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Scientists illuminate the molecular events underlying childhood movement disorder

Scientists at the UNC School of Medicine and UNC Eshelman School of Pharmacy, in collaboration with a team from Queen Mary University of London, have illuminated the molecular events underlying an inherited movement and neurodegenerative disorder known as ARSACS – Autosomal recessive spastic ataxia of Charlevoix-Saguenay, named for two Quebec valleys where the first cases were found.

3 Nov 2022

New closed-loop gene therapy approach to treat brain circuit disorders

On-demand expression of a gene that inhibits neuronal activity provides a way to reduce spontaneous seizures in mice, researchers report.

3 Nov 2022

Understanding the brain correlates of dissociative disorders

Trauma can cause dissociative symptoms - such as having an out-of-body experience, or feeling emotionally numb - that may help an individual cope in the short term but can have negative impacts if the symptoms persist for a long period of time.

3 Nov 2022

Study explores the potential use of anti-thymic stromal lymphopoietin monoclonal antibody as an adjuvant in allergic immunotherapy

A new study investigated the impact of a monoclonal anti-thymic stromal lymphopoietin (TSLP) antibody on subcutaneous allergen immunotherapy (SCIT) efficacy among patients with allergic rhinitis.

3 Nov 2022

Parental discord linked to children's genetic risk for alcohol problems

Parents can transmit a genetic risk for alcohol problems to their children not only directly, but also indirectly via genetically influenced aspects of the home environment, such as marital discord or divorce, according to a Rutgers researcher.

3 Nov 2022

SARS-CoV-2 infections may induce neuroinflammation

Researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on neuroinflammation.

3 Nov 2022

Blood clotting protein found to play a new role in repairing damaged blood vessels

Research by RCSI University of Medicine and Health Sciences has discovered a new role for the blood clotting protein, von Willebrand Factor (VWF), that could lead to the development of new treatments for patients with inflammatory and blood clotting disorders.

3 Nov 2022

The long-term impact of COVID-19 severity on health-related quality of life

A recent study conducted on the residents of Amsterdam, the Netherlands, describes that people with mild COVID-19 experience better health-related quality of life after one year of disease onset than those with moderate or severe COVID-19.

3 Nov 2022

A review of vaccines against the respiratory syncytial virus

This study reviewed the epidemiology, molecular characteristics, populations affected by the virus, and vaccines against RSV.

3 Nov 2022

What is the correlation between specific COVID-19 clinical characteristics and anti-SARS-CoV-2 antibody titers?

Researchers investigated the associations between clinical characteristics of coronavirus disease 2019 (COVID-19) and immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

3 Nov 2022

Investigating the role of the gut-to-brain axis in defensive responses

In a new study, researchers investigated the function of the gut-to-brain axis in defensive responses induced by toxins.

3 Nov 2022

Gut colonization by proteobacteria modulates mice’s neurobehavioral response to cocaine

A new study revealed that gut colonization by proteobacteria modulates cocaine neurobehavioral response in mice.

3 Nov 2022

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

In a recent study posted to the medRxiv* preprint server, researchers in the United States investigated the source of an enigmatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)-like spike (S) protein strain detected in wastewater but not in clinical samples.

2 Nov 2022

Vimentin is an important co-receptor for SARS-CoV-2 infection

Vimentin functions as a co-receptor for the entry of SARS-CoV-2 into host cells to facilitate infection.

2 Nov 2022

Scientists identify a broadly neutralizing antibody against all dominant SARS-CoV-2 variants

Researchers in the United States identified a broadly neutralizing antibody (S728-1157 bnAb) that targets the receptor-binding site (RBS) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Nov 2022

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell's Ithaca campus.

2 Nov 2022

A portable air sampler to quantify and capture SARS-CoV-2 aerosols in laboratories

Researchers in the United Kingdom evaluated a battery-operated portable air sampler that could recover severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aerosolized in a laboratory using a plaque assay.

2 Nov 2022

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Innate lymphoid cells are a recently discovered family of white blood cells that reside in the skin, gastrointestinal tract, airways and other barrier tissues of the body.

2 Nov 2022

Large-scale model of the primary visual cortex can accurately solve multiple visual processing tasks

HBP researchers have trained a large-scale model of the primary visual cortex of the mouse to solve visual tasks in a highly robust way.

2 Nov 2022

Ohio State researchers enter federal cooperative agreement to develop radiation biodosimetry solutions

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) have entered a federal cooperative agreement, valued up to $9.42 million, that will help them further develop Ohio State's biodosimetry technology to discover noninvasive biomarkers for radiation exposure – work that will have national security applications.

2 Nov 2022

Medical Science News

Scientists illuminate the molecular events underlying childhood movement disorder

New closed-loop gene therapy approach to treat brain circuit disorders

Understanding the brain correlates of dissociative disorders

Study explores the potential use of anti-thymic stromal lymphopoietin monoclonal antibody as an adjuvant in allergic immunotherapy

Parental discord linked to children's genetic risk for alcohol problems

SARS-CoV-2 infections may induce neuroinflammation

Blood clotting protein found to play a new role in repairing damaged blood vessels

The long-term impact of COVID-19 severity on health-related quality of life

A review of vaccines against the respiratory syncytial virus

What is the correlation between specific COVID-19 clinical characteristics and anti-SARS-CoV-2 antibody titers?

Investigating the role of the gut-to-brain axis in defensive responses

Gut colonization by proteobacteria modulates mice’s neurobehavioral response to cocaine

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

Vimentin is an important co-receptor for SARS-CoV-2 infection

Scientists identify a broadly neutralizing antibody against all dominant SARS-CoV-2 variants

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

A portable air sampler to quantify and capture SARS-CoV-2 aerosols in laboratories

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Large-scale model of the primary visual cortex can accurately solve multiple visual processing tasks

Ohio State researchers enter federal cooperative agreement to develop radiation biodosimetry solutions

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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