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$New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds$

New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds

A team of researchers of the University of Barcelona and the Hospital del Mar Medical Research Institute have discovered a new mutation that has an impact on the bone so that it is vulnerable to the bisphosphonate, a drug used to treat osteoporosis.

4 May 2017

Study finds no increase in muscle-related symptoms when patients are unaware of taking statin therapy

When patients were unaware they were taking statins there was no reported increase in muscle-related symptoms. But, when patients knew they were taking a statin, they were more likely to report symptoms, a finding consistent with the nocebo effect.

4 May 2017

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to demonstrate that this yeast had antibacterial properties against streptococcus bacteria.

4 May 2017

Discovery could help design better drugs to fight against antibiotic-resistant superbugs

Antibiotic resistance is a growing global health threat. So much so that a 2014 study commissioned by the Prime Minister of the United Kingdom predicted that, if the problem is left unchecked, in less than 35 years more people will die from antibiotic-resistant superbugs than from cancer.

4 May 2017

Steroids offer no additional relief to emergency patients suffering from hives

Despite standard use for the itching associated with urticaria (commonly known as hives), prednisone (a steroid) offered no additional relief to emergency patients suffering from hives than a placebo did, according to a randomized, placebo-controlled, double-blind, parallel-group study published online yesterday in Annals of Emergency Medicine.

4 May 2017

Study reveals safety data for using antimalarials during first trimester of pregnancy

Malaria is more common and severe in pregnant women, increasing their risk of miscarriage and other adverse outcomes. The adverse consequences of malaria in pregnancy require prompt, safe, and effective treatment.

3 May 2017

New treatment offers hope for kidney failure and transplant patients with rare disorder

A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys and leads to kidney failure, according to new research.

3 May 2017

Study provides evidence for antidepressant effects of ketamine

Better known as an anesthetic or as an illicit hallucinogenic drug, ketamine has also long been noted for alleviating depression. But ketamine has not been tested in a large clinical trial, and all evidence of its antidepressant effects has come from anecdotes and small studies of fewer than 100 patients.

3 May 2017

Zinc acetate and zinc gluconate lozenges show similar efficacy in shortening duration of common colds

There is no significant difference between zinc acetate lozenges and zinc gluconate lozenges regarding their efficacy in shortening the duration of common colds according to a meta-analysis published in Journal of the Royal Society of Medicine Open.

3 May 2017

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

A newly released study published in the Journal of Immunity, Inflammation and Disease and conducted by the Sapienza University of Rome, Italy, found a multi-strain, high concentration, probiotic formulation that helped reconstitute the physical and immunological integrity of the gastrointestinal lining in HIV-1-positive patients on antiretroviral therapy.

3 May 2017

Merck presents data on investigational cladribine tablets in relapsing multiple sclerosis

Merck announced the presentation of new analyses of efficacy and safety data for investigational Cladribine Tablets in poster presentations at the Annual Meeting of the American Academy of Neurology (AAN), that took place April 22 – 28, 2017, in Boston, Massachusetts.

3 May 2017

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Myriad Genetics, Inc. and Clovis Oncology, Inc. have announced a companion diagnostic collaboration to support a post-marketing regulatory commitment related to Clovis’ PARP inhibitor, Rubraca. Financial terms of the deal were not disclosed.

3 May 2017

Biologics prescribers collaborative releases new white paper: The State of Biosimilars Policy

The Biologics Prescribers Collaborative (BPC), a project of the Alliance for Patient Access, released a new white paper, “The State of Biosimilars Policy.” The paper is released in conjunction with a congressional briefing on Capitol Hill where experts will discuss the current biosimilars policy framework and its impact on prescribing, reimbursement and use.

3 May 2017

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Invivoscribe® Technologies Inc., a global company with more than 20 years of experience providing clonality and biomarker test solutions for the fields of oncology, personalized molecular diagnostics® and personalized molecular medicine®, today announces the premarket approval of LeukoStrat® CDx FLT3 Mutation Assay.

3 May 2017

Shire and Parion Sciences to collaborate on P-321 for ophthalmic indications

Shire plc and Parion Sciences, Inc. have announced they have entered into an agreement granting Shire exclusive worldwide rights to develop and commercialize P-321. Shire will lead development of P-321, an investigational epithelial sodium channel (ENaC) inhibitor for the potential treatment of dry eye disease in adults, with the opportunity for Parion to co-fund.

3 May 2017

Pharma supply chain "needs to get out of its silos"

This was the message from Alan Kennedy of TEAM-UP speaking at the 2017 LogiPharma Conference in Montreux on April 25th - 27th 2017. Kennedy said that the pharma supply chain needs to prioritise getting out of its silos and start working in unison to push and embrace fundamental structural reform.

3 May 2017

Molecular drug imaging likely to benefit children with brain tumors

Brain cancers are difficult to treat, and it can be hard to predict whether a therapy will be effective. When the patient is a child, it's even more important to predict the potential effectiveness of a drug before beginning treatment.

3 May 2017

Survey shows nearly 90% of patients on warfarin would like to self-monitor

Roche Diagnostics UK and Ireland launches the next generation of INR patient self-monitoring meter for people on warfarin anticoagulant therapy.

3 May 2017

PCSK9 Inhibitors: Highlights barriers to new, breakthrough cholesterol-lowering drugs

Today the Partnership to Advance Cardiovascular Health released a new web video, “PCSK9 Inhibitors: Access Barriers Affect Real People” The video, featuring patient testimonials, explores access issues to new, breakthrough cholesterol-lowering drugs known as PCSK9 inhibitors.

3 May 2017

NIST chemists publish new data on important compound’s thermodynamic properties

Amantadine hydrochloride may be the most common medication you've never heard of. This compound has been around for decades as the basis for antiviral and other medications, from flu therapy to treatments for brain disorders such as Parkinson's disease and the fatigue associated with multiple sclerosis.

2 May 2017

Pharmaceutical News

New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds

Study finds no increase in muscle-related symptoms when patients are unaware of taking statin therapy

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

Discovery could help design better drugs to fight against antibiotic-resistant superbugs

Steroids offer no additional relief to emergency patients suffering from hives

Study reveals safety data for using antimalarials during first trimester of pregnancy

New treatment offers hope for kidney failure and transplant patients with rare disorder

Study provides evidence for antidepressant effects of ketamine

Zinc acetate and zinc gluconate lozenges show similar efficacy in shortening duration of common colds

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

Merck presents data on investigational cladribine tablets in relapsing multiple sclerosis

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Biologics prescribers collaborative releases new white paper: The State of Biosimilars Policy

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Shire and Parion Sciences to collaborate on P-321 for ophthalmic indications

Pharma supply chain "needs to get out of its silos"

Molecular drug imaging likely to benefit children with brain tumors

Survey shows nearly 90% of patients on warfarin would like to self-monitor

PCSK9 Inhibitors: Highlights barriers to new, breakthrough cholesterol-lowering drugs

NIST chemists publish new data on important compound’s thermodynamic properties

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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