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DZNE scientists find new mechanism that allows damaged neurons to regenerate

Injuries to the spinal cord can cause paralysis and other permanent disabilities because severed nerve fibers do not regrow. Now, scientists of the German Center for Neurodegenerative Diseases have succeeded in releasing a molecular brake that prevents the regeneration of nerve connections.

7 Oct 2016

Study finds neoadjuvant immunotherapy safe, viable for early lung cancer patients before surgery

Neoadjuvant immunotherapy with the PD-1 inhibitor nivolumab is safe and feasible prior to surgery for early lung cancer, researchers reported at the ESMO 2016 Congress in Copenhagen.

7 Oct 2016

IDRI awarded two-year NIH grant to develop novel RNA-based Zika virus vaccine

As Zika cases continue to rise around the world -- and in the United States -- with associated increases in Guillain-Barre syndrome and congenital birth defects, the need for a safe and effective vaccine to protect against Zika virus is greater than ever.

6 Oct 2016

Penn Medicine awarded CDC grant to develop new approaches to combat antibiotic resistance

The Perelman School of Medicine at the University of Pennsylvania has been awarded more than $1 million by the U.S. Centers for Disease Control and Prevention (CDC) to develop new approaches to combat antibiotic resistance.

6 Oct 2016

Combination therapy for melanoma has added benefit in certain patients

Nivolumab in combination with ipilimumab has been approved since May 2016 for adults with advanced melanoma. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this drug offers an added benefit.

6 Oct 2016

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

As demand for the widely used blood thinning drug heparin continues to grow, experts worry of possible shortages of the essential medication.

6 Oct 2016

Genetic risk for mental illness linked to substance use and addiction

There are many reports of drug use leading to mental health problems, and we all know of someone having a few too many drinks to cope with a bad day.

6 Oct 2016

Researcher investigates ethics of maternal immunization

Vaccination during pregnancy can protect women, foetuses and newborn children against infectious diseases - especially in developing countries. Maternal immunisation however also raises ethical questions.

6 Oct 2016

Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of Texas MD Anderson Cancer Center.

5 Oct 2016

Scientists report early-stage development of potential nerve agent antidote

Nerve agents are molecular weapons that invade the body and sabotage part of the nervous system, causing horrific symptoms and sometimes death within minutes. Few antidotes exist, and those that do must be administered soon after an attack.

5 Oct 2016

Many gay and bisexual men unaware that PrEP medication may reduce HIV risk

Only four in 10 gay and bisexual men in Baltimore without HIV are aware that pre-exposure prophylaxis medication (PrEP) may significantly reduce their risk of contracting the virus, even those who had recently visited a doctor or been tested for a sexually transmitted disease, new Johns Hopkins Bloomberg School of Public Health research suggests.

5 Oct 2016

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata--an autoimmune disease that causes patchy, and less frequently, total hair loss--had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

5 Oct 2016

BBI Solutions launches new range of antibodies for Galectin-3 biomarker

BBI Solutions has announced the launch of a range of antibodies for the biomarker Galectin-3. The antibodies complement BBI’s Galectin-3 antigen, which was also launched earlier this year.

5 Oct 2016

Scientists identify new pathway in the brain that can be targeted to alleviate depression

Northwestern Medicine scientists have discovered a new pathway in the brain that can be manipulated to alleviate depression. The pathway offers a promising new target for developing a drug that could be effective in individuals for whom other antidepressants have failed.

5 Oct 2016

New type of nanoparticles can deliver chemotherapy efficiently to cancer cells

Engineering researchers at The University of Texas at Austin have developed a new method that delivers chemotherapy directly and efficiently to individual cells.

4 Oct 2016

Prescription sleep aids may stimulate suicidal thoughts or actions

Prescription sleep aids appear to carry a rare risk of suicide, most typically when they cause the unexpected response of stimulating rather than quietening patients, researchers say.

4 Oct 2016

Two Zika vaccine candidates protect newborn mice against neurological damage

Two vaccines against Zika virus developed at the University of Pittsburgh School of Medicine have successfully conveyed immunity from female mice to pups conceived weeks after the mother's vaccination.

4 Oct 2016

Diabetes patients do not absorb insulin effectively when injecting into lipohypertrophy, confirm new studies

Two new studies provide evidence for the first time that insulin is not absorbed effectively when injected into Lipohypertrophy (LH).

4 Oct 2016

Study shows how common intestinal microbe protects the gut from attack by harmful bacteria

Antibiotics save millions of lives. But their tendency to kill helpful and harmful bacteria alike, coupled with the growing problem of antibiotic resistance, means that they are not without their downside.

4 Oct 2016

Antiseptic used for umbilical cord care ineffective in reducing newborn deaths in Africa

Despite significant reductions in neonatal mortality previously reported in south Asia, applying a chlorhexidine wash to newborns' umbilical cords in sub-Saharan Africa did not reduce deaths, a study led by researchers from the Boston University School of Public Health shows.

4 Oct 2016

Pharmaceutical News

DZNE scientists find new mechanism that allows damaged neurons to regenerate

Study finds neoadjuvant immunotherapy safe, viable for early lung cancer patients before surgery

IDRI awarded two-year NIH grant to develop novel RNA-based Zika virus vaccine

Penn Medicine awarded CDC grant to develop new approaches to combat antibiotic resistance

Combination therapy for melanoma has added benefit in certain patients

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

Genetic risk for mental illness linked to substance use and addiction

Researcher investigates ethics of maternal immunization

Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

Scientists report early-stage development of potential nerve agent antidote

Many gay and bisexual men unaware that PrEP medication may reduce HIV risk

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

BBI Solutions launches new range of antibodies for Galectin-3 biomarker

Scientists identify new pathway in the brain that can be targeted to alleviate depression

New type of nanoparticles can deliver chemotherapy efficiently to cancer cells

Prescription sleep aids may stimulate suicidal thoughts or actions

Two Zika vaccine candidates protect newborn mice against neurological damage

Diabetes patients do not absorb insulin effectively when injecting into lipohypertrophy, confirm new studies

Study shows how common intestinal microbe protects the gut from attack by harmful bacteria

Antiseptic used for umbilical cord care ineffective in reducing newborn deaths in Africa

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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Bioprocess Efficiency with Cell Density Monitoring

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