Pharmaceutical News

RSS

Five important questions about Pfizer’s COVID-19 vaccine

Pfizer's announcement on Monday that its COVID-19 shot appears to keep nine in 10 people from getting the disease sent its stock price rocketing. Many news reports described the vaccine as if it were our deliverance from the pandemic, even though few details were released.

11 Nov 2020

Service requests to city telephone lines can help identify "hotspots" for opioid overdose

Service requests to city non-emergency telephone lines can help identify "hotspots" for opioid use and overdoses, a study in Columbus found.

11 Nov 2020

Study: Effect of diabetes medication can be blocked by a molecule from gut bacteria

The action of metformin, the classic drug used to treat diabetes by stabilizing blood sugar, can be blocked by a molecule from the bacteria in our intestines, a University of Gothenburg study shows.

11 Nov 2020

Immunotherapy drugs trigger inflammatory arthritis in subset of cancer patients

Since doctors began treating cancer patients with immunotherapy drugs called checkpoint inhibitors nearly a decade ago, they have observed that a subset of these patients experience a side effect that clinically looks like inflammatory arthritis.

10 Nov 2020

Insilico signs multi-target drug discovery agreement with Janssen Pharmaceutica

Insilico Medicine, a leader in deep generative reinforcement learning for target discovery, small molecule generation, and prediction of clinical trial outcomes, today announced that it entered into a multi-target drug discovery agreement with Janssen Pharmaceutica N.V. (Janssen).

10 Nov 2020

Study shows dexamethasone can reduce chance of COVID-19-related death

Research has shown that dexamethasone, a widely available steroid, can significantly reduce the chance of death from COVID-19.

10 Nov 2020

Search for a snakebite drug might lead to a COVID treatment, too

Dr. Matthew Lewin, founder of the Center for Exploration and Travel Health at the California Academy of Sciences, was researching snakebite treatments in rural locations in preparation for an expedition to the Philippines in 2011.

9 Nov 2020

Centhaquine drug improves outcomes, reduces death rate in patients with severe blood or fluid loss

Centhaquine, a new medication to treat patients who have severe blood or fluid loss, significantly improved outcomes and reduced death rate when added to standard of care, compared to standard care alone, according to preliminary research to be presented at the American Heart Association's Resuscitation Science Symposium 2020.

9 Nov 2020

Study: Hydroxychloroquine has no effect on abnormal heart rhythm in lupus patients with CKD

New research shows that adults with lupus who take the antimalarial drug, hydroxychloroquine, do not have any differences in their corrected QT (QTc) intervals, an electrocardiogram (EKG) measurement of the heart's electrical signals, even if they have chronic kidney disease (CKD), a complication of lupus that can be associated with increased levels of the medication.

9 Nov 2020

New strategy for designing COVID-19 antiviral drugs to inhibit key viral protein

SARS-CoV-2, the respiratory virus that causes COVID-19, attacks the body in multiple steps. Gaining entry into cells deep within the lungs and hijacking the human host cell's machinery to churn out copies of itself are two of the earliest steps -- both essential for viral infection.

9 Nov 2020

RA guidelines stress on minimizing steroids and maximizing methotrexate, biologics

The American College of Rheumatology (ACR) will preview its 2020 Guideline for the Management of Rheumatoid Arthritis (RA) at ACR Convergence, the ACR's annual meeting. The comprehensive, clinical recommendations for pharmacologic treatment of RA includes important updates to the previous guideline released in 2015.

9 Nov 2020

FDA releases final guidance to help identify and prevent insanitary conditions at compounders’ facilities

Protecting patients from exposure to poor quality compounded drugs is a fundamental part of the U.S. Food and Drug Administration's drug compounding program, and we are committed to protecting patients.

6 Nov 2020

Patients with rheumatic diseases reported antimalarial drug shortages during COVID-19

A new study shows that patients with rheumatic diseases across Africa, Southeast Asia, the Americas and Europe had trouble filling their prescriptions of antimalarial drugs, including hydroxychloroquine, during the 2020 global coronavirus pandemic, when antimalarials were touted as a possible COVID-19 treatment.

6 Nov 2020

Hydroxychloroquine not associated with prolonged heart rhythm intervals in RA or lupus patients

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, discovers that use of hydroxychloroquine, a generic drug, does not cause any significant differences in QTc length or prolonged QTc, key measures of heart rate, in people with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE).

6 Nov 2020

Oral methotrexate can be an effective intervention for people with knee OA

A new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of treatment with oral methotrexate, adults with primary knee osteoarthritis (OA) with inflammation had significant improvements in physical function and inflammation, a sign that this inexpensive, generic pill may be an important intervention for knee OA.

6 Nov 2020

TB screening needed for people on methotrexate who live in at-risk areas

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that tuberculosis (TB) screening and ongoing clinical care is needed for people on methotrexate who live in areas where the highly infectious illness is common.

6 Nov 2020

Osteoporosis drug increases bone mineral density in the hip and lumbar spine

New research presented at ACR Convergence, the American College Rheumatology's annual meeting, reveals that romosozumab, an osteoporosis drug, produces substantial gains in bone mineral density in the hip and lumbar spine within one year, and that transitioning patients to a potent antiresorptive drug can lead to even more bone density gains.

6 Nov 2020

Commonly prescribed anti-depressant may halt the growth of childhood sarcoma

A new study has found that a commonly prescribed anti-depressant may halt growth of a type of cancer known as childhood sarcoma, at least in mice and laboratory cell experiments.

6 Nov 2020

Researchers develop novel chemo-immunotherapy agent to treat pancreatic tumors

Pancreatic cancer is highly lethal: according to the National Cancer Institute, only about 10 percent of patients remain alive five years after diagnosis.

6 Nov 2020

New resource can help predict drug sensitivity and optimize therapeutic strategies

Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms and to identify optimal combination treatment strategies.

6 Nov 2020

Pharmaceutical News

Five important questions about Pfizer’s COVID-19 vaccine

Service requests to city telephone lines can help identify "hotspots" for opioid overdose

Study: Effect of diabetes medication can be blocked by a molecule from gut bacteria

Immunotherapy drugs trigger inflammatory arthritis in subset of cancer patients

Insilico signs multi-target drug discovery agreement with Janssen Pharmaceutica

Study shows dexamethasone can reduce chance of COVID-19-related death

Search for a snakebite drug might lead to a COVID treatment, too

Centhaquine drug improves outcomes, reduces death rate in patients with severe blood or fluid loss

Study: Hydroxychloroquine has no effect on abnormal heart rhythm in lupus patients with CKD

New strategy for designing COVID-19 antiviral drugs to inhibit key viral protein

RA guidelines stress on minimizing steroids and maximizing methotrexate, biologics

FDA releases final guidance to help identify and prevent insanitary conditions at compounders’ facilities

Patients with rheumatic diseases reported antimalarial drug shortages during COVID-19

Hydroxychloroquine not associated with prolonged heart rhythm intervals in RA or lupus patients

Oral methotrexate can be an effective intervention for people with knee OA

TB screening needed for people on methotrexate who live in at-risk areas

Osteoporosis drug increases bone mineral density in the hip and lumbar spine

Commonly prescribed anti-depressant may halt the growth of childhood sarcoma

Researchers develop novel chemo-immunotherapy agent to treat pancreatic tumors

New resource can help predict drug sensitivity and optimize therapeutic strategies

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Latest News