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New review focuses on the structure-activity relationships of flavonoids

ABCB1 in the ABC transporter family also termed as P-glycoprotein, grants the simultaneous resistance of metastatic cancer cells towards various anti-cancer drugs with different targets and diverse chemical structures.

27 Dec 2018

Breast cancer drugs could tackle lung cancers resistant to targeted therapies

A class of drugs used to treat certain breast cancers could help to tackle lung cancers that have become resistant to targeted therapies, suggests a new study in mice from the Francis Crick Institute and the Institute of Cancer Research.

27 Dec 2018

Study: Reactivation of HIV-infected cells depends on its size and cell cycle

Thanks to the development of antiretroviral drugs, human immunodeficiency virus is considered a manageable chronic disease today.

27 Dec 2018

Lupin partners with Abbvie to develop and commercialize new targeted oncology treatments

Pharma major Lupin Limited and global biopharmaceutical company AbbVie Inc., today announced that AbbVie has licensed Lupin's MALT1 (Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1) inhibitor program.

25 Dec 2018

Statins reduce the formation of brown adipose tissue

A certain proportion of the adult population has not only white adipose (or fatty) tissue, but also the brown kind. This brown adipose tissue helps to convert sugar and fat into heat. People with brown adipose tissue are better at regulating their body temperature in the winter, and are less likely to suffer from excess weight or diabetes.

21 Dec 2018

New treatment for adults with rare, life-threatening blood disease receives FDA approval

The U.S. Food and Drug Administration today approved Ultomiris (ravulizumab) injection for the treatment of adult patients with paroxysmal nocturnal hemoglobinuria (PNH), a rare and life-threatening blood disease.

21 Dec 2018

Study shows high rates of antibiotic overuse in patients undergoing common urological procedures

A new study suggests that antibiotics are being overused in up to 60 percent of patients undergoing common urological procedures.

21 Dec 2018

FDA approves new treatment for rare disease of the bone marrow and blood

The U.S. Food and Drug Administration today approved Elzonris (tagraxofusp-erzs) infusion for the treatment of blastic plasmacytoid dendritic cell neoplasm in adults and in pediatric patients, two years of age and older.

21 Dec 2018

Combination of statins and Mediterranean diet more effective in reducing cardiovascular mortality risk

For those who have already had a heart attack or a stroke, the combination of statins and Mediterranean Diet appears to be the most effective choice to reduce the risk of mortality, especially from cardiovascular causes.

21 Dec 2018

Bacterial resistance to last-resort antibiotic is spreading at alarming rate in Vietnam

Researchers have discovered that polymyxin E-resistant Escherichia coli is widely prevalent among people living in rural Vietnam.

21 Dec 2018

Scientists develop novel eye drop that reduces sight-threatening scarring to the eye surface

Scientists at the University of Birmingham have developed a novel eye drop that rapidly reduces sight-threatening scarring to the surface of the eye.

21 Dec 2018

Study provides information about chemotherapeutic drugs binding to plasma proteins

Chemotherapy is use of drugs to cure a disease but more specifically, it refers to drug therapy for cancer. Cancer chemotherapy can be done with a single drug or a combination of drugs and is usually systematic in nature, that is to say that a drug is administered through the blood circulation to eliminate cancer cells in many parts of the body.

21 Dec 2018

Experts in Parkinson's research propose roadmap for drug trials targeting alpha-synuclein

A recently discovered protein, alpha-synuclein, has become one of the most attractive targets for developing new drugs with the potential to slow down or arrest the progression of Parkinson's disease

20 Dec 2018

$Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction$

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

Researchers at the University of Arizona have discovered that metformin, a drug commonly used to treat type 2 diabetes, might also be used to treat heart failure with preserved ejection fraction, a condition that is predicted to affect over 8% of people ages 65 or older by the year 2020.

19 Dec 2018

Personalization techniques give a new lease of life to anticancer vaccines

Anticancer vaccines have gained a new lease of life with techniques to personalise them to individual patients.

19 Dec 2018

Research explores effects of cannabis use on males’ reproductive health

As legal access to marijuana continues expanding across the U.S., more scientists are studying the effects of its active ingredient, tetrahydrocannabinol (THC), in teens, adults and pregnant women.

19 Dec 2018

Hepatitis C drug can eliminate chikungunya, yellow fever virus

A study performed at the University of São Paulo's Biomedical Science Institute (ICB-USP) in Brazil shows that sofosbuvir, a drug used to treat chronic hepatitis C, is capable of eliminating chikungunya virus and yellow fever virus.

19 Dec 2018

Potential combination therapy against rare disease of the bone marrow could improve treatment

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. Its low incidence rate is one of the reasons why effective therapies are still lacking.

19 Dec 2018

Increasing prevalence of antibiotic resistance in the U.S. linked with occasional use

The increasing prevalence of antibiotic resistance in the U.S. appears more closely linked with their occasional use by many people than by their repeated use among smaller numbers of people, according to a large new study from Harvard T.H. Chan School of Public Health.

18 Dec 2018

Study reveals mechanism behind failed remyelination in MS

Researchers have discovered that in adult stem cells, the activation of a specific transcription factor induces pathological quiescence and that this is deactivated in MS.

18 Dec 2018

Pharmaceutical News

New review focuses on the structure-activity relationships of flavonoids

Breast cancer drugs could tackle lung cancers resistant to targeted therapies

Study: Reactivation of HIV-infected cells depends on its size and cell cycle

Lupin partners with Abbvie to develop and commercialize new targeted oncology treatments

Statins reduce the formation of brown adipose tissue

New treatment for adults with rare, life-threatening blood disease receives FDA approval

Study shows high rates of antibiotic overuse in patients undergoing common urological procedures

FDA approves new treatment for rare disease of the bone marrow and blood

Combination of statins and Mediterranean diet more effective in reducing cardiovascular mortality risk

Bacterial resistance to last-resort antibiotic is spreading at alarming rate in Vietnam

Scientists develop novel eye drop that reduces sight-threatening scarring to the eye surface

Study provides information about chemotherapeutic drugs binding to plasma proteins

Experts in Parkinson's research propose roadmap for drug trials targeting alpha-synuclein

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

Personalization techniques give a new lease of life to anticancer vaccines

Research explores effects of cannabis use on males’ reproductive health

Hepatitis C drug can eliminate chikungunya, yellow fever virus

Potential combination therapy against rare disease of the bone marrow could improve treatment

Increasing prevalence of antibiotic resistance in the U.S. linked with occasional use

Study reveals mechanism behind failed remyelination in MS

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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