increased risk of adverse reactions from COVID-19 vaccination?

Researchers investigated the reactogenicity of the COVID-19 vaccine in pediatric patients with MIS-C.

5 Jan 2023

Wayne State researcher wins $1.7 million NIH award to understand and tackle cisplatin-induced ototoxicity

A Wayne State University researcher has received a $1.7 million, five-year award from the National Institute on Deafness and Other Communication Disorders of the National Institutes of Health for the study, "Targeting nitrative stress for treatment of cisplatin ototoxicity."

5 Jan 2023

SynGAP Research Fund awards $180,000 grant to the University of Edinburgh Medical School's Patrick Wild Centre & Centre for Discovery Brain Sciences

SynGAP Research Fund (SRF), a 501(c)(3) public charity whose mission is to improve the quality of life for SYNGAP1 patients through the research and development of treatments, therapies and support systems, along with SynGAP Research Fund UK, today announced they have awarded a $180,000 grant to the University of Edinburgh Medical School's Patrick Wild Centre & Centre for Discovery Brain Sciences to advance the science around gene transfer to correct SYNGAP1 haploinsufficiency.

5 Jan 2023

Seroprevalence study demonstrates vaccination could boost impaired humoral immunity against Omicron BQ.1.1 subvariant

Researchers conducted a multicenter, cross-sectional seroprevalence study in emergency departments of five hospitals in North Rhine-Westphalia, Germany, between August and September 2022. They assessed point seroprevalence and neutralization activity against Wu01, BA.4/5, and BQ.1.1.

5 Jan 2023

Medical Science News

Study describes the variations in drug response across genetic subtypes of childhood leukemia

History of obesity produces changes in innate immunity and neuroinflammation

Research findings open the door to new strategies for promoting muscle function during aging

Study details the “immunometabolic editing” mechanism of tumor evolution

Historic agreement to accelerate trials into vaccines for cancer and wider diseases

Sugar appears to play a role in polycystic kidney disease, study finds

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Latest discovery provides new understanding of the fundamental mechanics of the human brain

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Intestinal bacteria in multiple sclerosis patients vary with disease activity, study finds

What is the role of SARS-CoV-2 non-structural protein 2 in repressing host antiviral immunity?

Does bimodal visual-olfactory training with patient-preferred scents improve olfaction in individuals with COVID-19 postviral olfactory loss?

What was the effect of the COVID-19 pandemic on the mental well-being of university students?

Are patients with a history of MIS-C at increased risk of adverse reactions from COVID-19 vaccination?

Wayne State researcher wins $1.7 million NIH award to understand and tackle cisplatin-induced ototoxicity

SynGAP Research Fund awards $180,000 grant to the University of Edinburgh Medical School's Patrick Wild Centre & Centre for Discovery Brain Sciences

Seroprevalence study demonstrates vaccination could boost impaired humoral immunity against Omicron BQ.1.1 subvariant

How does mindful attention change brain function to support self-regulation?

New research extensively explores 12 distinctive aging traits

Estimating the hospital costs associated with two of the most significant antibiotic-resistant organisms in Canada

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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