Molecular & Structural Biology

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Study provides new insights into how astrocytes help the brain process information

A collaboration between the laboratories of Vincent Bonin (NERF, empowered by VIB, imec and KU Leuven) and Matthew Holt (VIB-KU Leuven Center for Brain & Disease Research) reveals that noradrenaline plays a key role in how astrocytes - star-shaped cells in the brain closely associated with neurons - track distinct information during behavior.

12 Sep 2019

Scientists use CAR-T cells to reverse cardiac fibrosis

Scientists have used CAR-T cell therapy to treat cardiac fibrosis, a key part of heart disease and cardiac arrest.

12 Sep 2019

New technique for autonomous coordination of cell subpopulations

For years, scientists have explored ways to alter the cells of microorganisms in efforts to improve how a wide range of products are made - including medicines, fuels, and even beer.

12 Sep 2019

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

In this interview, Dr. Dave Fancy, CEO of Jackson ImmunoResearch explains how anti-VHH antibodies can be used to produce nanobodies and VHH libraries.

From Jackson ImmunoResearch Laboratories, Inc. 12 Sep 2019

Scientists identify molecule that plays key role in determining fate of cells under stress

St. Jude Children's Research Hospital scientists have identified a molecule that plays a pivotal role in determining the fate of cells under stress, much like a Roman emperor deciding the fate of gladiators in the coliseum.

12 Sep 2019

Gene coding error likely responsible for rare form of inherited 'short telomere' disease

By combing through the entire genetic sequences of a person with a lung scarring disease and 13 of the person’s relatives, Johns Hopkins Medicine researchers say they have found a coding error in a single gene that is likely responsible for a rare form of the disease and the abnormally short protective DNA caps on chromosomes long associated with it.

From Johns Hopkins Medicine 11 Sep 2019

YCC scientists uncover key to help treat many forms of cancer

Yale Cancer Center (YCC) scientists have uncovered the workings of a metabolic pathway or "gauge" that lets cancer cells detect when they have enough nutrients around them to grow.

11 Sep 2019

Brain circuit regulates individual responses to temptation cues, rat study finds

Differences in a key brain circuit may suggest why some individuals are less able than others to resist tempting cues, according to a study in rats published today in eLife.

11 Sep 2019

Salk researchers develop method to reveal epigenetic features of brain cells

The brain's prefrontal cortex, which gives us our ability to solve problems and plan ahead, contains billions of cells. But understanding the large diversity of cell types in this critical region, each with unique genetic and molecular properties, has been challenging.

10 Sep 2019

Key plant enzyme could pave way for development of medications and other products

Plants can do many amazing things. Among their talents, they can manufacture compounds that help them repel pests, attract pollinators, cure infections and protect themselves from excess temperatures, drought and other hazards in the environment.

8 Sep 2019

Lundbeck chooses Discngine’s 3decision platform for handling complex protein-ligand 3D structure data

Discngine, a software company specialized in developing applications for life sciences research, today announces that Lundbeck has selected its proprietary 3decision collaborative platform to manage the pharma company’s structural knowledge related to protein and ligand 3D structures.

5 Sep 2019

Researchers discover a molecule that regulates tumor development in different types of cancers

Researchers from the Josep Carreras Leukemia Research Institute, discover that a non-coding region of the genome originates a key molecule for the proliferation of tumors in breast cancer and some types of sarcoma.

5 Sep 2019

Scientists find receptor protein in the brain that promotes stress resilience

Scientists have discovered that a receptor on the surface of brain cells plays a key role in regulating how both animals and people respond to stress.

4 Sep 2019

Neurobiological pathophysiology of schizophrenia differs based on gender

The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study.

4 Sep 2019

MicroRNA methylation may be useful biomarker for early cancer diagnosis

Levels of molecules associated with genetic function, such as microRNA, can be an important indicator of abnormal activity associated with cancer. However, little is known about how different molecules are altered in cancerous cells.

4 Sep 2019

Breast cancer gene could be key to developing targeted therapy for hepatoblastoma

Hepatoblastoma is a rare form of liver cancer affecting just a few individuals per million. However, it is the leading cause of liver cancer in infants and young children, with most patients diagnosed before their third birthday.

4 Sep 2019

CRISPR-Cas9 successfully reverses type 2 diabetes in mice

Researchers have used CRISPR-Cas9 to treat obesity and type 2 diabetes in mice, a development that could eventually benefit humans.

3 Sep 2019

Study reshapes the understanding of telomerase's function in normal cells

New research from the University of Maryland and the National Institutes of Health reveals a new role for the enzyme telomerase.

3 Sep 2019

Large study quashes idea of “gay gene”

A vast new study including almost half a million people has concluded that no single gene is associated with same-sex behavior.

2 Sep 2019

SATI gene editing could replace CRISPR

Scientists have developed a new gene editing tool called SATI that is safer than CRISPR.

2 Sep 2019

Molecular & Structural Biology

Study provides new insights into how astrocytes help the brain process information

Scientists use CAR-T cells to reverse cardiac fibrosis

New technique for autonomous coordination of cell subpopulations

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

Scientists identify molecule that plays key role in determining fate of cells under stress

Gene coding error likely responsible for rare form of inherited 'short telomere' disease

YCC scientists uncover key to help treat many forms of cancer

Brain circuit regulates individual responses to temptation cues, rat study finds

Salk researchers develop method to reveal epigenetic features of brain cells

Key plant enzyme could pave way for development of medications and other products

Lundbeck chooses Discngine’s 3decision platform for handling complex protein-ligand 3D structure data

Researchers discover a molecule that regulates tumor development in different types of cancers

Scientists find receptor protein in the brain that promotes stress resilience

Neurobiological pathophysiology of schizophrenia differs based on gender

MicroRNA methylation may be useful biomarker for early cancer diagnosis

Breast cancer gene could be key to developing targeted therapy for hepatoblastoma

CRISPR-Cas9 successfully reverses type 2 diabetes in mice

Study reshapes the understanding of telomerase's function in normal cells

Large study quashes idea of “gay gene”

SATI gene editing could replace CRISPR

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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