Molecular & Structural Biology

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Japanese researchers develop highly sensitive method to detect potential cancer biomarker

Exosomes regulate intercellular communication in cancers, and are drawing attention as a potential cancer biomarker. A Japanese research group has developed a highly sensitive method for detecting these exosomes that could potentially contribute to early detection of cancer.

31 Jan 2019

Researchers discover how transcription factors find specific loci within DNA

Bioengineering experts have discovered that transcription factors which bind non-specifically to mitotic chromosomes are more efficient at finding their binding site within DNA during interphase.

30 Jan 2019

Dietary fiber polymers can influence gut environment through physical forces

Large molecules from dietary fiber, called polymers, can physically influence the environment in the small intestine by causing solid particles to group together (or aggregate), according to research published in eLife.

30 Jan 2019

Genetics determine whether you are an early riser or a night owl

An international study has shed light on how the genetics behind the human body clock may be linked to mental health and disease.

29 Jan 2019

Research provides new understanding of genome regulation in early life

After the fertilization of an egg cell, two become one; two sets of genetic information combine to form a genome. We can think of the egg and sperm as information capsules with stored instructions for starting a new life, but post fertilization, what kick starts the interpretation of these instructions?

29 Jan 2019

Researchers develop powerful new tool to create concrete cortical blueprint

With a bit of light, a few photo sensitive compounds and specialized paper, the blueprint was born. As the favored type of technical drawing for over a century, architects used this crucial tool for its fast reproducibility as well as its capacity for detailed documentation.

29 Jan 2019

Genetic testing to be provided by the NHS in exchange for genomic data

The NHS is going to start providing genetic tests in exchange for patients in England who agree to share their genomic data so that it can be used for research.

28 Jan 2019

Leica Microsystems' new THUNDER imagers set to transform visualization of 3D samples

World-leading designer and manufacturer of innovative microscope solutions, Leica Microsystems, has announced the launch of a new class of instruments for high-speed, high-quality imaging of a large diversity of samples, including thick specimens.

From Leica Microsystems GmbH 28 Jan 2019

Researchers create synthetic growth factor that offers comparable biological response

Growth factors are ligands that play important roles in the body - they are responsible for tissue regeneration, wound healing, and the maintenance and growth of cells.

28 Jan 2019

Scientists use integrative approach to study how COQ9 binds and interacts with lipids

The synthesis and transport of biological lipids across the mostly water-filled interior of the cell is a longstanding problem in biology.

28 Jan 2019

New lessons learned from adult neurogenesis debate

Since the 1960s, consensus about whether human adults generate new neurons with age has swayed back and forth from "yes, at least in some places in the brain" to "no, not at all."

25 Jan 2019

Studies show broad benefits of rocking motion during sleep

Anyone who has ever put a small child to bed or drifted off in a gently swaying hammock will know that a rocking motion makes getting to sleep seem easier.

25 Jan 2019

Scientists develop new method for synthesizing para-carboxyplenylsiloxanes

Russian scientists have developed a new method for synthesizing para-carboxyplenylsiloxanes, a unique class of organosilicon compounds. The resulting compounds are promising for creating self-healing, electrically conductive, heat- and frost-resistant silicones.

25 Jan 2019

Newly developed algorithms can predict and correct errors in single cell analyses

Modern technology makes it possible to sequence individual cells and to identify which genes are currently being expressed in each cell.

24 Jan 2019

Researchers reveal important signaling pathway in breast cancer

Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences of the United States of America that a particular signaling pathway in breast-cancer tumors causes cancer cells to divide symmetrically, expanding the tumor. Inhibiting the pathway by drugs could become a strategy for eliminating the cancer cells.

24 Jan 2019

Researchers uncover new role of heterochromatin in maintaining chromosomal integrity

Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes in the structure of chromosomes, known as gross chromosomal rearrangements, can result in cell death or genetic diseases such as cancer.

24 Jan 2019

Enzyme that breaks down amino acids plays key role in promoting cellular senescence

Permanently arrested cell growth is known as "cellular senescence", and the accumulation of senescent cells may be one cause of aging in our bodies. Japanese researchers have discovered that a certain enzyme in our bodies promotes cellular senescence by producing reactive oxygen species.

24 Jan 2019

Molecular & Structural Biology

Japanese researchers develop highly sensitive method to detect potential cancer biomarker

Researchers discover how transcription factors find specific loci within DNA

Dietary fiber polymers can influence gut environment through physical forces

Genetics determine whether you are an early riser or a night owl

Research provides new understanding of genome regulation in early life

Researchers develop powerful new tool to create concrete cortical blueprint

Genetic testing to be provided by the NHS in exchange for genomic data

Leica Microsystems' new THUNDER imagers set to transform visualization of 3D samples

Researchers create synthetic growth factor that offers comparable biological response

Scientists use integrative approach to study how COQ9 binds and interacts with lipids

New lessons learned from adult neurogenesis debate

Studies show broad benefits of rocking motion during sleep

Scientists develop new method for synthesizing para-carboxyplenylsiloxanes

Newly developed algorithms can predict and correct errors in single cell analyses

Researchers reveal important signaling pathway in breast cancer

Researchers uncover new role of heterochromatin in maintaining chromosomal integrity

Enzyme that breaks down amino acids plays key role in promoting cellular senescence

Study reveals how staying in shape is crucial for reproductive success of cells

LJI awarded $22 million contract renewal to host and expand Immune Epitope Database

Old oligodendrocytes can repair damage in the brains of patients with multiple sclerosis

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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