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Research reveals that a viral toxin may contribute to the severity of COVID-19

Researchers determine whether the SARS-CoV-2 spike protein influences endothelial and epithelial barrier dysfunction and vascular leakage.

14 Dec 2022

Severity of COVID-19 in men may be due to the loss of Y chromosome

Men are at an increased risk of a severe bout of COVID-19 compared to women. Researchers at Uppsala University have now shown that this may be due to loss of the Y chromosome in part of their white blood cells.

14 Dec 2022

Study finds a novel therapeutic target for prevention and treatment of gout

Many Americans think of gout as a disease from a bygone era, akin to rickets or scurvy. The condition commonly afflicted the rich and royal, including American historical figures such as Benjamin Franklin and Thomas Jefferson.

14 Dec 2022

Flexible assemblies of nerve cells appear to be key to successful episodic memory

For the first time, scientists have recorded human nerve cells firing together in flexible assemblies, a process that appears necessary to successfully encode long-term memories, a study led by UT Southwestern researchers reports.

14 Dec 2022

Updated guidelines seek to improve transparency and utility in clinical trial reporting

In a global study of outcome reporting in clinical trials, a research team at The Hospital for Sick Children (SickKids) has issued updated guidelines on what should be included in all trial protocols and published clinical trial reports, with the goal to improve their transparency and utility.

14 Dec 2022

Weak electrical pulses can stop certain life-threatening arrhythmias, study shows

Atrial and ventricular fibrillations are dangerous heart arrhythmias that claim millions of lives each year. Current treatment for them is a high-energy defibrillation shock that can be intensely painful and lead to further heart damage.

14 Dec 2022

Subcutaneous fat protects against brain inflammation in females

Females' propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopause, scientists report.

14 Dec 2022

Bioinformatics approach for the design of siRNAs against SARS-CoV-2

Scientists have developed a set of siRNAs against SARS-CoV-2 using computational approaches.

14 Dec 2022

The therapeutic effects and safety of psychedelics

Psychedelics are reported to have rapid-onset and long-lasting therapeutic benefits after a single or few doses.

14 Dec 2022

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Researchers elucidated the mechanisms of long-term T lymphocyte lodgement in tissues other than lymphoid tissues and the reasons for the transient residency of specific subsets of tissue-resident memory T (TRM) lymphocytes.

14 Dec 2022

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

Researchers evaluated the change in symptoms and risk factors associated with positive SARS-CoV-2 tests during the COVID-19 pandemic and compared it to those associated with positive tests of other respiratory viruses among residents of King County, Washington, in the United States.

14 Dec 2022

What is the relation between COVID-19 vaccination and new POTS-related diagnoses?

Researchers assessed the association between POTS and SARS-CoV-2 infections and COVID-19 vaccinations.

14 Dec 2022

The evolution of COVID-19 mortality during 2020 and 2021 in six countries

Researchers analyzed the mortality in selected countries during multiple waves of the COVID-19 pandemic in 2020 and 2021 to understand the evolution of COVID-19-related mortality according to age and sex.

14 Dec 2022

Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies

Researchers isolated SARS-CoV-2 spike protein-targeted mAbs from convalescent healthcare workers, emphasizing the IGHV1-69 gene, the gene with the greatest structural and allelic variation.

14 Dec 2022

Study indicates need for developing mucosal vaccines to induce potent immune responses at sites where SARS-CoV-2 infection occurs

Researchers measured the antibodies against SARS-CoV-2 from nasal fluid, saliva, and plasma to compare the antibody levels between blood and mucosal fluids.

14 Dec 2022

U-M leads multi-university partnership that aims to predict cognitive fatigue in individuals

Researchers at the University of Michigan are leading a multi-university partnership that aims to understand and predict cognitive fatigue in individuals.

13 Dec 2022

Study examines the role of brain-gut microbiome system in discrimination-related health issues

Structural racism has not only psychosocial but also biological consequences. Discrimination has been shown to contribute to mental and physical disorders including obesity, depression, and addiction, but the biological pathways from a social experience to its impacts on the body remain unknown.

13 Dec 2022

Study uncovers a new immune culprit in Alzheimer’s disease

The reason your three-pound brain doesn't feel heavy is because it floats in a reservoir of cerebrospinal fluid (CSF), which flows in and around your brain and spinal cord.

13 Dec 2022

Water enriched with hydrogen molecules improves symptomatology of neuropathic pain in animal models

In an article published in the journal Antioxidants, researchers from the Hospital de la Santa Creu i Sant Pau Research Institute (IIB Sant Pau) and the Universitat Autònoma de Barcelona demonstrate in animal models that water enriched with hydrogen molecules (H2) improves the symptomatology of neuropathic pain and related emotional disturbances.

13 Dec 2022

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

In a recent study posted to bioRxiv*, researchers in the United States assessed the impact of metabolic diseases on coronavirus disease 2019 (COVID-19) vaccine immunogenicity in a mouse model.

13 Dec 2022

Medical Science News

Research reveals that a viral toxin may contribute to the severity of COVID-19

Severity of COVID-19 in men may be due to the loss of Y chromosome

Study finds a novel therapeutic target for prevention and treatment of gout

Flexible assemblies of nerve cells appear to be key to successful episodic memory

Updated guidelines seek to improve transparency and utility in clinical trial reporting

Weak electrical pulses can stop certain life-threatening arrhythmias, study shows

Subcutaneous fat protects against brain inflammation in females

Bioinformatics approach for the design of siRNAs against SARS-CoV-2

The therapeutic effects and safety of psychedelics

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

What is the relation between COVID-19 vaccination and new POTS-related diagnoses?

The evolution of COVID-19 mortality during 2020 and 2021 in six countries

Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies

Study indicates need for developing mucosal vaccines to induce potent immune responses at sites where SARS-CoV-2 infection occurs

U-M leads multi-university partnership that aims to predict cognitive fatigue in individuals

Study examines the role of brain-gut microbiome system in discrimination-related health issues

Study uncovers a new immune culprit in Alzheimer’s disease

Water enriched with hydrogen molecules improves symptomatology of neuropathic pain in animal models

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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