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New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections in Seattle, a leading annual conference of HIV research, clinical practice and progress.

24 Feb 2017

Scientists devise novel DNA vaccine approach against important cancer antigen targets

Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets. Study results were published in the journal Molecular Therapy.

24 Feb 2017

New investigational drug may help combat antibiotic-resistant global health threat

The deadly fungus, Candida auris, which has been found in hospitals, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected.

24 Feb 2017

Researchers find link between low general cognitive ability and elevated risk of not taking statins

After a heart attack, it is important for patients to take medication that lowers cholesterol levels. In a new study published in the European Journal of Preventive Cardiology, researchers at Uppsala and Umeå Universities have found that general cognitive ability (intelligence) has a bearing, in the first year and two years after the heart attack, on how well men take statins prescribed for them.

24 Feb 2017

Structure of unique amyloid fibrils could lead to discovery of new antibiotics

The highly pathogenic Staphylococcus aureus bacteria is one of the five most common causes of hospital-acquired infections. In the US alone, approximately 500,000 patients at hospitals contract a staph infection. It is the bacteria responsible for MRSA, for which there is no vaccine.

24 Feb 2017

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

A new study in rats suggests that nicotinamide riboside (NR), a form of vitamin B3, may be useful for treating or preventing nerve pain (neuropathy) caused by chemotherapy drugs.

24 Feb 2017

Study reveals promising therapeutic approach that can be beneficial for older melanoma patients

Scientists at The Wistar Institute have shown that an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved in metastatic progression and resistance to targeted therapies for the disease.

24 Feb 2017

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

A potentially life-saving treatment for sepsis has been under our noses for decades in the non-steroidal anti-inflammatory drugs most people have in their medicine cabinets, a new University of Colorado Boulder study suggests.

23 Feb 2017

New analysis finds high rates of initial medication non-adherence in chronic treatments

A new analysis indicates that not obtaining a medication the first time it is prescribed-called initial medication non-adherence-is common among patients within the Catalan health system in Spain.

23 Feb 2017

New compounds with potent anticancer activity could lessen side effects of oncological treatments

The Universitat Jaume I, the Spanish Centre for Advanced Scientific Research and the University of Pavia have patented new compounds with potent anticancer activity in breast and colon tumour cell lines that have low toxicity in healthy cells, which can dramatically decrease side effects during chemotherapy treatment.

23 Feb 2017

Wastewater releases from oil and gas operations at West Virginia alter microbes, study finds

Wastewater from oil and gas operations -- including fracking for shale gas -- at a West Virginia site altered microbes downstream, according to a Rutgers-led study.

23 Feb 2017

Chemists discover cheaper, faster way to identify and test new drugs

Chemists at the University of Waterloo, SCIEX and Pfizer have discovered a new way to help the pharmaceutical industry identify and test new drugs, which could revolutionize drug development, and substantially reduce the cost and time drugs need to reach their market.

23 Feb 2017

New compound kills whipworm more effectively than existing drugs

The human whipworm, which infects 500 million people and can damage physical and mental growth, is killed at egg and adult stage by a new drug class developed at the Universities of Manchester and Oxford and University College London.

From The University of Manchester 22 Feb 2017

Researchers develop new tool to help avoid adverse reactions to drugs

Researchers at the University of Liverpool, Alder Hey, University of Central Lancashire and University College London have developed a new tool to help avoid adverse reactions to medicines.

22 Feb 2017

Prolonged use of popular heartburn drugs linked to silent, gradual kidney damage

Taking popular heartburn drugs for prolonged periods has been linked to serious kidney problems, including kidney failure.

22 Feb 2017

Scientists unravel novel protein catalysts that can direct biosynthesis of hapalindole-type alkaloids

Alkaloids are natural nitrogen-containing compounds produced by plants and microbes. These molecules, such as morphine and quinine, are important human medicines.

22 Feb 2017

Anti-epilepsy medicine use during pregnancy does not harm overall health of children, study finds

Children whose mothers have taken anti-epilepsy medicine during pregnancy, do not visit the doctor more often than children who have not been exposed to this medicine in utero. This is the result of a new study from Aarhus.

21 Feb 2017

Scientists identify novel mutations in bacteria that promote evolution of antibiotic resistance

Scientists from the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, have identified novel mutations in bacteria that promote the evolution of high-level antibiotic resistance.

21 Feb 2017

Pitt researchers uncover genetic marker that may predict drug response in many cancer types

Researchers at the University of Pittsburgh School of Medicine have uncovered a novel genetic mechanism of thyroid cancer, as well as a marker that may predict response to a particular class of drugs, not just in patients with thyroid cancer, but in those with many other types of cancer as well.

21 Feb 2017

Cocaine addiction may disrupt iron regulation in the brain, study finds

Cocaine addiction may affect how the body processes iron, leading to a build-up of the mineral in the brain, according to new research from the University of Cambridge.

21 Feb 2017

Pharmaceutical News

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Scientists devise novel DNA vaccine approach against important cancer antigen targets

New investigational drug may help combat antibiotic-resistant global health threat

Researchers find link between low general cognitive ability and elevated risk of not taking statins

Structure of unique amyloid fibrils could lead to discovery of new antibiotics

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

Study reveals promising therapeutic approach that can be beneficial for older melanoma patients

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

New analysis finds high rates of initial medication non-adherence in chronic treatments

New compounds with potent anticancer activity could lessen side effects of oncological treatments

Wastewater releases from oil and gas operations at West Virginia alter microbes, study finds

Chemists discover cheaper, faster way to identify and test new drugs

New compound kills whipworm more effectively than existing drugs

Researchers develop new tool to help avoid adverse reactions to drugs

Prolonged use of popular heartburn drugs linked to silent, gradual kidney damage

Scientists unravel novel protein catalysts that can direct biosynthesis of hapalindole-type alkaloids

Anti-epilepsy medicine use during pregnancy does not harm overall health of children, study finds

Scientists identify novel mutations in bacteria that promote evolution of antibiotic resistance

Pitt researchers uncover genetic marker that may predict drug response in many cancer types

Cocaine addiction may disrupt iron regulation in the brain, study finds

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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