Molecular & Structural Biology

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Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

An international team coordinated by the Interdisciplinary Research Structure in Biotechnology and Biomedicine of the University of Valencia has proved how the folding of membrane proteins begins before they are inserted into biological membranes, a fact that has been central to the biochemical research for decades.

19 Dec 2018

Study investigates why mammals' sense of smell deteriorates in old age

As mammals age, their sense of smell deteriorates. In a study published in the journal 'Cell Reports', an interdisciplinary research team at Helmholtz Zentrum München and the University Medical Centre Mainz investigated why this is the case.

19 Dec 2018

DNA “webs” shown to promote metastasis in ovarian cancer

Researchers have found that neutrophils cast DNA “webs” that aid the spread of ovarian cancer cells to new tissues (a process known as metastasis).

19 Dec 2018

University of Marburg team celebrates success at 2018 IGEM Giant Jamboree competition

At the 2018 iGEM Gaint Jamboree, the team of the University of Marburg won the Grand Prize in the overgraduate section with their project “VibriGens – Accelerating SynBio”. At the end of October the team received its award in Boston, USA.

From BMG LABTECH GmbH 19 Dec 2018

Developing the Next Generation of Water-soluble DREADDs

An interview with James Flanaghan, discussing the uses of DREADDs in neurobiological research and the advantages of water-soluble ligands.

From Hello Bio 19 Dec 2018

Novel insight on inflammatory regulation could pave way for effective pain therapies

A novel way in which the inflammatory response to pain is regulated has been described in the open-access journal eLife.

19 Dec 2018

Researchers discover how MAPK translocation leads to drug resistance in melanoma

Researchers have discovered that the ER translocation of MAPK leads to drug resistance in melanoma.

18 Dec 2018

Neuroscience-protein that creates borders inside the brain

Boundaries between different regions of the brain are essential for the brain to function. Research to-date has shown that molecular machineries located at the cell membrane such as cell adhesion molecules are responsible for regulating the boundary formation.

18 Dec 2018

Researchers propose new model to explain how neural networks communicate

The brain is organized into a network of specialized networks of nerve cells. For such a brain architecture to function, these specialized networks - each located in a different brain area - need to be able to communicate with each other.

17 Dec 2018

Inflating cells to analyze organelle structure and function

Researchers have developed a technique that enables visualization of cellular organelles at a resolution that has not previously been achievable in optical microscopy.

17 Dec 2018

New robust method for microscopically profiling tiny single cells

Many of the cell types in our bodies work in obscure ways, that science does not yet fully understand. That also goes for immune cells, which are vital for protecting us against serious diseases.

17 Dec 2018

RNA sequencing offers novel insights into the microbiome

Researchers have come up with a revolutionary strategy for studying the activity of the gut microbiome – using high-throughput sequencing of tRNA.

17 Dec 2018

A Story of Innovative Molecules: From Machines to Cyclic Compounds

2016 Nobel Laureate in Chemistry Fraser Stoddart outlines his research involving mechanically interlocked molecules and molecular machines, and introduces the work of some of the students in his lab, to be discussed at Pittcon 2018.

From Pittcon 17 Dec 2018

Researchers reveal how key transcription factor keeps the immune system in check

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end up harming healthy tissues.

17 Dec 2018

Getting the Most Out of the CLARITY Technique

An interview with Dr. Tim Steppe, discussing the latest advances in the CLARITY technique and his top tips for scientists using this method in their research.

From Logos Biosystems 17 Dec 2018

Researchers uncover microRNAs involved in the control of social behavior

The recent discovery of microRNAs as key regulators of biological processes has fueled an explosion of research activity into their function in health and disease.

14 Dec 2018

Geneticists discover how sex-linked disorders arise

Researchers have discovered a regulatory gene carried on the Y chromosome that determines whether a baby will be male or female and the risk of disease.

14 Dec 2018

Researchers reveal brain mechanism that drives itch-evoked scratching behavior

It's a maddening cycle that has affected us all: it starts with an itch that triggers scratching, but scratching only makes the itchiness worse.

14 Dec 2018

Parents and infants show similar brain activity when they play together, study shows

When infants are playing with objects, their early attempts to pay attention to things are accompanied by bursts of high-frequency activity in their brain.

14 Dec 2018

Exercise-induced hormone activates cells critical for bone remodeling in mice

Exercise has been touted to build bone mass, but exactly how it actually accomplishes this is a matter of debate. Now, researchers show that an exercise-induced hormone activates cells that are critical for bone remodeling in mice.

14 Dec 2018

Molecular & Structural Biology

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

Study investigates why mammals' sense of smell deteriorates in old age

DNA “webs” shown to promote metastasis in ovarian cancer

University of Marburg team celebrates success at 2018 IGEM Giant Jamboree competition

Developing the Next Generation of Water-soluble DREADDs

Novel insight on inflammatory regulation could pave way for effective pain therapies

Researchers discover how MAPK translocation leads to drug resistance in melanoma

Neuroscience-protein that creates borders inside the brain

Researchers propose new model to explain how neural networks communicate

Inflating cells to analyze organelle structure and function

New robust method for microscopically profiling tiny single cells

RNA sequencing offers novel insights into the microbiome

A Story of Innovative Molecules: From Machines to Cyclic Compounds

Researchers reveal how key transcription factor keeps the immune system in check

Getting the Most Out of the CLARITY Technique

Researchers uncover microRNAs involved in the control of social behavior

Geneticists discover how sex-linked disorders arise

Researchers reveal brain mechanism that drives itch-evoked scratching behavior

Parents and infants show similar brain activity when they play together, study shows

Exercise-induced hormone activates cells critical for bone remodeling in mice

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Empowering genomics research with cloud-based innovation

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