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Mount Sinai joins with Paradigm and ReqMed to repurpose drug for treatment of MPS

The Icahn School of Medicine at Mount Sinai has entered into two exclusive licenses to develop the drug pentosan polysulfate sodium for and ReqMed Company, Ltd. of Japan.

21 Jan 2019

County by county, researchers link opioid deaths to drugmakers’ marketing

Researchers sketched a vivid line Friday linking the dollars spent by drugmakers to woo doctors around the country to a vast opioid epidemic that has led to tens of thousands of deaths.

18 Jan 2019

Microrobots could one day deliver drugs inside the body

Researchers have developed highly advanced miniaturized smart robots designed to change their shape as they encounter different bodily fluids.

18 Jan 2019

Computerized method helps better protect pharma patents

Routes to making life-saving medications and other pharmaceutical compounds are among the most carefully protected trade secrets in global industry.

18 Jan 2019

Ural Federal University scientists synthesize a group of multi-purpose fluorophores

A group of scientists from Russia's Ural Federal University, headed by Professor Grigory Zyryanov, synthesized a group of multi-purpose fluorophores.

18 Jan 2019

Podcast: KHN’s ‘What the Health?’ Drug prices are rising again. Is someone going to do something about it?

Many drugmakers have announced price increases with the start of the new year. The new Congress wants to do something about that. And even though both Republicans and Democrats want to address the politically potent issue of drug prices, it is unclear what they might be able to agree on.

17 Jan 2019

Improvements in pharmacological study to fight cognitive impairment in schizophrenia

A study by the UPV/EHU has assessed the effectiveness of various drugs, which are used to delay cognitive deterioration in patients with Alzheimer's, in improving cognitive impairment displayed by patients with schizophrenia.

17 Jan 2019

QIAGEN receives first companion diagnostic approval in Japan

QIAGEN N.V. today announced that the Japanese Pharmaceuticals and Medical Device Agency has approved the therascreen EGFR RGQ PCR Kit to allow its use as a companion diagnostic with Pfizer's VIZIMPRO (dacomitinib) for EGFR gene mutation-positive, inoperable or recurrent non-small cell lung cancer.

17 Jan 2019

Study looks at trends over time in oral antibiotic prescribing by dermatologists

This study looked at trends over time in oral antibiotic prescribing by dermatologists using commercial insurance claims data for almost 986,000 courses of oral antibiotics prescribed by nearly 12,000 dermatologists.

17 Jan 2019

Study determines impact of antibiotic perturbation of the gut microbiome on skeletal health

Microbes are often seen as pathogens that cause disease and antibiotics have been used successfully to combat these foreign invaders. In reality, the picture is more complex.

17 Jan 2019

Opioid drugs often overprescribed to children for pain relief, say CHOP surgeons

Opioid drugs prescribed to children for pain relief after a typical pediatric orthopaedic procedure may be significantly overprescribed, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP).

17 Jan 2019

New study finds only 13% of outpatient antibiotic prescriptions to be appropriate

A new Northwestern Medicine study found only 13 percent of outpatient antibiotic prescriptions were appropriate, with 36 percent considered potentially appropriate.

17 Jan 2019

Mutant mice administered with cocaine failed to exhibit hyperactivity, shows study

Cocaine is a highly addictive psychostimulant that induces complex molecular, cellular and behavioral responses. Despite various approaches and years of pre-clinical studies, effective, mechanism-based therapies to assist with cocaine misuse and dependence are still sorely lacking.

16 Jan 2019

FDA approves generic drug for treating focal seizures

The U.S. Food and Drug Administration approved the first generic version of Sabril (vigabatrin) 500 mg tablets for treating complex partial seizures, also called focal seizures, as an adjunctive therapy (given with another primary treatment) in patients 10 years and older who have responded inadequately to several alternative (refractory) treatments.

16 Jan 2019

QPS launches new brand identity to support continued global expansion

The year 2019 marks 24 years of growth for QPS, LLC, a leading global CRO focused on bioanalytics and clinical trials that accelerate pharmaceutical breakthroughs.

16 Jan 2019

Cobra Biologics announces appointment of Dr Darrell Sleep as Director of Innovation

Cobra Biologics, an international CDMO for biologics and pharmaceuticals, today announced the appointment of Dr Darrell Sleep as Director of Innovation.

From Charles River 16 Jan 2019

Hypertension drug may improve effectiveness of ovarian cancer treatment

A new study from a Massachusetts General Hospital research team has found that the hypertension drug losartan, which targets the angiotensin signaling pathway, may improve the effectiveness of chemotherapy agents used to treat ovarian cancer

16 Jan 2019

Most substance use disorder treatment facilities do not offer medication treatment

Despite the mounting death toll of America's opioid crisis, only a minority of facilities that treat substance use disorders offer patients buprenorphine, naltrexone or methadone--the three FDA-approved medications for the long-term management of opioid use disorder, according to a new study from researchers at the Johns Hopkins Bloomberg School of Public Health.

16 Jan 2019

University of Nebraska to develop new drugs that prevent and counteract effects of radiation exposure

The U.S. Department of Defense has turned to the University of Nebraska to jumpstart the development of drug therapies to protect military service members from the effects of radiation exposure.

16 Jan 2019

FDA-approved drug hampers cancer metastasis in animal model, shows study

For cancer to spread, it needs a hospitable environment in distant organs. This fertile "soil" can provide a home to circulating malignant cells.

16 Jan 2019

Pharmaceutical News

Mount Sinai joins with Paradigm and ReqMed to repurpose drug for treatment of MPS

County by county, researchers link opioid deaths to drugmakers’ marketing

Microrobots could one day deliver drugs inside the body

Computerized method helps better protect pharma patents

Ural Federal University scientists synthesize a group of multi-purpose fluorophores

Podcast: KHN’s ‘What the Health?’ Drug prices are rising again. Is someone going to do something about it?

Improvements in pharmacological study to fight cognitive impairment in schizophrenia

QIAGEN receives first companion diagnostic approval in Japan

Study looks at trends over time in oral antibiotic prescribing by dermatologists

Study determines impact of antibiotic perturbation of the gut microbiome on skeletal health

Opioid drugs often overprescribed to children for pain relief, say CHOP surgeons

New study finds only 13% of outpatient antibiotic prescriptions to be appropriate

Mutant mice administered with cocaine failed to exhibit hyperactivity, shows study

FDA approves generic drug for treating focal seizures

QPS launches new brand identity to support continued global expansion

Cobra Biologics announces appointment of Dr Darrell Sleep as Director of Innovation

Hypertension drug may improve effectiveness of ovarian cancer treatment

Most substance use disorder treatment facilities do not offer medication treatment

University of Nebraska to develop new drugs that prevent and counteract effects of radiation exposure

FDA-approved drug hampers cancer metastasis in animal model, shows study

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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