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CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

AbbVie today announced the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended the approval of upadacitinib (RINVOQ® 15 mg, once daily) for the treatment of active non-radiographic axial spondyloarthritis (nr‑axSpA) in adult patients with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI), who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs).*

27 Jun 2022

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

27 Jun 2022

Biodegradable nanomaterials can take images and deliver medicine to combat peripheral arterial disease

A University of Texas at Arlington bioengineer is leading a project that will develop biodegradable nanomaterials that will take pictures and deliver medicine to combat peripheral arterial disease (PAD).

24 Jun 2022

Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Most research on immunity to the SARS-CoV-2 virus and COVID-19 vaccine development has focused on antibody responses to the spike protein and other viral surface proteins.

24 Jun 2022

Study uncovers cryptic vulnerabilities in RET oncogene that could aid in anti-cancer drug design

RET is a receptor protein with tyrosine kinase activity that can transfer a phosphate group from ATP to other molecules modifying their shape and function in signaling pathways that are essential to organogenesis and tissue maintenance.

24 Jun 2022

New mathematical model can simulate motor learning in humans

Even seemingly simple movements are very complex to perform, and the way we learn how to perform new movements remains unclear.

24 Jun 2022

Scientists develop suitable human cell line for anti-SARS-CoV-2 drug screening

Scientists have described the development of a modified A549 cell line that shows a robust expression of ACE2 and TMPRSS2 and high susceptibility to SARS-CoV-2 infection.

24 Jun 2022

Serologic testing captures missed children at risk for long Covid

A new study provides evidence of the utility of serologic testing in helping to pick up children with long Covid following missed diagnoses of COVID-19.

24 Jun 2022

Vagus nerve stimulation for long COVID

Researchers assessed the effectiveness of transcutaneous auricular vagus nerve stimulation (taVNS) in managing long COVID-19.

24 Jun 2022

Natural and hybrid immunity dynamics in South African mothers

Researchers evaluated natural and hybrid immunity after four COVID-19 waves in South Africa.

24 Jun 2022

Associations between maternal COVID-19 vaccination and hospitalization among infants

Researchers assessed the efficacy of maternal mRNA vaccinations during pregnancy against hospitalization for COVID-19 in infants aged <6 months.

24 Jun 2022

#Plandemic and #Scamdemic tweets during the COVID-19 pandemic

Researchers analyzed COVID-19 disinformation on Twitter.

24 Jun 2022

Symptomatology of long COVID among children below 14 years of age in Denmark

Researchers investigated long COVID symptoms among SARS-CoV-2-infected Danish children below 14 years of age.

24 Jun 2022

Characterization of SARS-CoV-2 Omicron persistence and infectivity among children

Researchers characterized the persistence and infectivity of SARS-CoV-2 Omicron among children.

24 Jun 2022

Mapping the trajectory of SARS-CoV-2 evolution inside the host

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States mapped the trajectory of within-host evolution of acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

24 Jun 2022

New molecular information could help develop more effective treatments for melanoma

A new study reveals important molecular information that could help scientists develop more effective treatment and prevention strategies for a difficult-to-treat form of melanoma skin cancer.

24 Jun 2022

Scientists discover mechanism behind zoonotic transfer of SARS-CoV-2 virus

The original SARS-CoV-2 viral strain that emerged in early 2020 was able to latch on to sugars known as sialic acids, found on the surface of human cells, an ability that later strains did not retain.

24 Jun 2022

Three-dimensional microscope data reveals an expanded network of interneurons in the human brain

The analysis of the human brain is a central goal of neuroscience. However, for methodological reasons, research has largely focused on model organisms, in particular the mouse.

23 Jun 2022

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

Study finds a more effective treatment option for HER2 mutant metastatic breast cancer

Breast cancers with HER2 mutations respond to the drug neratinib, but the responses are variable and often not durable.

23 Jun 2022

Medical Science News

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

Biodegradable nanomaterials can take images and deliver medicine to combat peripheral arterial disease

Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Study uncovers cryptic vulnerabilities in RET oncogene that could aid in anti-cancer drug design

New mathematical model can simulate motor learning in humans

Scientists develop suitable human cell line for anti-SARS-CoV-2 drug screening

Serologic testing captures missed children at risk for long Covid

Vagus nerve stimulation for long COVID

Natural and hybrid immunity dynamics in South African mothers

Associations between maternal COVID-19 vaccination and hospitalization among infants

#Plandemic and #Scamdemic tweets during the COVID-19 pandemic

Symptomatology of long COVID among children below 14 years of age in Denmark

Characterization of SARS-CoV-2 Omicron persistence and infectivity among children

Mapping the trajectory of SARS-CoV-2 evolution inside the host

New molecular information could help develop more effective treatments for melanoma

Scientists discover mechanism behind zoonotic transfer of SARS-CoV-2 virus

Three-dimensional microscope data reveals an expanded network of interneurons in the human brain

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

Study finds a more effective treatment option for HER2 mutant metastatic breast cancer

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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