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Researchers gain new insights into ADHD drug's mechanism of action

For decades, doctors have treated kids with attention-deficit/hyperactivity disorder (ADHD) with methylphenidate, a stimulant drug sold as Ritalin and Concerta, making it one of the most widely prescribed medications aimed at the central nervous system.

8 Dec 2022

Study reveals how the HOXA5 gene may work to suppress breast cancer formation

Researchers at the Johns Hopkins Kimmel Cancer Center have revealed how the gene HOXA5 may work to suppress formation of breast cancers.

8 Dec 2022

New method uses light to change long-term behavior of neurons

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) and MIT have developed a new method to target diseased neurons in the brain and change their long-term behavior using light, paving the way for potential new treatments for neurological conditions such as epilepsy and autism.

8 Dec 2022

One-minute bursts of activity during daily tasks associated with reduction in risk of premature death

In good news for those who don't like playing sport or going to the gym, new research finds just three to four one-minute bursts of huffing and puffing during daily tasks is associated with large reductions in the risk of premature death, particularly from cardiovascular disease.

8 Dec 2022

Trial establishes the clinical utility of circulating tumor cell count as biomarker in breast cancer care

The use of circulating tumor cell (CTC) count to guide the choice between chemotherapy and endocrine therapy as first-line therapy for patients with metastatic, estrogen receptor (ER)-positive/HER2-negative breast cancer provided overall survival benefit, compared with physician's choice of treatment, according to data from the STIC CTC trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

8 Dec 2022

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma – a lethal form of salivary gland cancer that currently has no treatment options.

8 Dec 2022

COVID-19 vaccines may reduce long-COVID symptoms

A new study describes the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in reducing long-COVID symptoms.

8 Dec 2022

Exploring a variant-adapted SARS-CoV-2 recombinant protein vaccine

Researchers assessed the immunogenicity of a variant-adapted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recombinant protein vaccine boosted with an AS03 adjuvant.

8 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Adult females exhibit impaired muscle and pulmonary function after COVID-19 recovery

In a new study, researchers examined muscle and pulmonary dysfunction during moderate exercise in adult females who recovered from coronavirus disease 2019 (COVID-19).

8 Dec 2022

Exploring COVID-19 vaccination prioritization strategies for primary and booster doses

Researchers evaluated the coronavirus disease 2019 (COVID-19) vaccine, prioritizing options for primary and booster doses.

8 Dec 2022

Study explores the risk of new-onset diabetes mellitus following SARS-CoV-2 infections

Researchers evaluated individuals who had SARS-CoV-2 infections and were diagnosed with diabetes mellitus within six months of the onset of COVID-19 to understand the temporal relationship between SARS-CoV-2 infections and diabetes mellitus.

8 Dec 2022

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

Researchers investigated the immunological mechanisms behind the decreasing efficacy of COVID-19 vaccines by evaluating the durability and magnitude of neutralizing antibodies and memory B and T cell responses to booster doses of mRNA COVID-19 vaccine.

8 Dec 2022

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Fatty foods harm our health. Prior research has established a link between the consumption of dietary fats and non-alcoholic fatty liver disease, which subsequently leads to inflammation and tumor formation in the liver.

7 Dec 2022

Low-intensity ultrasound therapies may help rebuild stronger knees

Low-intensity ultrasound therapies may one day rebuild stronger knees following injury or surgery, thanks to research by Dr. Anu Subramanian at The University of Alabama in Huntsville (UAH) that's being supported by the National Institutes of Health.

7 Dec 2022

UKSRC researchers work with community partners to protect Kentuckians from 'forever chemicals'

Nearly every person in the United States has been exposed to per- and polyfluorinated alky substances (PFAS) at some point in their life.

7 Dec 2022

New 'heart attack on a chip' could serve as a testbed to develop personalized medicines

Researchers at the University of Southern California Alfred E. Mann Department of Biomedical Engineering have developed a "heart attack on a chip," a device that could one day serve as a testbed to develop new heart drugs and even personalized medicines.

7 Dec 2022

Medical Science News

Researchers gain new insights into ADHD drug's mechanism of action

Study reveals how the HOXA5 gene may work to suppress breast cancer formation

New method uses light to change long-term behavior of neurons

One-minute bursts of activity during daily tasks associated with reduction in risk of premature death

Trial establishes the clinical utility of circulating tumor cell count as biomarker in breast cancer care

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

COVID-19 vaccines may reduce long-COVID symptoms

Exploring a variant-adapted SARS-CoV-2 recombinant protein vaccine

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

Adult females exhibit impaired muscle and pulmonary function after COVID-19 recovery

Exploring COVID-19 vaccination prioritization strategies for primary and booster doses

Study explores the risk of new-onset diabetes mellitus following SARS-CoV-2 infections

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Low-intensity ultrasound therapies may help rebuild stronger knees

UKSRC researchers work with community partners to protect Kentuckians from 'forever chemicals'

New 'heart attack on a chip' could serve as a testbed to develop personalized medicines

Liver cancer study could help improve the safety of certain gene therapies for hemophilia

Scientists develop new receptor “decoy” drug that potently neutralizes SARS-CoV-2 variants

Vaccination against E. coli could help prevent some forms of childhood malnutrition, stunting

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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