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New microbiome-based predictive models to forecast human health outcomes

A new approach that uses artificial intelligence (AI) shows how to use microorganisms in the body and molecules in cells to predict human health outcomes, according to Penn State College of Medicine and University of Texas Southwestern Medical Center researchers.

19 Jul 2022

Molnupiravir does not induce resistance mutations in SARS-CoV-2 genome

A new study has pointed out that Molnupiravir treatment increases the ratio of transition to transversion mutations in COVID-19 patients and that the treatment does not appear to induce resistance mutations in the SARS-CoV-2 genome.

19 Jul 2022

Study shows how a critical Lassa virus protein drives infection

Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15 percent in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine or antiviral to protect against Lassa virus.

19 Jul 2022

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Researchers at University of California San Diego School of Medicine previously found a set of human gene mutations that protect older adults against cognitive decline and dementia.

19 Jul 2022

What is the optimal alcohol consumption level to minimize health loss?

Researchers performed a population-scale analysis of alcohol consumption by amount, age, gender, region, and year to estimate the theoretical minimum risk exposure level (TMREL) and the non-drinker equivalence (NDE).

19 Jul 2022

Pain control method has revolutionized the experience for bone marrow donors, reduced the need for opioids

Sharing gifts is a favorite way to sustain connection across peoples and cultures worldwide, but with bone marrow donation the gift-giving act is accompanied by uncomfortable side effects to the donor, making it a truly selfless expression of kindness.

19 Jul 2022

What is the impact of SARS-CoV-2 variant booster vaccinations?

Researchers conducted preliminary assessments of a booster vaccination with the SARS-CoV-2 variant vaccines.

19 Jul 2022

Researchers report genomic profiling from more than 110,000 tumors

Researchers analyzed data from the latest public release of the GENIE project of the American Association for Cancer Research.

19 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Influence of chr12q24.13 domain on COVID-19 severity

Researchers evaluated the probable impact of the chr12q24.13 domain on the outcomes of laboratory-validated SARS-CoV-2 infection.

19 Jul 2022

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Researchers studied open and closed conformations of the C-terminal of SARS-CoV-2 nucleocapsid (N) protein termed the NCTD.

19 Jul 2022

What were the drivers of influenza decline during the COVID-19 pandemic?

Researchers investigated the potential drivers of a global decline in influenza virus circulation during the COVID-19 pandemic.

19 Jul 2022

Could Vitamin B6 Reduce Anxiety and Depression?

In this interview, we speak to Dr. David Field about his latest research into anxiety and depression and whether vitamin B6 supplements could help to reduce it.

19 Jul 2022

What is the efficacy of the second, third, and fourth dose of the COVID-19 mRNA vaccine?

Investigators examined the effectiveness of two, three, and four SARS-CoV-2 vaccine doses during the Omicron prevalent phases.

19 Jul 2022

Should siRNA-based antivirals be added to the COVID toolbox?

A recent study reviewed the existing treatment modalities, including vaccines and antivirals, for SARS-CoV-2 infection.

19 Jul 2022

Sex matters when it comes to immune responses to vaccines and viral infections

A review published in Frontiers in Aging analyzed the sex differences in the safety, effectiveness, and immunogenicity of influenza and COVID-19 vaccines in older individuals. It also analyzed the way sex brings about the modification of the impact of age-related factors on vaccination.

18 Jul 2022