Molecular & Structural Biology

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Researchers create detailed molecular atlas of fetal development of the brain

Researchers at Karolinska Institutet in Sweden have developed a detailed molecular atlas of the fetal development of the brain.

28 Jul 2021

Study: All GA-binding proteins have the highest expression levels in secondary glioblastomas

Oncotarget published "TERT and its binding protein: overexpression of GABPA/B in high grade gliomas" which reported that all GA-binding proteins progress through the glioma grades and have the highest expression levels in secondary glioblastomas.

28 Jul 2021

Research provides insights into how the hippocampus contributes to memory storage in the cortex

A new MIT study of how a mammalian brain remembers what it sees shows that while individual images are stored in the visual cortex, the ability to recognize a sequence of sights critically depends on guidance from the hippocampus, a deeper structure strongly associated with memory but shrouded in mystery about exactly how.

27 Jul 2021

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Researchers from the Institute of Process Engineering of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

26 Jul 2021

Novel microfluidic device used to manipulate major whey protein

After gaining world attention by 'unboiling' egg protein, Flinders University scientists have now used an Australian-made novel thin film microfluidic device to manipulate Beta-lactoglobulin (β-lactoglobulin), the major whey protein in cow's, sheep's and other mammals.

26 Jul 2021

Researchers investigate brain responses to aesthetically appealing natural landscapes

How does a view of nature gain its gloss of beauty? We know that the sight of beautiful landscapes engages the brain's reward systems.

23 Jul 2021

Brain's "feel good" chemical messenger can be willfully manipulated, study shows

From the thrill of hearing an ice cream truck approaching to the spikes of pleasure while sipping a fine wine, the neurological messenger known as dopamine has been popularly described as the brain's "feel good" chemical related to reward and pleasure.

23 Jul 2021

Scientists uncover the early assembly of gamma-secretase involved in plaque production

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease.

23 Jul 2021

Llama ‘nanobodies’ have the potential to outwit human cytomegalovirus

Scientists have developed a 'nanobody' - a small fragment of a llama antibody - that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system.

22 Jul 2021

Researchers identify immune protein linked to rare neurodegenerative disease

UT Southwestern researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C.

21 Jul 2021

Scientists seek to block pathogen’s most reliable weapon to cause severe malaria

The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.

21 Jul 2021

IgA deficiency results in substantial intestinal inflammation, study reveals

While researchers have known for years that immunoglobulin A (IgA) is important for gut health, it has remained unclear exactly what role it plays in preventing infection and disease. But now, researchers from Japan have found that eliminating IgA disrupts the balance of the intestinal ecosystem, making it susceptible to disease.

20 Jul 2021

Scientists identify key role of p38-MK2 pathway in determining cell fate in response to stress

Living organisms are often exposed to stress stimuli generated either by external or internal factors, and they need to respond accordingly.

20 Jul 2021

Protein consumption at breakfast can increase muscle size and function, finds study

Proteins constitute an essential dietary component that help in the growth and repair of the body. Composed of long chains of amino acids, proteins promote the growth of skeletal muscles, the group of muscles that help us move.

20 Jul 2021

Chemical modification in RNA molecules may offer protection against liver disease

A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells' protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver and can lead to advanced liver disease, according to a new study by UCLA researchers.

19 Jul 2021

Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication

In February 2020, a trio of bio-imaging experts were sitting amiably around a dinner table at a scientific conference in Washington, D.C., when the conversation shifted to what was then a worrying viral epidemic in China.

19 Jul 2021

Central amygdala micro-circuits play active role in regulation of fear responses

The brain mechanisms underlying the suppression of fear responses have attracted a lot of attention as they are relevant for therapy of human anxiety disorders.

16 Jul 2021

Research shows a direct link between SUV39H2 gene and autism spectrum disorders

New research from the RIKEN Center for Brain Science in Japan shows that a deficit in histone methylation could lead to the development of autism spectrum disorders (ASD).

16 Jul 2021

Virginia Tech researchers receive $2.7 million grant to study mosquito's biological timing

Mosquitoes may be small, but they are a formidable foe. Not only can they smell over 400 chemicals that we emit and detect the carbon dioxide we breathe out, but they can even adapt their daily behavior in response to our own.

16 Jul 2021

New live cell models lay the groundwork for studies into mitochondrial diseases

The mitochondrion has garnered quite the reputation for its role as the "powerhouse of the cell." These tiny, but mighty organelles play various life-sustaining roles, from powering our own cells and organs to fueling chemical and biological processes.

15 Jul 2021

Molecular & Structural Biology

Researchers create detailed molecular atlas of fetal development of the brain

Study: All GA-binding proteins have the highest expression levels in secondary glioblastomas

Research provides insights into how the hippocampus contributes to memory storage in the cortex

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Novel microfluidic device used to manipulate major whey protein

Researchers investigate brain responses to aesthetically appealing natural landscapes

Brain's "feel good" chemical messenger can be willfully manipulated, study shows

Scientists uncover the early assembly of gamma-secretase involved in plaque production

Llama ‘nanobodies’ have the potential to outwit human cytomegalovirus

Researchers identify immune protein linked to rare neurodegenerative disease

Scientists seek to block pathogen’s most reliable weapon to cause severe malaria

IgA deficiency results in substantial intestinal inflammation, study reveals

Scientists identify key role of p38-MK2 pathway in determining cell fate in response to stress

Protein consumption at breakfast can increase muscle size and function, finds study

Chemical modification in RNA molecules may offer protection against liver disease

Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication

Central amygdala micro-circuits play active role in regulation of fear responses

Research shows a direct link between SUV39H2 gene and autism spectrum disorders

Virginia Tech researchers receive $2.7 million grant to study mosquito's biological timing

New live cell models lay the groundwork for studies into mitochondrial diseases

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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