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Researchers develop versatile building blocks that could be useful in pharmaceutical research

Researchers in the Doyle lab at Princeton have developed a direct cross-coupling reaction to produce nitrogen-containing compounds called 1,2-dihydropyridines, versatile building blocks that are highly useful in pharmaceutical research.

24 Mar 2016

New project aims to prevent complications from drug usage

If a patient is ill and takes drugs for that illness, these drugs often lead to further illnesses and complications. This affects millions of people throughout the world.

24 Mar 2016

Study shows fish oil supplements make no significant difference to muscle growth

The effect of fish oil supplements on muscle growth has been investigated by a team of Stirling academics, revealing the tablets do not give gym-goers an advantage in the weight room.

24 Mar 2016

Chinese medicines may contain hazardous chemicals

Chinese medicines are manufactured and distributed all over the world. Many people perceive them as natural, even benign and with few side effects, but regulation of human medicines fluctuates widely in different countries.

24 Mar 2016

Anticonvulsant medication gabapentin effectively reduces common complication of PONV

The anticonvulsant medication gabapentin—already a useful part of strategies to control pain after surgery—also effectively reduces the common complication of postoperative nausea and vomiting (PONV), reports a study in Anesthesia & Analgesia.

23 Mar 2016

FDA announces required class-wide safety labeling changes for IR opioid pain medications

In a continuing effort to educate prescribers and patients about the potential risks related to opioid use, the U.S. Food and Drug Administration today announced required class-wide safety labeling changes for immediate-release (IR) opioid pain medications. Among the changes, the FDA is requiring a new boxed warning about the serious risks of misuse, abuse, addiction, overdose and death.

23 Mar 2016

Cinqair (reslizumab) approved for treatment of severe asthma

The U.S. Food and Drug Administration today approved Cinqair (reslizumab) for use with other asthma medicines for the maintenance treatment of severe asthma in patients aged 18 years and older. Cinqair is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines.

23 Mar 2016

Targeted therapies suppress T cell activity that could actually help fight tumors

In many cases, targeted therapies for cancer are preferred as treatments over chemotherapy and surgery because they attack and kill cancer cells with specific tumor-promoting mutations while sparing healthy, normal cells that do not express these mutations.

23 Mar 2016

DAA medication could lead to revolution in hepatitis C treatment

The cost of treating hepatitis C virus (HCV) could be cut up to 50 percent if mathematical models are used to predict when patients can safely stop taking direct-acting antiviral (DAA) medication, according to a new study by researchers at Loyola University Health System and Loyola University Chicago

23 Mar 2016

New research links antibiotic use before age 2 to childhood obesity

While early antibiotic use has been associated with a number of rare long-term health consequences, new research links antibiotics to one of the most important and growing public health problems worldwide -- obesity.

23 Mar 2016

Antipsychotic medications may not be effective in preventing delirium in hospitalized patients

A recent review of the medical literature does not support the use of antipsychotic medications for preventing or treating delirium in hospitalized patients.

23 Mar 2016

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Vaginal transmission accounts for the majority of new HIV infections worldwide. Forms of pre-exposure prophylaxis (PrEP) such as vaginal gels and vaginal rings designed to prevent HIV transmission have encountered poor efficacy in human trials due to problems with adherence.

22 Mar 2016

Tiny gel slivers open way to personalised cancer treatment targeting particular tumour

They look like small, translucent gems but these tiny 'gel' slivers hold the world of a patient's tumour in microcosm ready for trials of anti-cancer drugs to find the best match between treatment and tumour.

22 Mar 2016

Scientists look for new antibiotic drugs in unexpected places

Many of the drugs we use in hospitals – antibiotics, antifungals and anti-cancer drugs, to name but a few – are produced by bacteria that live in the soil beneath our feet.

22 Mar 2016

Mycophenolate mofetil drug seems safe, effective in treating autoimmune hepatitis

New research indicates that mycophenolate mofetil, a drug that is usually used to prevent rejection after kidney, heart or liver transplant, seems safe and effective in treating autoimmune hepatitis (AIH), a serious chronic liver disease that mainly affects women.

22 Mar 2016

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

At least half of Parkinson's disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients.

21 Mar 2016

Anthim (obiltoxaximab) injection approved for treatment of inhalational anthrax

On Friday, March 18, the U.S. Food and Drug Administration approved Anthim (obiltoxaximab) injection to treat inhalational anthrax in combination with appropriate antibacterial drugs. Anthim is also approved to prevent inhalational anthrax when alternative therapies are not available or not appropriate.

21 Mar 2016

Real-world studies support switching IBD patients from reference infliximab to biosimilar infliximab

Data presented today at the 11th Congress of European Crohn’s and Colitis Organisation adds to the growing body of real-world evidence that supports switching patients from reference infliximab to biosimilar infliximab.

21 Mar 2016

LEO Pharma announces scientific approval of Enstilar for treatment of people living with psoriasis in EU

LEO Pharma today announced that it received scientific approval of Enstilar (calcipotriol/betamethasone dipropionate 50 micrograms/g / 0,5 mg/g) for the treatment of psoriasis vulgaris in patients 18 years of age or older.

21 Mar 2016

Women taking birth control pill less likely to suffer serious knee injuries

Researchers from The University of Texas Medical Branch at Galveston have found that women who take the birth control pill, which lessen and stabilize estrogen levels, were less likely to suffer serious knee injuries. The findings are currently available in Medicine & Science in Sports & Exercise, the official journal of the American College of Sports Medicine.

21 Mar 2016

Pharmaceutical News

Researchers develop versatile building blocks that could be useful in pharmaceutical research

New project aims to prevent complications from drug usage

Study shows fish oil supplements make no significant difference to muscle growth

Chinese medicines may contain hazardous chemicals

Anticonvulsant medication gabapentin effectively reduces common complication of PONV

FDA announces required class-wide safety labeling changes for IR opioid pain medications

Cinqair (reslizumab) approved for treatment of severe asthma

Targeted therapies suppress T cell activity that could actually help fight tumors

DAA medication could lead to revolution in hepatitis C treatment

New research links antibiotic use before age 2 to childhood obesity

Antipsychotic medications may not be effective in preventing delirium in hospitalized patients

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Tiny gel slivers open way to personalised cancer treatment targeting particular tumour

Scientists look for new antibiotic drugs in unexpected places

Mycophenolate mofetil drug seems safe, effective in treating autoimmune hepatitis

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

Anthim (obiltoxaximab) injection approved for treatment of inhalational anthrax

Real-world studies support switching IBD patients from reference infliximab to biosimilar infliximab

LEO Pharma announces scientific approval of Enstilar for treatment of people living with psoriasis in EU

Women taking birth control pill less likely to suffer serious knee injuries

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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