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BET inhibitors could be powerful new therapeutic strategy for ovarian cancer

Few effective treatments have been approved to treat ovarian cancer, the deadliest of all cancers affecting the female reproductive system.

14 Sep 2016

Study shows holes in HIV's protective glycan shield could be vital in designing vaccine candidates

A new study from scientists at The Scripps Research Institute shows that "holes" in HIV's defensive sugar shield could be important in designing an HIV vaccine.

14 Sep 2016

Liquid crystal technique could be new way to control drug delivery process

Liquid crystals are strange substances, both fish and fowl. They can flow like a liquid, but have the orderly molecular structure of a crystalline solid. And that internal structure can be changed by small cues from outside.

13 Sep 2016

ATR inhibitors show improved survival and effectiveness in animal models of cancer

Tumours are an accumulation of cells that divide without control, accumulating hundreds of chromosomal alterations and mutations in their DNA.

13 Sep 2016

New study to look at impact of common antidepressants on pregnant women

Northwestern Medicine Prentice Women's Hospital and the Northwestern University Feinberg School of Medicine Department of Psychiatry is home to a landmark study that will, for the first time, take a close look at the impact of certain common antidepressants on pregnant women.

13 Sep 2016

Chemists develop one-step solution to make precursors for synthesis of drugs

A one-step solution to make nitrogen-laden molecular precursors for the preparation of drugs and other bioactive molecules has been discovered by researchers at Rice University, the University of Texas Southwestern Medical Center and Brigham Young University.

13 Sep 2016

TSRI, IAVI scientists reveal new reductionist vaccine strategy to fight against HIV

A series of new studies led by scientists at The Scripps Research Institute and the International AIDS Vaccine Initiative describe a potential vaccination strategy to jump-start the selection and evolution of broadly effective antibodies to prevent HIV infection.

13 Sep 2016

Nanoparticles shaped like rods and worms could effectively deliver drugs, research suggests

When it comes to delivering drugs, nanoparticles shaped like rods and worms are the best bet for making the daunting journey to the centre of a cell, new Australian research suggests.

13 Sep 2016

Research provides scientific evidence for adverse effects of cannabis intake on brain development

Researchers have clarified important mechanisms involved in the formation of neural circuits in the brain.

13 Sep 2016

Psychotropic drugs cannot alleviate symptoms of mental disorders, say researchers

Drugs don't lead to sustainable alleviation of mental disorders, as the psychologists Prof Dr Jürgen Margraf and Prof Dr Silvia Schneider claim in a commentary published in "EMBO Molecular Medicine".

12 Sep 2016

Study provides insight into how weight-loss drug acts in the brain

A weight-loss drug dampened the response to food cues in regions of the brain associated with attention and emotion, leading to decreases in caloric intake, weight and body mass index (BMI), a team led by scientists at Beth Israel Deaconess Medical Center reported.

12 Sep 2016

Anaesthetic known for surgical procedures may be quick remedy for depression

Vienna and MedUni Vienna are currently the hotspot for brain health: this coming Thursday, the very first "Brain Day" will be held for a lay audience in the Van Swieten Hall of the Medical University of Vienna.

12 Sep 2016

New study raises safety concerns on clinical use of caspase inhibitors for liver diseases

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase. Caspase inhibitors have therapeutic potential to treat and prevent apoptosis-mediated liver injury, and some are currently in clinical trials.

9 Sep 2016

CHORI scientists reveal improved protective antibody responses to new meningococcal vaccine

A study conducted by UCSF Benioff Children's Hospital Oakland Research Institute scientists shows greatly improved protective antibody responses to a new mutant vaccine antigen for prevention of disease caused by Neisseria meningitidis - also known as meningococcus - that has the potential to improve the current vaccines for meningitis.

9 Sep 2016

New research could pave way for safe, effective treatment for muscular dystrophy

New research has shown that the corticosteroid deflazacort is a safe and effective treatment for Duchenne muscular dystrophy. The findings, which appear this month in the journal Neurology, could pave the way for first U.S.-approved treatment for the disease.

9 Sep 2016

Steroids for treating infertility in women may have harmful effects on pregnancy and child

Researchers at the University of Adelaide are urging doctors and patients to refrain from using a specific steroid treatment to treat infertility in women unless clinically indicated, because of its links to miscarriage, preterm birth and birth defects.

9 Sep 2016

New mouse model helps identify potential drug target for hard-to-treat social aspects of ASD

A study of a new mouse model identifies a drug target that has the potential to increase social interaction in individuals with some forms of autism spectrum disorder (ASD), according to researchers in the Perelman School of Medicine at the University of Pennsylvania. The team published their work in Biological Psychiatry.

9 Sep 2016

Pharmaceutical News

BET inhibitors could be powerful new therapeutic strategy for ovarian cancer

Study shows holes in HIV's protective glycan shield could be vital in designing vaccine candidates

Liquid crystal technique could be new way to control drug delivery process

ATR inhibitors show improved survival and effectiveness in animal models of cancer

New study to look at impact of common antidepressants on pregnant women

Chemists develop one-step solution to make precursors for synthesis of drugs

TSRI, IAVI scientists reveal new reductionist vaccine strategy to fight against HIV

Nanoparticles shaped like rods and worms could effectively deliver drugs, research suggests

Research provides scientific evidence for adverse effects of cannabis intake on brain development

Psychotropic drugs cannot alleviate symptoms of mental disorders, say researchers

Study provides insight into how weight-loss drug acts in the brain

Anaesthetic known for surgical procedures may be quick remedy for depression

New study raises safety concerns on clinical use of caspase inhibitors for liver diseases

CHORI scientists reveal improved protective antibody responses to new meningococcal vaccine

New research could pave way for safe, effective treatment for muscular dystrophy

Steroids for treating infertility in women may have harmful effects on pregnancy and child

New mouse model helps identify potential drug target for hard-to-treat social aspects of ASD

UC researchers offer more insights into how lack of gut bacteria influences fat absorption

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

Research could pave way for more effective and safer anti-epilepsy drugs

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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