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New research design offers way to assess safety of approved drugs

As the pace of drug approvals accelerates and the U.S. Food and Drug Administration faces potential budget cuts, a new research design from Perelman School of Medicine scientists offers a new way to successfully assess safety of newly approved drugs, as well as drugs that have been on the market for a long time and have had a marked rise in their use.

9 Jun 2017

Scientists find way to recover protein structure after chemical denaturation

Scientists from ITMO University in Saint Petersburg and Hebrew University in Jerusalem have found a way to recover a protein structure after its chemical denaturation.

9 Jun 2017

Cesarean patients prescribed more opioid pain medications than needed, study shows

Most women who undergo a cesarean childbirth are prescribed more opioid (narcotic) pain medications than needed upon release from the hospital, a Vanderbilt University Medical Center study shows.

9 Jun 2017

UNC researchers identify how class of antiviral drugs interacts with HCV

Globally, an estimated 71 million people are living with chronic hepatitis C virus (HCV). Over decades of infection, chronic HCV infection results in progressive damage to the liver and an increased risk for end stage liver disease and liver cancer, making the virus the leading cause of liver-related deaths in the United States today.

9 Jun 2017

Novartis announces data revealing efficacy of new monoclonal antibody therapy in preventing migraine

Novartis today announced that it will present 19 scientific abstracts at the 59th Annual Scientific Meeting of the American Headache Society.

8 Jun 2017

Women with diabetes who use low-dose aspirin have reduced breast cancer risk

A new study of nearly 149,000 women with diabetes over 14 years showed an overall 18% reduced breast cancer risk for women who used low-dose aspirin compared to those who did not.

8 Jun 2017

Former pharma reps’ new mission: To school docs on high drug costs

As a drug salesman, Mike Courtney worked hard to make health care expensive. He wined and dined doctors, golfed with them and bought lunch for their entire staffs — all to promote pills often costing thousands of dollars a year.

8 Jun 2017

Women pay 40% more than men for common hair loss medication, study finds

Women pay an average of 40 percent more than men for minoxidil foams – a hair loss remedy most commonly known as Rogaine – according to a new analysis from researchers at the Perelman School of Medicine at the University of Pennsylvania.

8 Jun 2017

New prediction tools could identify patients at risk of inappropriate prescription opioid use

New prediction tools to help health-care providers identify patients at risk of inappropriate prescription opioid use, while allowing safe administration of legitimate pain management to those not at high-risk, are being developed by University of Arizona College of Pharmacy researcher Jenny Lo-Ciganic, PhD.

8 Jun 2017

Prebiotics may be new weapon in the fight against childhood obesity

There may soon be a new tool in the fight against childhood obesity. Prebiotics reduce body fat in children who are overweight or obese by altering their gut microbiota, according to new research published in Gastroenterology, the official journal of the American Gastroenterological Association.

7 Jun 2017

Daylight on diabetes drugs: Nevada bill would track insulin makers’ profits

Patients notched a rare win over the pharmaceutical industry Monday when the Nevada Legislature revived a bill requiring insulin makers to disclose the profits they make on the life-sustaining drug. In a handful of other states, bills addressing drug prices have stalled.

7 Jun 2017

New review explores effect of HPV vaccination on cervical cancer screening

A new review looks at cervical cancer screening in the era of HPV vaccination. The review notes that trials have demonstrated the efficacy and safety of vaccines against HPV infection, but the complete effect of HPV vaccination as a cancer prevention strategy may not be fully evident for decades, given the slow progression from HPV infection to the development of cervical cancer.

7 Jun 2017

Use of cardiovascular medications linked to fall risk in older adults

A new analysis suggests that among older adults who take cardiovascular medications, those using non-selective beta-blockers may be at an increased of falling compared with those using selective beta-blockers.

7 Jun 2017

Two-pronged algorithm may prove to be accurate tool for predicting response to checkpoint inhibitors

The class of immunotherapies known as checkpoint inhibitors have proven to be a highly effective and advantageous treatment option for many cancer patients, but they don't work well for everyone, and oncologists have no reliable way to determine in advance which patients are likely to respond to these drugs.

7 Jun 2017