Molecular & Structural Biology

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Modified CRISPR/Cas9 complex targets specific histones

Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle.

9 Feb 2021

New molecular tool can be used to study single synapses of neurons

Neurons are the primary cells of the nervous system, and the signals that are transmitted between them are responsible for all our actions and our cognitive ability.

9 Feb 2021

Study explores how membraneless organelles form and organize themselves

In cells, numerous important biochemical functions take place within spherical chambers made from proteins and RNA.

9 Feb 2021

Study provides key insight into the neural mechanism of attention selection in primates

This discovery was made possible by applying the research method for the comparison of the brain activity between monkeys and humans to artificial neural networks.

9 Feb 2021

Study shows how the brain quickly adjusts to group opinions

Scientists at HSE University have learned that disagreeing with the opinion of other people leaves a 'trace' in brain activity, which allows the brain to later adjust its opinion in favor of the majority-held point of view.

8 Feb 2021

Researchers find new clues to how SARS-CoV-2 infects cells

The molecular details of how SARS-CoV-2 enters cells and infects them are still not clear. Researchers at Uppsala University have tested the bioinformatic predictions made by another research group and have identified receptors that could be important players in the process.

8 Feb 2021

Researchers identify a new drug target for Ebola, Marburg viruses

Ebola and Marburg are among the most deadly viruses, with mortality rates from these infections ranging from 25% to 90%.

8 Feb 2021

Study implicates disruption in prenatal neurogenesis in the development of ASDs

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

8 Feb 2021

Study finds structural similarities between SARS-CoV-2 and pangolin coronavirus

Scientists at the Francis Crick Institute have found important structural similarities between SARS-CoV-2 and a pangolin coronavirus, suggesting that a pangolin coronavirus could infect humans.

7 Feb 2021

Researchers elucidate mechanism by which blood and lymph vessels remain separated

Researchers from Kumamoto University (Japan) have clarified the mechanism by which blood and lymph vessels remain segregated from one another after development.

6 Feb 2021

Gene panel test enables highly accurate diagnosis of liposarcomas

Researchers have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel test that allows for highly accurate diagnosis of the most common types of liposarcoma.

5 Feb 2021

Imaging SARS-CoV-2 with a helium ion microscope for the first time

Scientists at Bielefeld University's Faculty of Physics have succeeded for the first time in imaging the SARS-CoV-2 coronavirus with a helium ion microscope.

4 Feb 2021

Researchers shed new light on how the brain ages

Parts of the brain decline faster from age 30, researchers at the University of Oslo find. These brain changes are accelerated in people with Alzheimer's disease.

4 Feb 2021

Applications and Advantages of High-Speed AFM

AZoM talks to Professor Toshio Ando about his interest in high-speed AFM (HS-AFM) and how it can revolutionize observation of protein molecules.

From Bruker Nano Surfaces and Metrology 4 Feb 2021

Scientists unravel the workings of a mysterious protein implicated in movement disorders

Scientists at Scripps Research have clarified the workings of a mysterious protein called Gαo, which is one of the most abundant proteins in the brain and, when mutated, causes severe movement disorders.

3 Feb 2021

Study gives new clues to how muscle wasting occurs on a cellular level

Muscle wasting, or the loss of muscle tissue, is a common problem for people with cancer, but the precise mechanisms have long eluded doctors and scientists. Now, a new study led by Penn State researchers gives new clues to how muscle wasting happens on a cellular level.

3 Feb 2021

New process separates beneficial glucocorticoids from unwanted side-effects

A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an optimization process they named "ligand class analysis."

3 Feb 2021

Evolutionary history reveals the function of fish and human bitter receptors

To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients.

2 Feb 2021

Researchers develop rapid COVID-19 diagnostic test affordable for low-income families

A test that detects antibodies to the novel coronavirus in 10 minutes and costs only a fifth of the market average has been developed by researchers at the University of São Paulo's São Carlos Chemistry Institute and Brazilian startup Biolinker, with São Paulo Research Foundation - FAPESP's support.

2 Feb 2021