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Study finds no beneficial effect of cancer medication on Alzheimer's disease

The cancer medication bexarotene, aka Targretin, made headlines when researchers reported that it quickly lowered Aβ in the brain, reduced amyloid plaques, and improved learning and memory in mice that mimic salient features of Alzheimer's disease (AD).

16 Feb 2016

‘Adherent’ patients no better than ‘non-adherent" peers at taking their medication

A study at Universidad Miguel Hernández (UMH) in Elche shows that patients defined automatically as "adherent" by dint of their collecting their prescriptions each month are not necessarily any better than their "non-adherent" peers at actually taking their medication.

16 Feb 2016

Amgen announces availability of Kyprolis (carfilzomib) in the UK for treatment of relapsed multiple myeloma

Amgen today announced that Kyprolis in combination with lenalidomide and dexamethasone is now available in the UK for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.

16 Feb 2016

CMV-based vaccine provides protection against Ebola virus

As the latest in a series of studies, researchers at Plymouth University, National Institutes of Health and University of California, Riverside, have shown the ability of a vaccine vector based on a common herpesvirus called cytomegalovirus (CMV) expressing Ebola virus glycoprotein (GP), to provide protection against Ebola virus in the experimental rhesus macaque, non-human primate (NHP) model.

16 Feb 2016

Balancing supplementation with sunshine can help improve vitamin D levels

Health pioneers BetterYou have welcomed new guidance by the National Institute for Health and Care Excellence (NICE) highlighting that many adults in Britain have low levels of vitamin D and that some exposure to sunlight can help to build this up.

From BetterYou Ltd 15 Feb 2016

Bad technology choices contributing to increased drug development costs, say experts

The search for new medicines is becoming unsustainably expensive despite huge technological advances because researchers are using the wrong methods, experts say.

15 Feb 2016

Anti-cancer drug delays onset of Alzheimer's disease

Researchers have identified a drug that targets the first step in the toxic chain reaction leading to the death of brain cells, suggesting that treatments could be developed to protect against Alzheimer's disease, in a similar way to how statins are able to reduce the risk of developing heart disease.

15 Feb 2016

Protein Sciences, UNIGEN agree to supply Flublok influenza vaccine for the U.S. market from Japan

Protein Sciences Corporation (Meriden, CT and Pearl River, NY) and UMN Pharma Inc. (Akita, Akita prefecture, Japan) announced today that Protein Sciences and UNIGEN Inc., a joint venture of UMN and IHI Corporation (Koto-ku, Tokyo, Japan), entered into an agreement to source bulk Flublok influenza vaccine from Japan for the U.S. market.

12 Feb 2016

Marijuana use among U.S. adults not as high as predicted before

Marijuana use is on the rise, with an estimated 12.5 percent of adults living in the United States reportedly using the drug at least once in 2013, according to a new study that looked at drug usage over the span of a decade.

12 Feb 2016

Study confirms no detectable difference when switching between generics

While approved generics are required to be equivalent to their brand-named counterparts in terms of active ingredients, some may wonder if a switch between generics could cause problems for someone who relies on daily medication to control a severe, chronic condition, like seizures.

12 Feb 2016

CNIO researchers reveal how combination of dasatinib and demcizumab reduces lung adenocarcinomas

Lung cancer is one of the most prevalent types of cancer, with more than 20,000 new cases diagnosed each year in Spain. Lung adenocarcinomas carrying oncogenic KRAS, the engine driving these tumours in 30% of cases, constitute the most aggressive sub-type because, unlike other types of lung cancer, there are no targeted therapies beyond the standard cisplatin-based treatment.

12 Feb 2016

Leeds scientists to start computer drug research to find cure for Ebola virus

Scientists at the University of Leeds will run the equivalent of password cracking software to find the chemical keys to defeating the Ebola virus.

11 Feb 2016

CMU researchers create robotically-driven experimentation system to reduce drug discovery cost

Researchers from Carnegie Mellon University have created the first robotically driven experimentation system to determine the effects of a large number of drugs on many proteins, reducing the number of necessary experiments by 70 percent.

11 Feb 2016

Penn investigators explore new treatment option for cocaine dependence

In the ongoing fight against drug addiction, researchers from the University of Pennsylvania's School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug currently used for obese patients and type 2 diabetics: treatment for cocaine dependence.

11 Feb 2016

TSRI scientists develop new screening device for drug discovery

Screening large "libraries" of compounds to find those with a desired biological activity is a powerful method for discovering new drugs, but requires a large, expensive and dedicated facility. Now, scientists at the Florida campus of The Scripps Research Institute have devised the central component of a screening system that would be orders of magnitude smaller and cheaper.

11 Feb 2016

Fasudil improves memory in rats, promotes degradation of toxic tau in the eyes of fruit flies

Could a kinase inhibitor some doctors prescribe to keep blood flowing after brain surgery be used to treat neurodegeneration? New research suggests it might be worth exploring the question.

10 Feb 2016

Cranberry capsules more effective in lowering UTI risk than juice

A UTI is an infection in any part of the urinary system, kidneys, bladder or urethra. They are more common in women and affect more than 3 million Americans per year. Many in the population will turn to sipping on a cranberry juice cocktail to alleviate their symptoms, but, according to a Texas A&M Health Science Center urologist, drinking cranberry juice to treat a UTI is little more than an old wives' tale.

10 Feb 2016

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

A first-ever interlaboratory study of four versions of a therapeutic protein drug—all manufactured from living cells—reports that an established analytical tool akin to magnetic resonance imaging reliably assessed the atomic structures of the biologically similar products, yielding the equivalent of a fingerprint for each.

10 Feb 2016

Alternatives exist to eliminate nonmedical exemptions for childhood vaccination

For more than 30 years, Mississippi and West Virginia were the only states in the country that disallowed nonmedical exemptions to mandatory school vaccination laws for religious or philosophical reasons, until they were joined by California last year. These exemption laws have provoked debate over the rights of parents versus the responsibility of government to protect public health.

9 Feb 2016

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research.

9 Feb 2016

Pharmaceutical News

Study finds no beneficial effect of cancer medication on Alzheimer's disease

‘Adherent’ patients no better than ‘non-adherent" peers at taking their medication

Amgen announces availability of Kyprolis (carfilzomib) in the UK for treatment of relapsed multiple myeloma

CMV-based vaccine provides protection against Ebola virus

Balancing supplementation with sunshine can help improve vitamin D levels

Bad technology choices contributing to increased drug development costs, say experts

Anti-cancer drug delays onset of Alzheimer's disease

Protein Sciences, UNIGEN agree to supply Flublok influenza vaccine for the U.S. market from Japan

Marijuana use among U.S. adults not as high as predicted before

Study confirms no detectable difference when switching between generics

CNIO researchers reveal how combination of dasatinib and demcizumab reduces lung adenocarcinomas

Leeds scientists to start computer drug research to find cure for Ebola virus

CMU researchers create robotically-driven experimentation system to reduce drug discovery cost

Penn investigators explore new treatment option for cocaine dependence

TSRI scientists develop new screening device for drug discovery

Fasudil improves memory in rats, promotes degradation of toxic tau in the eyes of fruit flies

Cranberry capsules more effective in lowering UTI risk than juice

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

Alternatives exist to eliminate nonmedical exemptions for childhood vaccination

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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