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FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

The U.S. Food and Drug Administration today approved Poteligeo (mogamulizumab-kpkc) injection for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sézary syndrome after at least one prior systemic therapy.

8 Aug 2018

Mandatory vaccinations for children stopped in Italy

The Italian government has removed the necessity for all children to be vaccinated against 10 important infectious diseases before they can join school or day care. This has shocked and angered the medical and scientific community.

7 Aug 2018

Taking cholesterol-busting pills can effectively treat brutal PAP

Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis, and they show taking cholesterol-busting pills called statins can effectively treat the disease.

7 Aug 2018

Extended-release naltrexone appears to help HIV-positive patients reduce heavy drinking

Extended-release naltrexone -- an injection that decreases heavy drinking in the general population when taken in conjunction with counseling -- appears to help HIV-positive individuals reduce their number of heavy drinking days too, say Yale researchers.

7 Aug 2018

Scientists create new tool to precisely control 3D architecture of linkages in drugs

When it comes to certain molecules, shape makes all the difference. The shape of limonene, for instance, a compound produced by citrus fruits, determines whether it tastes like orange juice or turpentine.

7 Aug 2018

Injecting vasoactive intestinal peptide into the eye enhances corneal graft survival

A new study in the American Journal of Pathology reports for the first time that injection of neuropeptide vasoactive intestinal peptide directly into the eye of mice enhanced corneal graft survival.

7 Aug 2018

Doxorubicin drug causes heart toxicity by disrupting the immune system

Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart failure.

7 Aug 2018

Medicaid expansion increases access to diabetes treatment

Prescriptions for diabetes medications increased in the first two years after states expanded eligibility for Medicaid as part of the Affordable Care Act, compared to states that didn't expand Medicaid.

7 Aug 2018

WVU researchers examine safety of Suboxone use in opioid-dependent pregnant women

Medications that physicians have traditionally prescribed to treat opioid use disorders-such as methadone and Subutex-can be misused by taking them in larger amounts than prescribed or by injecting them.

7 Aug 2018

FDA issues scientific recommendations to encourage development of novel drugs for treatment of OUD

The U.S. Food and Drug Administration today issued new scientific recommendations aimed at encouraging more widespread innovation and development of novel medication-assisted treatment drugs for the treatment of opioid use disorder.

7 Aug 2018

Medicaid expansion making diabetes meds more accessible to poor, study shows

Low-income people with diabetes are better able to afford their medications and manage their disease in states that expanded Medicaid under the Affordable Care Act, a new study suggests.

6 Aug 2018

EMA grants orphan designation to selumetinib for treatment of neurofibromatosis type 1

AstraZeneca and Merck, known as MSD outside the U.S. and Canada, today announced that the European Medicines Agency (EMA) has granted orphan designation to selumetinib, a MEK 1/2 inhibitor, for the treatment of neurofibromatosis type 1 (NF1).

3 Aug 2018

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Regenacy Pharmaceuticals, LLC, a clinical-stage biopharmaceutical company developing breakthrough treatments for diabetic and other peripheral neuropathies, today announced a collaboration with the Charcot-Marie-Tooth Association, a registered non-profit organization serving the hereditary neuropathy patient community, to validate the role of HDAC6 in multiple forms of Charcot-Marie-Tooth disease and evaluate the efficacy of ricolinostat, a selective HDAC6 inhibitor, in animal models.

2 Aug 2018

Otsuka’s JINARC approved for treatment of patients with CKD stage 4 ADPKD

Otsuka Pharmaceutical Europe Ltd. today announced that the European Commission has approved an extension of indication for JINARC to include adult patients with CKD stage 4 Autosomal Dominant Polycystic Kidney Disease

2 Aug 2018

Scientists solve 60-year-old mystery of how thalidomide caused birth defects

More than 60 years after the drug thalidomide caused birth defects in thousands of children whose mothers took the drug while pregnant, scientists at Dana-Farber Cancer Institute have solved a mystery that has lingered ever since the dangers of the drug first became apparent: how did the drug produce such severe fetal harm?

2 Aug 2018

How rival opioid makers sought to cash in on alarm over oxycontin’s dangers

As Purdue Pharma faced mounting criticism over deaths linked to OxyContin, rival drugmakers saw a chance to boost sales by stepping up marketing of similarly dangerous painkillers, such as fentanyl, morphine and methadone, Purdue internal documents reveal.

2 Aug 2018

Folic acid may prevent language delays in children of mothers with epilepsy

Women who take epilepsy drugs while they are pregnant may have a lower risk of having a child with delays in language skills if they take folic acid supplements before and early in pregnancy, according to a study published in the August 1, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

2 Aug 2018

Alzheimer's drug may prevent disease progression if used before symptoms appear

About 50 percent of people who reach the age of 85 will develop Alzheimer's disease. Most will die within about five years of exhibiting the hallmark symptoms of the disease - severe memory loss and a precipitous decline in cognitive function.

2 Aug 2018

Ketamine may be potential therapeutic option for adolescents with treatment-resistant depression

A new study has shown a significant average decrease in the Children's Depression Rating Scale among adolescents with treatment-resistant depression who were treated with intravenous ketamine.

2 Aug 2018

Peer comparison letters lead to persistent decrease in antipsychotic prescribing

A study led by Columbia University's Mailman School of Public Health has found that letters targeting high prescribers of Seroquel, an antipsychotic with potentially harmful side effects in the elderly, significantly reduced the number of prescriptions for patients in Medicare.

2 Aug 2018

Pharmaceutical News

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

Mandatory vaccinations for children stopped in Italy

Taking cholesterol-busting pills can effectively treat brutal PAP

Extended-release naltrexone appears to help HIV-positive patients reduce heavy drinking

Scientists create new tool to precisely control 3D architecture of linkages in drugs

Injecting vasoactive intestinal peptide into the eye enhances corneal graft survival

Doxorubicin drug causes heart toxicity by disrupting the immune system

Medicaid expansion increases access to diabetes treatment

WVU researchers examine safety of Suboxone use in opioid-dependent pregnant women

FDA issues scientific recommendations to encourage development of novel drugs for treatment of OUD

Medicaid expansion making diabetes meds more accessible to poor, study shows

EMA grants orphan designation to selumetinib for treatment of neurofibromatosis type 1

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Otsuka’s JINARC approved for treatment of patients with CKD stage 4 ADPKD

Scientists solve 60-year-old mystery of how thalidomide caused birth defects

How rival opioid makers sought to cash in on alarm over oxycontin’s dangers

Folic acid may prevent language delays in children of mothers with epilepsy

Alzheimer's drug may prevent disease progression if used before symptoms appear

Ketamine may be potential therapeutic option for adolescents with treatment-resistant depression

Peer comparison letters lead to persistent decrease in antipsychotic prescribing

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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