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RBC-hitchhiking method increases concentration of drugs ferried to selected organs

A new drug-delivery technology which uses red blood cells to shuttle nano-scale drug carriers, called RBC-hitchhiking, has been found in animal models to dramatically increase the concentration of drugs ferried precisely to selected organs, according to a study published in Nature Communications this month by researchers from the Perelman School of Medicine at the University of Pennsylvania.

2 Aug 2018

New treatment may be on the horizon for Parkinson's disease

More of us are susceptible to Parkinson's as we age, as evidenced by actor Alan Alda's recent diagnosis. A new treatment may be on the horizon.

2 Aug 2018

Exenatide treatment improves depression symptoms in PD patients

Non-motor symptoms of Parkinson's disease, such as depression, apathy, cognitive impairment, sleep disorders, and sensory symptoms, can have a greater impact on health-related quality of life than motor deficits.

1 Aug 2018

BIDMC researchers identify risk factors that increase risk of prolonged opioid use

Current research demonstrates that patients' exposure to opioids following medical care has contributed to the nationwide addiction epidemic.

1 Aug 2018

CFDA accepts Ascletis’ NDA for first all-oral HCV treatment

Ascletis announced today it has received the acceptance letter from the China Food and Drug Administration for Ravidasvir new drug application.

1 Aug 2018

To tame prescription prices, HHS dips a toe into drug importation stream

It came as something of a surprise when Health and Human Services Secretary Alex Azar announced that the administration was exploring the importation of prescription drugs to fight high domestic prices.

1 Aug 2018

New drug cocktails make targeted cancer therapies more efficient with less side effects

Mount Sinai researchers have discovered that certain drug cocktails help targeted therapies attack cancer more efficiently while lessening common side effects, according to a study published today in Cancer Research.

1 Aug 2018

Patients with chronic pain feel caught in an opioid-prescribing debate

It started with a rolled ankle during a routine Army training exercise. Shannon Hubbard never imagined it was the prologue to one of the most debilitating pain conditions known to exist, called complex regional pain syndrome.

1 Aug 2018

New AI approach can teach itself to design new drug molecules from scratch

An artificial-intelligence approach created at the University of North Carolina at Chapel Hill Eshelman School of Pharmacy can teach itself to design new drug molecules from scratch and has the potential to dramatically accelerate the design of new drug candidates.

1 Aug 2018

Researchers engineer three cell lines to produce nonproprietary versions of NISTmAb

When the National Institute of Standards and Technology issued the world's first standardized monoclonal antibody in July 2016, the exhaustively analyzed protein known as NISTmAb was intended as a valuable tool for biopharmaceutical companies.

1 Aug 2018

New guidelines provide framework for responding to drug shortages and to improve patient care

Healthcare teams in patient care settings can develop policies and procedures to minimize the impact of drug shortages by incorporating new guidelines published today by ASHP (American Society of Health-System Pharmacists).

31 Jul 2018

European Commission approves Pfizer’s first oncology biosimilar

Pfizer Inc. today announced the European Commission has approved TRAZIMERA, a biosimilar to Herceptin (trastuzumab), for the treatment of human epidermal growth factor overexpressing breast cancer and HER2 overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.

31 Jul 2018

FDA approves first ever non-surgical treatment for rare neuroendocrine cancers

The U.S. Food and Drug Administration has approved the first ever non-surgical treatment for the rare neuroendocrine cancers pheochromocytoma and paraganglioma.

31 Jul 2018

New method to evaluate drug benefits may reduce health care costs

With the cost of drugs a critical issue in health care, health insurance companies and government payers need to understand how new and existing drugs compare in terms of benefits and risks.

31 Jul 2018

Researchers investigate potential of injectable trace minerals to keep dairy cows healthier

When dairy cattle consume aflatoxin-contaminated feed, they are lethargic, their appetite wanes, they produce less milk, and their immune system goes awry.

31 Jul 2018

FDA approves first therapy for patients with rare tumors of the adrenal gland

The U.S. Food and Drug Administration today approved Azedra (iobenguane I 131) injection for intravenous use for the treatment of adults and adolescents age 12 and older with rare tumors of the adrenal gland (pheochromocytoma or paraganglioma) that cannot be surgically removed (unresectable), have spread beyond the original tumor site and require systemic anticancer therapy.

31 Jul 2018

Ivosidenib receives FDA approval to treat acute myeloid leukemia patients with IDH1 mutation

Clinical trials at University of Colorado Cancer Center and elsewhere now result in the drug ivosidenib earning approval from the U.S. Food and Drug Administration for the treatment of adult patients with relapsed or refractory acute myeloid leukemia with a susceptible isocitrate dehydrogenase-1 mutation.

30 Jul 2018

New findings suggest opportunity to focus on safe opioid use and disposal among older adults

Nearly a third of older adults have received a prescription for an opioid pain medicine in the past two years, but many of them didn't get enough counseling about the risks that come with the potent painkillers, how to reduce their use, when to switch to a non-opioid option, or what to do with leftover pills, a new poll finds.

30 Jul 2018

New study provides insight into how stimulant treatments for ADHD work

Stimulant medications are an effective treatment for Attention-Deficit/Hyperactivity Disorder. In the classroom, parents and teachers say that medications like methylphenidate can reduce symptoms and improve behavior.

28 Jul 2018

Drug that treats diabetes found to exert powerful check on macrophages in controlling inflammation

When tissue is damaged, one of the body's first inflammatory immune-system responders are macrophages, cells which are commonly thought of as "construction workers" that clear away damaged tissue debris and initiate repair.

28 Jul 2018

Pharmaceutical News

RBC-hitchhiking method increases concentration of drugs ferried to selected organs

New treatment may be on the horizon for Parkinson's disease

Exenatide treatment improves depression symptoms in PD patients

BIDMC researchers identify risk factors that increase risk of prolonged opioid use

CFDA accepts Ascletis’ NDA for first all-oral HCV treatment

To tame prescription prices, HHS dips a toe into drug importation stream

New drug cocktails make targeted cancer therapies more efficient with less side effects

Patients with chronic pain feel caught in an opioid-prescribing debate

New AI approach can teach itself to design new drug molecules from scratch

Researchers engineer three cell lines to produce nonproprietary versions of NISTmAb

New guidelines provide framework for responding to drug shortages and to improve patient care

European Commission approves Pfizer’s first oncology biosimilar

FDA approves first ever non-surgical treatment for rare neuroendocrine cancers

New method to evaluate drug benefits may reduce health care costs

Researchers investigate potential of injectable trace minerals to keep dairy cows healthier

FDA approves first therapy for patients with rare tumors of the adrenal gland

Ivosidenib receives FDA approval to treat acute myeloid leukemia patients with IDH1 mutation

New findings suggest opportunity to focus on safe opioid use and disposal among older adults

New study provides insight into how stimulant treatments for ADHD work

Drug that treats diabetes found to exert powerful check on macrophages in controlling inflammation

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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