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Recovery on the reservation: Montana sisters help peers stop using drugs

There’s a narrative about the meth epidemic in Montana that says the state tackled the problem in the 2000s yet it’s back with a vengeance because of super labs and drug cartels in Mexico. Within the Fort Belknap Indian Community, though, it never really went away.

6 Jun 2017

Aspirin may provide little or no benefit for certain patients with narrowed, hardened arteries

For decades, aspirin has been widely used to reduce the risk of cardiovascular problems. Now, a team led by a University of Florida Health researcher has found that aspirin may provide little or no benefit for certain patients who have plaque buildup in their arteries.

6 Jun 2017

Diabetes medication can protect against cardiac stiffening in obese female mice

Overconsumption of a Western diet high in fats and refined sugars has contributed to a global increase in obesity and Type 2 diabetes.

6 Jun 2017

Opioid use gradually increases few years after bariatric surgery, study shows

While the proportion of adults with severe obesity using prescription opioids initially declines in the months after bariatric surgery, it increases within a matter of years, eventually surpassing pre-surgery rates of patients using the potentially addictive pain medications, according to new research from a National Institutes of Health -funded multicenter study led by the University of Pittsburgh Graduate School of Public Health.

6 Jun 2017

Study: 1 in 6 patients on new blood-thinning medications may not be receiving recommended dose

Almost 1 in 6 of the millions of Americans on the new blood-thinning medications for atrial fibrillation, a common heart condition characterized by an irregular and often rapid heart rate, may not be receiving the recommended dose, new Mayo Clinic research finds.

5 Jun 2017

Novartis, Bristol-Myers Squibb collaborate to examine combination therapies for metastatic colorectal cancer

Novartis today announced it has entered into a clinical research collaboration in which Bristol-Myers Squibb will investigate the safety, tolerability, and efficacy of Mekinist (trametinib) in combination with Opdivo (nivolumab) and Opdivo + Yervoy (ipilimumab) regimen as a potential treatment option for metastatic colorectal cancer in patients with microsatellite stable tumors where the tumors are proficient in mismatch repair (MSS mCRC pMMR).

5 Jun 2017

Study finds increasing susceptibility of Staphylococcus aureus in U.S. hospital patients

Findings from a study that looked at susceptibility trends of Staphylococcus aureus in U.S. hospital patients showed that key antibiotics used to treat the bacteria became more active over the course of the study, a rare occurrence.

5 Jun 2017

Improved communication could help reduce unnecessary use of antibiotics for childhood illnesses

To help reduce unnecessary use of antibiotics for common childhood illnesses, parents would benefit from fuller communication from their health care providers, suggests new research published in the National Communication Association's Journal of Applied Communication Research.

5 Jun 2017

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

A new study has shown that AstraZeneca's Lynparza (olaparib) can significantly slow the progress of breast cancer that is caused partially due to mutations of the culprit gene called BRCA. BRCA gene mutations are responsible for around 3% of all breast cancers. These cases of the disease that have a basis in the gene are notoriously difficult to treat and women who are tested positive for this gene may even opt for removal of their breasts before even the cancer strikes. Noted actress Angelina Jolie went for a similar prophylactic mastectomy.

5 Jun 2017

$Study finds higher risk of fractures among older, long-term bisphosphonate users$

Study finds higher risk of fractures among older, long-term bisphosphonate users

Osteoporosis is a disease that causes thinning of the bones, loss of bone density, and increasingly fragile bones. This puts people at higher risk for bone fractures. Risk for the disease increases as we age. In fact, 50% of women over the age of 50 will experience a bone facture due to osteoporosis.

2 Jun 2017

UTI treatment with antibiotics for older adults may be more harmful than previously thought

In a new research paper published in the Journal of the American Geriatrics Society, Thomas E. Finucane, MD, of the Johns Hopkins Geriatrics Center at Johns Hopkins in Baltimore, suggests that prescribing antibiotics for urinary tract infections (or "UTIs") may often be avoided among older adults.

2 Jun 2017

Patients nearing end of life may not feel abandoned after discontinuation of cholesterol medications

New research suggests patients nearing the end of their lives because of a "life-limiting illness" such as cancer or heart disease may not feel medically abandoned if their doctor wants to take them off the statins that control their cholesterol.

2 Jun 2017

Assessing safety and toxicity of bioactives could be key to establishing tolerable upper intake levels

The good news is out that wine and dark chocolate may be good for your health. That's because of substances known as bioactives that are contained in those foods.

2 Jun 2017

UCSB biologists develop new antimicrobial susceptibility test to transform the way antibiotics are tested

When a patient is prescribed the wrong antibiotic to treat a bacterial infection, it's not necessarily the physician who is at fault. The current antibiotic assay -- standardized in 1961 by the World Health Organization and used worldwide -- is potentially flawed.

2 Jun 2017

Antidepressant use during pregnancy not linked to newborn problems at 2-4 weeks after birth

Babies exposed to an antidepressant or a mood disorder during fetal life did not have any more signs of irritability, difficulty feeding, sleep disturbances and respiratory problems two to four weeks after birth than babies who were not exposed.

1 Jun 2017

Study reveals key role of gut microbiota in treatment with classic diabetes medication

A clearer picture of how the classic diabetes medication metformin works has emerged. A recent study at Sahlgrenska Academy and University of Girona indicates that the clinical effect - control of blood glucose - is achieved through modulation of the gut microbiota.

1 Jun 2017

Study finds decline in rates of HPV-related precancerous cervical lesions among women in Connecticut

The vaccine for the Human Papillomavirus is proving to have significant population-level effects in Connecticut, with rates of precancerous lesions caused by HPV down drastically among young women, a new Yale School of Public Health study finds.

31 May 2017

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

Combining the kinase inhibitor ibrutinib with an investigational personalized cellular therapy known as CTL119 can lead to complete remission in patients with high-risk chronic lymphocytic leukemia (CLL), according to new research from the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center

31 May 2017

Dutch scientists design self-destroying nanomotors to deliver and release drugs

Autonomous targeting and release of drugs at their site of action are desired features of nanomedical systems. Now, a team of Dutch scientists has designed a nanomotor that has these functions: An antitumor drug encapsulated in self-propelled, self-assembled stomatocytes is carried across the cellular membrane and released inside the cell upon a chemical redox signal that disassembles the vesicle membrane.

31 May 2017

Oxytocin treatment may help overcome drug addiction, study suggests

Many people have suggested that addiction hijacks the body's natural drives in the service of compulsive drug use.

31 May 2017

Pharmaceutical News

Recovery on the reservation: Montana sisters help peers stop using drugs

Aspirin may provide little or no benefit for certain patients with narrowed, hardened arteries

Diabetes medication can protect against cardiac stiffening in obese female mice

Opioid use gradually increases few years after bariatric surgery, study shows

Study: 1 in 6 patients on new blood-thinning medications may not be receiving recommended dose

Novartis, Bristol-Myers Squibb collaborate to examine combination therapies for metastatic colorectal cancer

Study finds increasing susceptibility of Staphylococcus aureus in U.S. hospital patients

Improved communication could help reduce unnecessary use of antibiotics for childhood illnesses

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

Study finds higher risk of fractures among older, long-term bisphosphonate users

UTI treatment with antibiotics for older adults may be more harmful than previously thought

Patients nearing end of life may not feel abandoned after discontinuation of cholesterol medications

Assessing safety and toxicity of bioactives could be key to establishing tolerable upper intake levels

UCSB biologists develop new antimicrobial susceptibility test to transform the way antibiotics are tested

Antidepressant use during pregnancy not linked to newborn problems at 2-4 weeks after birth

Study reveals key role of gut microbiota in treatment with classic diabetes medication

Study finds decline in rates of HPV-related precancerous cervical lesions among women in Connecticut

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

Dutch scientists design self-destroying nanomotors to deliver and release drugs

Oxytocin treatment may help overcome drug addiction, study suggests

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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