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Local anesthetic drug not linked to reduction in opioid use, complications after knee surgery

Contrary to what some studies may suggest, the local anesthetic drug, liposomal bupivacaine, did not reduce in-hospital opioid prescriptions or opioid-related complications in patients who received the drug during total knee replacement surgery as part of a multimodal approach to manage postsurgical pain, finds a new study published in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists.

22 May 2018

Middlemen who save $$ on medicines — but maybe not for you

Guess who's back grabbing headlines? Pharmacy benefit managers — those companies that serve as middlemen in the prescription drug pipeline.

21 May 2018

In-hospital opioid prescribing may increase post-discharge opioid use, shows study

Patients who receive an opioid for most of their hospital stay and patients who are still taking an opioid within 12 hours of being discharged from the hospital appear more likely to fill a prescription for opioids within 90 days of leaving the hospital, according to new research presented at the ATS 2018 International Conference.

21 May 2018

New case report reveals negative clinical impact of using biotin supplement

A new case report in the Journal of the Endocrine Society documents how a patient's use of a common biotin supplement, also known as vitamin B7, caused her to have clinically misleading test results, which prompted numerous consultations and unnecessary radiographic and laboratory testing.

21 May 2018

Biomarker blood test does not appear to curb antibiotic overuse, shows new study

Overall antibiotic use was not curbed by giving physicians the results of biomarker tests in patients with suspected lower respiratory tract infections, according to findings from the Procalcitonin Antibiotic Consensus Trial.

21 May 2018

Study: Psoriasis patients taking Humira show no change in aortic inflammation

An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation – a key marker of future risk of major cardiovascular events – unlike other antibodies that target different aspects of the immune system.

18 May 2018

Vermont legislators pass a drug importation law. So what?

This week, Vermont passed a first-in-the-nation law that would facilitate the state's importation of prescription drugs wholesale from Canada. It represents the state's effort to tackle head-on the issue of constantly climbing drug prices.

18 May 2018

HIV patients on single-tablet regimen show better outcomes than those taking multiple pills

HIV patients on a single-tablet daily regimen had better treatment retention and viral suppression than patients taking multiple pills, in a study by a Michael E. DeBakey Veterans Affairs Medical Center researcher and his colleagues.

18 May 2018

FDA OKs first non-opioid drug for adults with opioid withdrawal symptoms

The United States Food and Drugs Administration (FDA), in a statement this week, approved a new drug Lucemyra (lofexidine hydrochloride) for the treatment and alleviation of opioid symptom withdrawal symptoms in adults in whom the drugs have been withdrawn abruptly.

17 May 2018

Old drug offers new hope for treatment of MND

An international study led by biochemists at the University of Liverpool has shown that the drug-molecule ebselen can correct many of the toxic characteristics of a protein that causes some cases of hereditary motor neurone disease (MND).

17 May 2018

Drug combination may prevent secondary stroke in certain patients, study shows

Results from an international clinical trial of more than 4880 participants, published in the New England Journal of Medicine, show that combining clopidogrel and aspirin following a small stroke or experiencing minor stroke symptoms decreases risk of a new stroke, heart attack or other ischemic event within 90 days.

17 May 2018

Doctors publish comprehensive proposal to ensure universal access to safe, affordable medications

The skyrocketing cost of prescription drugs is one of the biggest concerns for American voters. However, in his proposal last Friday, President Donald Trump failed to offer any new policies that would expand access, reduce costs, or increase the safety and efficacy of prescriptions.

17 May 2018

Expectant mothers may use RA drugs without increased health risks to unborn babies

A new study led by a team at the Research Institute of the MUHC in Montreal has revealed that pregnant women with rheumatoid arthritis may be able to use certain RA drugs without possible increased health risks to their unborn babies.

17 May 2018

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

The U.S. Food and Drug Administration today approved Lucemyra (lofexidine hydrochloride) for the mitigation of withdrawal symptoms to facilitate abrupt discontinuation of opioids in adults.

17 May 2018

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

In a recent study published in the Journal of Clinical Investigation, Mayo Clinic researchers identified that an FDA drug approved for myelodysplastic syndrome may be useful to treat triple-negative breast cancer, which is one of the most aggressive and lethal types of breast cancer.

16 May 2018

Clinical study shows promising results of Nexodyn AcidOxidizing Solution in healing chronic wounds

APR Applied Pharma Research sa, the Swiss independent developer of science driven and patent protected healthcare products, today announces the publication in "Advances in skin & wound care" of the results of a clinical pilot study on the efficacy and tolerability of Nexodyn AcidOxidizing Solution, a sprayable Active Cleanser with ancillary antimicrobial activity developed for acute and chronic wound management.

16 May 2018

Emulate partners with AstraZeneca to accelerate development of Organs-on-Chips technology

Emulate, Inc. has formed a collaborative partnership with AstraZeneca's Innovative Medicines and Early Development Biotech Unit to embed its Organs-on-Chips technology within the laboratories of the IMED Drug Safety organization.

16 May 2018

FDA clears Turnstone Biologics' IND for immunotherapy targeting HPV positive solid tumors

Turnstone Biologics today announced it has received U.S. Food and Drug Administration clearance of its Investigational New Drug Application for MG1-HPV for the treatment of patients with human papillomavirus positive solid tumors.

16 May 2018

Taking clot-preventing drug with aspirin may lower risk of major stroke, finds study

The research was part of the Platelet-Oriented Inhibition in New TIA and minor ischemic stroke trial -- a randomized, double-blind, placebo-controlled trial conducted between May 2010 and December 2017.

16 May 2018

Reversing an overdose isn’t complicated, but getting the antidote can be

A few months ago, Kourtnaye Sturgeon helped save someone’s life. She was driving in downtown Indianapolis when she saw people gathered around a car on the side of the road. Sturgeon pulled over, and a man told her there was nothing she could do: Two men had overdosed on opioids and appeared to be dead.

16 May 2018

Pharmaceutical News

Local anesthetic drug not linked to reduction in opioid use, complications after knee surgery

Middlemen who save $$ on medicines — but maybe not for you

In-hospital opioid prescribing may increase post-discharge opioid use, shows study

New case report reveals negative clinical impact of using biotin supplement

Biomarker blood test does not appear to curb antibiotic overuse, shows new study

Study: Psoriasis patients taking Humira show no change in aortic inflammation

Vermont legislators pass a drug importation law. So what?

HIV patients on single-tablet regimen show better outcomes than those taking multiple pills

FDA OKs first non-opioid drug for adults with opioid withdrawal symptoms

Old drug offers new hope for treatment of MND

Drug combination may prevent secondary stroke in certain patients, study shows

Doctors publish comprehensive proposal to ensure universal access to safe, affordable medications

Expectant mothers may use RA drugs without increased health risks to unborn babies

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

Clinical study shows promising results of Nexodyn AcidOxidizing Solution in healing chronic wounds

Emulate partners with AstraZeneca to accelerate development of Organs-on-Chips technology

FDA clears Turnstone Biologics' IND for immunotherapy targeting HPV positive solid tumors

Taking clot-preventing drug with aspirin may lower risk of major stroke, finds study

Reversing an overdose isn’t complicated, but getting the antidote can be

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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