Molecular & Structural Biology

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Study addresses evolutionary rates of larval and adult life stages at a large scale

If you have any children in your life, imagine for a moment that they don't look anything like their parents, they don't eat anything humans normally eat, and they're active only while adults sleep.

5 Sep 2020

New model offers insight into how the brain becomes aware of information

When we watch a movie or hear an orchestra playing, it seems that we perceive images and sounds as a continuous stream of information.

3 Sep 2020

Research provides a map of coronavirus entry factors across the human body

An infection with the coronavirus SARS-CoV-2 can affect multiple organs. With this in mind, researchers of the German Center for Neurodegenerative Diseases and Cornell University in the US have investigated cellular factors that could be significant for an infection.

3 Sep 2020

Researchers identify a pattern in cancer’s chromosomal chaos

Researchers at the Francis Crick Institute and the UCL Cancer Institute have identified how different cancers go through some of the same genetic mutations at the same point in their evolution.

3 Sep 2020

Scientists aim to find cortisone alternatives with fewer side effects

Many people use cortisone of a regular basis. It is used for treating rheumatism, asthma, multiple sclerosis, or even COVID-19.

2 Sep 2020

Researchers create new and quicker method of diagnosing diseases

A new and quicker method of diagnosing diseases in patients has been created by researchers at the University of Leeds.

2 Sep 2020

New EU research project seeks to kickstart the development of "Organoid Cell Atlas"

HCA|Organoid is a new EU research project that combines single-cell profiling and organoid technology to validate organoids as faithful models of human biology.

31 Aug 2020

'Jumping' DNA influences the differentiation, physiological functioning of neurons

The human genome contains over 4.5 million sequences of DNA called "transposable elements", these virus-like entities that "jump" around and help regulate gene expression.

28 Aug 2020

Exploring the structure and dynamics of biological nanomachine

A small but important step towards a successful immune reaction is performed by an impressive nanomachine. Researchers use simulations to understand how it works.

28 Aug 2020

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Alberto Yáñez Boyer, Ramón y Cajal researcher at BIOTECMED (Interdisciplinary Research Structure in Biotechnology and Biomedicine) and the Department of Microbiology and Ecology at the University of Valencia (UV), participates in a study on the C9orf72 gene and its mutations in the immune system.

28 Aug 2020

Manipulating 3D Printed Organoid Microenvironments

Organoids are 3-dimensional (3D) clusters of stem cells that come together and emulate the microenvironment within individual organs, whether that be liver, kidney, heart, gut or other specific organs.

From Manchester BIOGEL 28 Aug 2020

DNA structure is determined by spatial rules based on specific protein sequences and their order

DNA three-dimensional structure is determined by a series of spatial rules based on particular protein sequences and their order.

28 Aug 2020

Researchers observe how two proteins operate at tricellular junctions

Organs in animals and in humans have one thing in common: they are bounded by so-called epithelial cells.

27 Aug 2020

Researchers identify RNA molecule that aids in lung cancer immune evasion

Researchers in Spain have identified a non-coding RNA molecule that helps lung cancer cells proliferate and avoid being killed by the body's immune cells.

27 Aug 2020

Largely ignored 'housekeeping' gene plays a role in seizures

Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.

26 Aug 2020

Universities collaborate to develop COVID-19 virus-trapping materials

Researchers around the world are racing to find treatments to tackle the COVID-19 pandemic that has caused more than 16 million human infections globally.

25 Aug 2020

New approach provides a roadmap for linking neurological and locomotor deficits

Locomotion deficits, such as lack of coordination, a shuffling gait, or loss of balance, can result from neurological conditions, specifically those that affect motor areas of the nervous system.

24 Aug 2020

RNA-targeting compound restarts a healing factor silenced by heart attack

A heart attack can leave parts of the heart permanently scarred and stiff, resulting in prolonged disability and potential progression toward heart failure. Scientists have studied various ways to repair or regenerate such damaged heart tissue, with limited success.

24 Aug 2020

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Researchers at Osaka University identify vicious cycle involving RNA exosome that accelerates disease progression in FTLD/ALS

24 Aug 2020

New bioluminescent reporter developed to track DNA double stranded break repair

A new bioluminescent reporter that tracks DNA double stranded break repair in cells has been developed by researchers from Massachusetts General Hospital and the Academia Sinica in Taiwan.

21 Aug 2020