Molecular & Structural Biology

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Study: Neurons expressing dopamine D2 receptors have different molecular features, functions

Study: Neurons expressing dopamine D2 receptors have different molecular features, functions

An international collaboration, which included the involvement of the research team from the Institut de Neurociències of the UAB (INC-UAB), has shown that neurons expressing dopamine D2 receptors have different molecular features and functions, depending on their anatomical localization within the striatum.

14 May 2020

Study uncovers how the body synthesizes triglycerides

Study uncovers how the body synthesizes triglycerides

Doctors regularly warn their patients that having high levels of triglycerides, a major dietary fat, can increase the risk of heart disease, diabetes, obesity and fatty liver disease.

13 May 2020

A deep look into hormone-producing cells of the gut

A deep look into hormone-producing cells of the gut

Researchers from the Hubrecht Institute and Utrecht University generated an in-depth description of the human hormone-producing cells of the gut, in a large collaborative effort with other research teams. The results are presented in the scientific journal Cell on the 13th of May.

13 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

First detailed study of the epigenetic landscape of human tumor organoids

Frequently, promising cancer therapies fail when applied to patients in the real clinical setting. This occurs despite many of these new treatments demonstrating promising results at the preclinical stage in the lab.

13 May 2020

Researchers make a significant leap in mucus biology

Researchers make a significant leap in mucus biology

Worldwide, hundreds of millions of people are impacted by chronic respiratory disease. COPD alone affects more than 250 million people, causing 3 million deaths each year.

13 May 2020

Scientists uncover important functions of a special protein during cell division

Scientists uncover important functions of a special protein during cell division

In a new study, researchers from the University of Copenhagen have discovered two important functions of a protein called RTEL1 during cell division.

12 May 2020

RNA interference machinery influences epithelial cell biology

RNA interference machinery influences epithelial cell biology

Epithelial cells are held together and connected by several different types of structures that form cell-cell contacts.

9 May 2020

More selective elimination of leukemic and hematopoietic stem cells

More selective elimination of leukemic and hematopoietic stem cells

Acute myeloid leukemia is an aggressive cancer of the blood-forming system. It affects the hematopoietic stem cells, or blood stem cells, of various white blood cells and of the red blood cells and platelets.

8 May 2020

Foxg1 gene works like a molecular knob to control neocortical activity

Foxg1 gene works like a molecular knob to control neocortical activity

It works like a very fine "molecular knob" able to modulate the electrical activity of the neurons of our cerebral cortex, crucial to the functioning of our brain.

8 May 2020

Scientists discover new metabolism regulation system for the brown adipose tissue

Scientists discover new metabolism regulation system for the brown adipose tissue

Scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes.

8 May 2020

The Role of Microphysiological Systems for Oncology and Stem Cell Research

The Role of Microphysiological Systems for Oncology and Stem Cell Research

In this interview, Dr. Nancy Allbritton from The Allbritton Lab talks to News-Medical and Life Sciences about the revolutionary technology and techniques for the application of new technologies for oncology and stem cell research.

From Pittcon 6 May 2020

Discovery heralds a new strategy in the hunt for antibiotics

Discovery heralds a new strategy in the hunt for antibiotics

Scientists have identified a key process in the way bacteria protect themselves from attack - and it heralds a new strategy in the hunt for antibiotics.

3 May 2020

Real-time monitoring of biochemical processes on DNA using infrared spectroscopy

Real-time monitoring of biochemical processes on DNA using infrared spectroscopy

DNA damage in general and DNA strand breaks in particular occur every day in all cells of the human body.

3 May 2020

Study reports cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2

Study reports cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2

A team of Chinese scientists have reported the high-resolution cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2, the infective virus of COVID-19.

3 May 2020

DNA damage and inaccurate repair mechanisms jointly cause mutational signatures

DNA damage and inaccurate repair mechanisms jointly cause mutational signatures

Researchers at EMBL's European Bioinformatics Institute, the University of Dundee and the Wellcome Sanger Institute analysed over 2700 genomes from C. elegans worms in order to better understand the causes of mutations.

2 May 2020

Using Multiplex Assays to Discover Biomarkers for Parkinson’s Disease

Using Multiplex Assays to Discover Biomarkers for Parkinson’s Disease

In this interview, Dr. Polinski and Dr. Atabakhsh discuss the importance of developing biomarkers for Parkinson’s and the partnership between MJFF and Abcam.

From Abcam 1 May 2020

WSU researchers crack the Lyme disease code

WSU researchers crack the Lyme disease code

The next time a tick feeds on you, Washington State University researchers hope to make sure persistent arthritis caused by Lyme disease doesn't linger for a lifetime.

30 Apr 2020

KU Leuven study uncovers how signaling molecule plays key role in learning process

KU Leuven study uncovers how signaling molecule plays key role in learning process

Neurobiologists at KU Leuven have discovered how the signalling molecule Neuromedin U plays a crucial role in our learning process.

29 Apr 2020

Studies show how sex-determining genes affect courtship and aggression behaviors

Studies show how sex-determining genes affect courtship and aggression behaviors

Fruit flies, like many animals, engage in a variety of courtship and fighting behaviors. Now, Salk scientists have uncovered the molecular mechanisms by which two sex-determining genes affect fruit fly behavior.

28 Apr 2020

Researchers recreate how toxins from smoking cause DNA damage

Researchers recreate how toxins from smoking cause DNA damage

Researchers from the University of York have recreated how toxins from smoking cause unique patterns of DNA damage.

28 Apr 2020

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