Molecular & Structural Biology

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ATLAS assay reveals SARS-CoV-2 variant T-cell responses

Researchers utilize the ATLAS screening assay to reveal the antigen response profiles of T-cells to different SARS-CoV-2 variants.

23 May 2022

Study demonstrates how the transcription factor C/EBPβ can positively influence fat storage

The chronic nutritional and metabolic disease of obesity is characterized by an excessive increase in body fat and its accumulation in tissues.

20 May 2022

Plastins may promote disease when they act like workaholics and disrupt cellular environment

A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.

19 May 2022

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Researchers analyze the mechanisms by which two SARS-CoV-2 accessory proteins, ORF3a and ORF7a, can downregulate the expression of MHC-I.

19 May 2022

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

Researchers predict structure models of the full-length SARS-CoV-2 N protein in both the presence and absence of RNA.

19 May 2022

A review on the hallmarks of cancer and aging

Dr. Mikhail Blagosklonny published his new review paper in Aging (Aging-US) Volume 14, Issue 9, entitled, "Hallmarks of cancer and hallmarks of aging."

18 May 2022

Molecular pathway allows cells to sense when their lipid supplies become depleted

UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation.

18 May 2022

Tabula sapiens, most comprehensive human cell atlas

In a recent study published in the journal Science, researchers created an atlas termed the Tabula sapiens for over 400 distinct cell types of humans. Several aspects of human physiology were revealed by the atlas, such as how different types of cells splice genes differently.

16 May 2022

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

In a recent study posted to the bioRxiv* pre-print server, researchers characterized the mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 15 (Nsp-15).

16 May 2022

New discovery has potential to stop inflammation at the "growing end"

Redness, swelling, pain - these are signs of inflammation. It serves to protect the body from pathogens or foreign substances.

13 May 2022

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain — a series of protein complexes essential for a cellular respiration and energy production — is necessary for the activation of another protein complex linked to inflammation and the progression of chronic diseases, according to a study published in Nature Immunology.

12 May 2022

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

In health care, perhaps no word sends a more chilling message than "cancer." Brain tumors, for example, prove especially resistant to current treatments. Only 5% of patients with that condition survive more than three years and the median survival time is 10 to 14 months.

12 May 2022

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

An article published in the journal Molecular Psychiatry reveals the molecular mechanisms to explain how the YWHAZ gene –related to psychiatric and neurological disorders such as autism and schizophrenia– can alter the neurodevelopmental process.

10 May 2022

UCLouvain discovery could counter SARS-CoV-2 virus independently of the mutations

Despite the effectiveness of vaccination campaigns worldwide, the threat posed by Covid-19 still exists. First of all, a new SARS-CoV-2 variant could very well emerge that may not respond to current vaccines.

10 May 2022

Better understanding of hybrid parasite strains could improve Chagas disease diagnosis

Researchers at Karolinska Institutet in Sweden have mapped how the parasite Trypanosoma cruzi forms new variants that are more effective at evading the immune system and causing disease.

10 May 2022

Using virtual reality headsets to instruct UTSA students about protein structures

Francis Yoshimoto, assistant professor in the UTSA College of Sciences' Department of Chemistry, is introducing his Biochemistry II laboratory students to a new way of learning - using virtual reality headsets to observe and analyze protein structures.

10 May 2022

Gene therapy effectively reduces neuropathic pain in mice with spinal cord injuries

An international team of researchers, led by scientists at University of California San Diego School of Medicine, report that a gene therapy that inhibits targeted nerve cell signaling effectively reduced neuropathic pain with no detectable side effects in mice with spinal cord or peripheral nerve injuries.

9 May 2022

Love is in the air...detected by PTR-TOF

Scientists from the German Max Planck Gesellschaft found out that a characteristic signature of volatile molecules is found in the breath of sexually aroused people. The test subjects exhaled less isoprene and carbon dioxide, while the concentration of degradation products of certain neurotransmitters increased.

From Ionicon Analytik Ges.m.b.H. 9 May 2022

Mitosis in moss plants could be far more similar to animal cell division than previously thought

For a new plant to grow from a seed, cells need to divide numerous times. Daughter cells can each take on different tasks and sometimes vary in size. How plants determine the plane of cell division in this process, known as mitosis, is being researched by Prof. Dr. Ralf Reski and Dr. Elena Kozgunova from the University of Freiburg in a joint effort with Prof. Dr. Gohta Goshima from Nagoya University.

6 May 2022

Applying a form of AI to sift through large amounts of biological data

Researchers at the University of Missouri are applying a form of artificial intelligence (AI) - previously used to analyze how National Basketball Association (NBA) players move their bodies - to now help scientists develop new drug therapies for medical treatments targeting cancers and other diseases.

6 May 2022

Molecular & Structural Biology

ATLAS assay reveals SARS-CoV-2 variant T-cell responses

Study demonstrates how the transcription factor C/EBPβ can positively influence fat storage

Plastins may promote disease when they act like workaholics and disrupt cellular environment

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

A review on the hallmarks of cancer and aging

Molecular pathway allows cells to sense when their lipid supplies become depleted

Tabula sapiens, most comprehensive human cell atlas

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

New discovery has potential to stop inflammation at the "growing end"

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

UCLouvain discovery could counter SARS-CoV-2 virus independently of the mutations

Better understanding of hybrid parasite strains could improve Chagas disease diagnosis

Using virtual reality headsets to instruct UTSA students about protein structures

Gene therapy effectively reduces neuropathic pain in mice with spinal cord injuries

Love is in the air...detected by PTR-TOF

Mitosis in moss plants could be far more similar to animal cell division than previously thought

Applying a form of AI to sift through large amounts of biological data

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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