Molecular & Structural Biology

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NYU Abu Dhabi researchers use NMR spectroscopy to map the structure of specific nanobody

For the first time in the UAE, researchers at NYU Abu Dhabi have used nuclear magnetic resonance techniques to determine the structure of a specific nanobody, Nb23, potentially leading to a better understanding of how this small protein derived from an antibody type, found only in camelids (i.e camels, llamas, and alpacas) and sharks, can fight diseases ranging from rheumatoid arthritis, lupus and psoriasis to lymphoma and breast cancer.

2 Jul 2021

RNA-binding proteins represent a new class of drug targets for triple-negative breast cancer

In cancer research, it's a common goal to find something about cancer cells -- some sort of molecule -- that drives their ability to survive, and determine if that molecule could be inhibited with a drug, halting tumor growth. Even better: The molecule isn't present in healthy cells, so they remain untouched by the new therapy.

2 Jul 2021

New open-source camera system captures the mouse's view of natural environment

Researchers based in Munich and Tuebingen have developed an open-source camera system that images natural habitats as they appear to rodents.

2 Jul 2021

Researchers introduce novel type of click reaction for living cells and organisms

Increasing our understanding of cellular processes requires information about the types of biomolecules involved, their locations, and their interactions.

2 Jul 2021

Researchers reveal a promising target for designing anti-cancer therapies

Chances are, every one of us has been affected by cancer in one way or another. Unlike some other deadly diseases, cancer can take many forms inside the human body, so learning more about a single enzyme linked to many types of this disease could lead to more effective treatments.

2 Jul 2021

Researchers evaluate tools for identification of microRNAs in plants

Almost twenty years ago, the process of RNA silencing was discovered in plants, whereby small fragments of RNA inactivate a portion of a gene during protein synthesis.

1 Jul 2021

Study offers clues for earlier diagnosis of folate deficiency

As many expectant mothers know, getting enough folate is key to avoiding neural tube defects in the baby during pregnancy. But for the individuals who carry certain genetic variants, dealing with folate deficiency can be a life-long struggle which can lead to serious neurological and heart problems and even death.

1 Jul 2021

New method to transport RNA-based drugs to subpopulation of immune cells

Tel Aviv University's groundbreaking technology may revolutionize the treatment of cancer and a wide range of diseases and medical conditions. In the framework of this study, the researchers were able to create a new method of transporting RNA-based drugs to a subpopulation of immune cells involved in the inflammation process, and target the disease-inflamed cell without causing damage to other cells.

30 Jun 2021

Novel approach to molecular drug design paves way for promising bladder cancer therapy

A new approach to molecular drug design has yielded a highly promising bladder cancer drug, which induced rapid shedding of tumor cells and resulted in a significant reduction in tumour size when used in clinical trials.

28 Jun 2021

Discovery opens door to new diagnostics and therapeutic strategies for male infertility

Scientists at The University of Toledo discovered new movement in sperm that provides innovative avenues for diagnostics and therapeutic strategies for male infertility.

28 Jun 2021

Understanding new resting phase of stem cells could help put glioma tumors to sleep

Christopher Plaisier, an assistant professor of biomedical engineering in the Ira A. Fulton Schools of Engineering at Arizona State University, and Samantha O'Connor, a biomedical engineering doctoral student in the Plaisier Lab, are leading research into a new stage of the stem cell life cycle that could be the key to unlocking new methods of brain cancer treatment.

25 Jun 2021

Structural studies of SARS-CoV-2 spike protein reveal new properties of Alpha and Beta variants

New SARS-CoV-2 variants are spreading rapidly, and there are fears that current COVID-19 vaccines won't protect against them.

25 Jun 2021

Researchers determine molecular structure of bacterial protein complex critical for tuberculosis

Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a major threat to global health security, and has been declared by the World Health Organization as a global health emergency.

25 Jun 2021

Molecular & Structural Biology

NYU Abu Dhabi researchers use NMR spectroscopy to map the structure of specific nanobody

RNA-binding proteins represent a new class of drug targets for triple-negative breast cancer

New open-source camera system captures the mouse's view of natural environment

Researchers introduce novel type of click reaction for living cells and organisms

Researchers reveal a promising target for designing anti-cancer therapies

Researchers evaluate tools for identification of microRNAs in plants

Study offers clues for earlier diagnosis of folate deficiency

New method to transport RNA-based drugs to subpopulation of immune cells

Novel approach to molecular drug design paves way for promising bladder cancer therapy

Discovery opens door to new diagnostics and therapeutic strategies for male infertility

Understanding new resting phase of stem cells could help put glioma tumors to sleep

Structural studies of SARS-CoV-2 spike protein reveal new properties of Alpha and Beta variants

Researchers determine molecular structure of bacterial protein complex critical for tuberculosis

Surprising similarities found in membrane proteins of bacteria and humans

Researchers identify key role of enzyme essential for invasion of the toxoplasmosis parasite

Researchers identify a new type of odor neuron in flies

Increasing novel lncRNA in cardiomyocytes can inhibit the progression of heart failure

Researchers unravel new mechanism that enables cancer development

Heidelberg researchers replicate rare genetic defect in fish model

Protein blueprint may aid in treatments for infertility and help protect future fertility

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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