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Study suggests sleep disturbance is associated with dyspnoea, anxiety, and muscle weakness following COVID-19 hospitalization

Researchers used a multi-modal approach to examine the types, prevalence, and relevance of sleep disturbance in individuals hospitalized with COVID-19 and determine associations between dyspnea and sleep disturbance.

19 Dec 2022

Rise and waning of SARS-CoV-2 antibody responses induced by mRNA vaccine booster in a healthcare worker population

Researchers reported the waning of antibodies against SARS-CoV-2 in the six months following a booster dose of the mRNA COVID-19 vaccine.

19 Dec 2022

Safety and immunogenicity of the Omicron BA.4/BA.5-containing bivalent booster mRNA-1273.222

Researchers evaluated the immunogenicity and safety of the COVID-19 bivalent mRNA vaccine mRNA-1273.222 and tested the neutralizing ability of the two bivalent vaccines — mRNA-1273.222 and mRNA-1273.214 — against the newly emergent Omicron subvariants.

19 Dec 2022

Scientists make breakthrough in understanding how inflammation is regulated

Scientists from Trinity College Dublin have made an important breakthrough in understanding how inflammation is regulated. They have just discovered that a key immune alarm protein previously believed to calm down the immune response actually does the opposite.

16 Dec 2022

Origins of the serious cancer-like disease LCH discovered

The origins of the serious cancer-like disease LCH have been identified by researchers from Karolinska Institutet in collaboration with Karolinska University Hospital. The findings presented in Science Immunology may lead to new, targeted treatments.

16 Dec 2022

Study uncovers genetic cause of a novel developmental epilepsy syndrome

Neurodevelopmental disorders (NDD) encompass highly prevalent conditions such as autism and epilepsy, with cognitive disabilities alone affecting 1-3% of the global population.

16 Dec 2022

Research may pave the way for new antibiotics to treat high bacterial density infections

Antibiotic resistant bacteria pose of the greatest threats to global public health. In 2019, deaths due to antibiotic resistant bacteria outpaced deaths due to HIV and malaria.

16 Dec 2022

Exploring COVID-19 pandemic-related increases in hospitalizations among adolescents for mental health issues

Researchers conducted a retrospective, multisite cohort study among 11 to 17-year-old adolescents in the United States of America (USA) and France.

16 Dec 2022

Importance of pretend play for exploring the development of social cognition

Julia Wolf analyzes the importance of pretend play for exploring the development of social cognition.

16 Dec 2022

Excess COVID-19-associated death estimates by World Health Organization

Researchers presented a comprehensive report on the estimated impact of the SARS-CoV-2 pandemic by estimating month-wise excess deaths for the years 2020 and 2021.

16 Dec 2022

Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

Myocardial infarction is an ischemic disease in which a coronary artery supplying blood to the heart muscle is stenotic or obstructed, resulting in cardiac tissue necrosis.

16 Dec 2022

Current model for randomized clinical trials must be redesigned, world cardiology experts say

The current model for randomized clinical trials must be redesigned for the 21st century, according to the European Society of Cardiology (ESC), American Heart Association (AHA), World Heart Federation (WHF) and American College of Cardiology (ACC).

16 Dec 2022

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Researchers investigated whether coronavirus disease 2019 (COVID-19)-associated chemosensory alterations were predictive of serological responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among United States (US) residents.

16 Dec 2022

Study to determine if a DNA-based blood test can help detect cancer predisposition in NF1 patients

The Children’s Tumor Foundation (CTF) has announced a groundbreaking 3-year study, which it will fund for nearly $2 million, to determine if a DNA-based blood test can offer better understanding and ultimately earlier diagnosis of cancer predisposition in neurofibromatosis type 1 (NF1) patients.

16 Dec 2022

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers investigated the cellular tropism, replication competence, persistence and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, and associated histopathological changes in infected tissues.

16 Dec 2022

Novel immunotherapy offers a promising new strategy to fight hard-to-treat cancers

Scientists at UC San Francisco have engineered T cells to produce a potent anti-cancer cytokine, but only when they encounter tumor cells.

16 Dec 2022

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

New research at Cleveland Clinic expands the link between what we eat and how the gut microbiome impacts our susceptibility to develop different diseases – in this case, how a specific gut microbe-generated byproduct is linked to heart failure risk.

16 Dec 2022

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects.

16 Dec 2022

Adding Gli1+ cells could regenerate the enthesis after rotator cuff surgery

In the annals of shoulder surgery, NFL quarterback Drew Brees is an anomaly. In 2005, Brees was tackled and the rotator cuff tendon in his throwing shoulder was severely torn, a potentially career-ending injury.

16 Dec 2022

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

Researchers developed a one-dose subunit vaccine for the induction of durable, potent, and broad immunity against SARS-CoV-2.

16 Dec 2022

Medical Science News

Study suggests sleep disturbance is associated with dyspnoea, anxiety, and muscle weakness following COVID-19 hospitalization

Rise and waning of SARS-CoV-2 antibody responses induced by mRNA vaccine booster in a healthcare worker population

Safety and immunogenicity of the Omicron BA.4/BA.5-containing bivalent booster mRNA-1273.222

Scientists make breakthrough in understanding how inflammation is regulated

Origins of the serious cancer-like disease LCH discovered

Study uncovers genetic cause of a novel developmental epilepsy syndrome

Research may pave the way for new antibiotics to treat high bacterial density infections

Exploring COVID-19 pandemic-related increases in hospitalizations among adolescents for mental health issues

Importance of pretend play for exploring the development of social cognition

Excess COVID-19-associated death estimates by World Health Organization

Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

Current model for randomized clinical trials must be redesigned, world cardiology experts say

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Study to determine if a DNA-based blood test can help detect cancer predisposition in NF1 patients

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Novel immunotherapy offers a promising new strategy to fight hard-to-treat cancers

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Adding Gli1+ cells could regenerate the enthesis after rotator cuff surgery

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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