Molecular & Structural Biology

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Scientists discover how resistant bacteria block entrance of antibiotics

Scientists have discovered how Klebsiella pneumoniae evolves to become resistant to carbapenem antibiotics.

2 Sep 2019

Lab-grown brain organoids and the brains of preemie babies generate similar electrical impulses

Brain organoids — also called mini-brains — are 3D cellular models that represent aspects of the human brain in the laboratory. Brain organoids help researchers track human development, unravel the molecular events that lead to disease and test new treatments.

30 Aug 2019

Researchers identify how neurons in the mouse neocortex form billion synaptic connections

The structure of synaptic connections between neurons shapes their activity and function. Measuring a comprehensive snapshot of this so-called connectome has so far only been accomplished within tiny volumes, smaller than the head of a pin.

30 Aug 2019

Molecular mechanism by which human stomach pathogen is attracted to bleach revealed

Researchers at the University of Oregon have uncovered a molecular mechanism by which the human stomach pathogen Helicobacter pylori is attracted to bleach, also known as hypochlorous acid or HOCI.

30 Aug 2019

Cell-free DNA identifies pathogens and quantifies injuries to organs

A common problem in diagnosing infectious disease is that the presence of a potential pathogen in the body does not necessarily mean the patient is sick. This can be particularly challenging for the treatment of organ transplant recipients, who often grapple with infection as well as complications related to immunosuppression.

29 Aug 2019

The Kavli Foundation gifts $3 million to support neuroscience research at Salk

The Salk Institute announced today that The Kavli Foundation has committed $3 million to support ongoing neuroscience research at Salk as part of the joint UCSD-Salk Kavli Institute for Brain and Mind.

29 Aug 2019

New NC State-led project to focus on the future of biomanufacturing

A new 5-year project led by North Carolina State University will sponsor an international collaborative research and training program in biomanufacturing science and technology.

29 Aug 2019

'Clock in a dish' provides new way to replicate developmental disorders

In early mammalian development, timing is everything. For healthy development to occur -- whether it be three weeks for a mouse or nine months for a human -- embryos follow the lead of oscillating genes, which turn on and off in precise cycles and trigger different development milestones. Oscillating genes are conductors keeping time in a symphony of growth.

29 Aug 2019

Scientists reveal the structure of a key protein in Epstein-Barr virus infection

Scientists at the Institute for Research in Biomedicine and the Molecular Biology Institute of Barcelona have published a study in the journal Nature Communications revealing the structure of a key protein, known as a portal, in Epstein-Barr virus infection.

29 Aug 2019

[BC]2 conference focuses on use of big data in molecular medicine

From 9 to 11 September, the [BC]2 Basel Computational Biology Conference, organized by the SIB Swiss Institute of Bioinformatics, will bring together international and Swiss-based scientists working in this field, in one of the key bioinformatics events in Europe: a prime opportunity to hear from leading experts, from precision oncology to infectious diseases.

29 Aug 2019

Hyperactive signaling pathway blocks cell division in the aging brain

Scientists from Basel have investigated the activity of stem cells in the brain of mice and discovered a key mechanism that controls cell proliferation.

29 Aug 2019

Study proves that auditory pathways are more specialized in speech than previously assumed

Neuroscientists at TU Dresden were able to prove that speech recognition in humans begins in the sensory pathways from the ear to the cerebral cortex and not, as previously assumed, exclusively in the cerebral cortex itself.

28 Aug 2019

New cellular processes controlling the formation of lymphatic valves found

Lymphedema, resulting from a damaged lymphatic system, can be a debilitating disease in which excess protein-rich fluid (lymph) collects in soft tissues and causes swelling -- most often in the arms or legs.

28 Aug 2019

$1.5 million grant from BRAIN Initiative will help develop new tools to study astrocytes

In the brain, cells called astrocytes are at least as abundant as neurons, but are much less understood.

27 Aug 2019

Scientists reveal cancer cells' immune weak spot

Scientists have found a vulnerability in cancer cells that could make them more susceptible to being destroyed by the immune system, according to a new report in eLife.

27 Aug 2019

U of T scientists create antibodies with enormous potential for regenerative medicine

Our body makes antibodies to fight infections. But the synthetic versions of these molecules could hold the key to stimulating the body's ability to regenerate.

27 Aug 2019

Researchers reveal skin cream’s true molecular structure

Anyone who has gone through the stress and discomfort of raw, irritated skin knows the relief that comes with slathering on a creamy lotion.

27 Aug 2019

New method maps surface protein complements on large numbers of individual exosomes

There is a growing demand for diagnostic markers for early disease detection and prognosis. Exosomes are potential biomarkers for cancer progression and neurodegenerative disease but it can be difficult to identify what tissue a specific exosome comes from.

27 Aug 2019

Failure of glial cells in the brain triggers epileptic seizures, study finds

Epileptic seizures can happen to anyone. But how do they occur and what initiates such a rapid response?

27 Aug 2019

New study provides unprecedented insights into retina's genetic code

Australian scientists have led the development of the world's most detailed gene map of the human retina, providing new insights which will help future research to prevent and treat blindness.

27 Aug 2019

Molecular & Structural Biology

Scientists discover how resistant bacteria block entrance of antibiotics

Lab-grown brain organoids and the brains of preemie babies generate similar electrical impulses

Researchers identify how neurons in the mouse neocortex form billion synaptic connections

Molecular mechanism by which human stomach pathogen is attracted to bleach revealed

Cell-free DNA identifies pathogens and quantifies injuries to organs

The Kavli Foundation gifts $3 million to support neuroscience research at Salk

New NC State-led project to focus on the future of biomanufacturing

'Clock in a dish' provides new way to replicate developmental disorders

Scientists reveal the structure of a key protein in Epstein-Barr virus infection

[BC]2 conference focuses on use of big data in molecular medicine

Hyperactive signaling pathway blocks cell division in the aging brain

Study proves that auditory pathways are more specialized in speech than previously assumed

New cellular processes controlling the formation of lymphatic valves found

$1.5 million grant from BRAIN Initiative will help develop new tools to study astrocytes

Scientists reveal cancer cells' immune weak spot

U of T scientists create antibodies with enormous potential for regenerative medicine

Researchers reveal skin cream’s true molecular structure

New method maps surface protein complements on large numbers of individual exosomes

Failure of glial cells in the brain triggers epileptic seizures, study finds

New study provides unprecedented insights into retina's genetic code

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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