Molecular & Structural Biology

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'Jumping' DNA influences the differentiation, physiological functioning of neurons

The human genome contains over 4.5 million sequences of DNA called "transposable elements", these virus-like entities that "jump" around and help regulate gene expression.

28 Aug 2020

Exploring the structure and dynamics of biological nanomachine

A small but important step towards a successful immune reaction is performed by an impressive nanomachine. Researchers use simulations to understand how it works.

28 Aug 2020

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Alberto Yáñez Boyer, Ramón y Cajal researcher at BIOTECMED (Interdisciplinary Research Structure in Biotechnology and Biomedicine) and the Department of Microbiology and Ecology at the University of Valencia (UV), participates in a study on the C9orf72 gene and its mutations in the immune system.

28 Aug 2020

Manipulating 3D Printed Organoid Microenvironments

Organoids are 3-dimensional (3D) clusters of stem cells that come together and emulate the microenvironment within individual organs, whether that be liver, kidney, heart, gut or other specific organs.

From Manchester BIOGEL 28 Aug 2020

DNA structure is determined by spatial rules based on specific protein sequences and their order

DNA three-dimensional structure is determined by a series of spatial rules based on particular protein sequences and their order.

28 Aug 2020

Researchers observe how two proteins operate at tricellular junctions

Organs in animals and in humans have one thing in common: they are bounded by so-called epithelial cells.

27 Aug 2020

Researchers identify RNA molecule that aids in lung cancer immune evasion

Researchers in Spain have identified a non-coding RNA molecule that helps lung cancer cells proliferate and avoid being killed by the body's immune cells.

27 Aug 2020

Largely ignored 'housekeeping' gene plays a role in seizures

Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.

26 Aug 2020

Universities collaborate to develop COVID-19 virus-trapping materials

Researchers around the world are racing to find treatments to tackle the COVID-19 pandemic that has caused more than 16 million human infections globally.

25 Aug 2020

New approach provides a roadmap for linking neurological and locomotor deficits

Locomotion deficits, such as lack of coordination, a shuffling gait, or loss of balance, can result from neurological conditions, specifically those that affect motor areas of the nervous system.

24 Aug 2020

RNA-targeting compound restarts a healing factor silenced by heart attack

A heart attack can leave parts of the heart permanently scarred and stiff, resulting in prolonged disability and potential progression toward heart failure. Scientists have studied various ways to repair or regenerate such damaged heart tissue, with limited success.

24 Aug 2020

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Researchers at Osaka University identify vicious cycle involving RNA exosome that accelerates disease progression in FTLD/ALS

24 Aug 2020

New bioluminescent reporter developed to track DNA double stranded break repair

A new bioluminescent reporter that tracks DNA double stranded break repair in cells has been developed by researchers from Massachusetts General Hospital and the Academia Sinica in Taiwan.

21 Aug 2020

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

Research from Chapman University provides new insight into the characteristics of crucial proteins within the ciliary membrane that play vital roles in human genetic diseases and cardiovascular functions.

20 Aug 2020

UT leads new project to explore the mysteries of brain connections

Researchers at The University of Texas at Austin will lead an ambitious new project with 10 other U.S. institutions and global partners that has significant implications for understanding human brain health.

19 Aug 2020

Study sheds light on 500-year old mystery about the human heart

Researchers have investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart. The study, published in the journal Nature, sheds light on questions asked by Leonardo da Vinci 500 years ago, and shows how the shape of these muscles impacts heart performance and heart failure.

19 Aug 2020

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

ETH Zurich scientists have developed an RNA molecule that can be used in bone marrow cells to correct genetic errors that affect protein production.

18 Aug 2020

Researchers solve a long-held mystery of X chromosome inactivation

Researchers at Massachusetts General Hospital (MGH) have solved a mystery that has long puzzled scientists: How do the bodies of female humans and all other mammals decide which of the two X chromosomes it carries in each cell should be active and which one should be silent?

18 Aug 2020

Switching off 'master regulator' may protect critical brain cells from Parkinson's-related damage

Switching off a molecular "master regulator" may protect the brain from inflammatory damage and neurodegeneration in Parkinson's disease, reports a study published today in Nature Neuroscience.

17 Aug 2020

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

17 Aug 2020

Molecular & Structural Biology

'Jumping' DNA influences the differentiation, physiological functioning of neurons

Exploring the structure and dynamics of biological nanomachine

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Manipulating 3D Printed Organoid Microenvironments

DNA structure is determined by spatial rules based on specific protein sequences and their order

Researchers observe how two proteins operate at tricellular junctions

Researchers identify RNA molecule that aids in lung cancer immune evasion

Largely ignored 'housekeeping' gene plays a role in seizures

Universities collaborate to develop COVID-19 virus-trapping materials

New approach provides a roadmap for linking neurological and locomotor deficits

RNA-targeting compound restarts a healing factor silenced by heart attack

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

New bioluminescent reporter developed to track DNA double stranded break repair

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

UT leads new project to explore the mysteries of brain connections

Study sheds light on 500-year old mystery about the human heart

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

Researchers solve a long-held mystery of X chromosome inactivation

Switching off 'master regulator' may protect critical brain cells from Parkinson's-related damage

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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