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Experimental drug may prevent development of multiple sclerosis in mice

The experimental drug laquinimod may prevent the development or reduce the progression of multiple sclerosis (MS) in mice, according to research published in the September 21, 2016, online issue of Neurology Neuroimmunology & Neuroinflammation, a medical journal of the American Academy of Neurology.

21 Sep 2016

Bile acid transporter inhibitors can prevent NASH in mice, study shows

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children's Healthcare of Atlanta have shown.

21 Sep 2016

TSRI scientists shed light on molecular workings of MS drug

A study by scientists at The Scripps Research Institute has helped to de-mystify the molecular workings of the multiple sclerosis (MS) drug Tecfidera. The drug is the most widely prescribed pill-based therapy for MS, but its biological mechanism remains mysterious.

21 Sep 2016

Duke researchers discover blood markers linked to drug-resistant tumor cells

While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with tumor resistance to two common hormone therapies.

21 Sep 2016

Common genetic variant reduces neurobiological benefits of exercise in mice

A new study revealed that a common genetic variant in the brain-derived neurotrophic factor gene reduces the neurobiological benefits induced by physical exercise in mice.

21 Sep 2016

Inhealthcare introduces first self-testing mobile app for warfarin users

Digital health specialist Inhealthcare is bringing to market the first self-testing mobile app for warfarin users that connects directly to doctors.

From Inhealthcare Limited 21 Sep 2016

LARC benefits wider population of potential users than previously thought

New research provides strong scientific evidence that long-acting reversible contraception (LARC) benefits a wider population of potential users than previously thought.

21 Sep 2016

New partnership between BetterYou and University of Sheffield paves way for vitamin D research

A new collaboration between health pioneers BetterYou and scientists from the University of Sheffield, is paving the way for a three-year clinical trial looking at the effect of vitamin D supplementation on the quality of life of people with Irritable Bowel Syndrome (IBS).

From BetterYou Ltd 21 Sep 2016

Study of classical Chinese medical literature finds references similar to Alzheimer's disease

A new study of classical Chinese medical texts identifies references to age-related memory impairment similar to modern-day Alzheimer's disease, and to several plant-based ingredients used centuries ago -- and still in use today -- to treat memory impairment.

20 Sep 2016

Mice study explains why antidepressants don't work in some patients

SSRI antidepressants (Selective Serotonin Reuptake Inhibitors, the best known being Prozactm) are amongst the most commonly taken medicines.

20 Sep 2016

Crick researchers find promising target for new tuberculosis drugs

Scientists led by Dr Luiz Pedro Carvalho at the Francis Crick Institute in London have found a promising new target in the search for new tuberculosis drugs. In the process, they say they've proven the strengths of a new research technique called metabolomics.

20 Sep 2016

Human pluripotent stem cells may revolutionize drug discovery in heart disease

Coaxing stem cells from patients to become heart cells may help clinicians personalize drug treatments and prevent heart-related toxicity.

20 Sep 2016

Guidelines for staying healthy during flu season

The American Academy of Pediatrics updated its annual influenza (flu) season guidelines, withdrawing the child-friendly nasal flu vaccine, FluMist, this year.

20 Sep 2016

New study finds opioid dependence affects perception of cute images of babies

A new pilot study has found that opioid dependence - which includes dependence on drugs such as heroin - affects how 'cute' we perceive images of children to be.

19 Sep 2016

$New therapy for osteoporosis provides protection against bone fractures in postmenopausal women$

New therapy for osteoporosis provides protection against bone fractures in postmenopausal women

A recent analysis of results from a randomized controlled clinical trial indicates that abaloparatide-SC, a novel therapy for osteoporosis, provides consistent protection against bone fractures in postmenopausal women with osteoporosis regardless of their baseline bone density, age, and previous history of fracture.

19 Sep 2016

Study quantifies burden of clinically impactful ADRs in general adult population

In a study of 1000 adult patients with unplanned admission to a tertiary hospital in Singapore, the prevalence of adverse drug reactions (ADRs) at the time of admission was 12.4 percent, and the prevalence of ADRs causing admission to the hospital was 8.1 percent.

19 Sep 2016

Sarepta Therapeutics wins accelerated approval from FDA for Duchenne muscular dystrophy drug

The U.S. Food and Drug Administration today approved Exondys 51 (eteplirsen) injection, the first drug approved to treat patients with Duchenne muscular dystrophy (DMD).

19 Sep 2016

Researchers discover new strategy to boost effectiveness of anti-cancer immune therapy

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to maximize the effectiveness of anti-cancer immune therapy.

19 Sep 2016

Study shows clot-busting drug safe in treating people with wake-up stroke

Using a clot-busting medication to treat people who wake up with symptoms of stroke was safe and should be studied further to see how effective it might be for a population that otherwise has few treatment options, according to researchers at The University of Texas Health Science Center at Houston.

19 Sep 2016

Benefits of cardioprotective drugs may extend beyond preventing acute coronary syndromes

Medications prescribed to prevent heart attacks such as statins and aspirin are also associated with reduced heart attack severity, according to research published in PLOS ONE.

19 Sep 2016