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ICS use may lower risk of mortality from pneumonia and other causes in COPD patients

Treatment of COPD with inhaled corticosteroids (ICS) may decrease the risk of dying from pneumonia and from other causes despite being associated with an increase in the occurrence of pneumonia, according to a new meta-analysis presented at the 2015 American Thoracic Society International Conference.

21 May 2015

Canada lagging behind similar OECD countries with regard to public drug plan reimbursement

Canadians face wait times of over 460 days in order to get access to new, potentially lifesaving medicines in public drug plans, according to a new IMS Brogan report commissioned by Rx&D. Overall, the report ranks Canada 16 out of 18 similar OECD countries.

21 May 2015

FDA accepts Tris Pharma's Dyanavel XR NDA for review

Tris Pharma, Inc. announced that U.S. Food and Drug Administration has accepted for review its New Drug Application ("NDA") for Dyanavel XR (amphetamine) CII, an Extended-Release Oral Suspension.

21 May 2015

Enterprise Therapeutics secures additional funding to accelerate drug discovery for treatment of respiratory diseases

ENTERPRISE THERAPEUTICS Ltd, a drug discovery company focused on new therapeutics for respiratory diseases, today announced that it has secured an additional £2.4m ($3.6m) in Series-A financing.

21 May 2015

Second-generation antibiotic shows promise against common bacterial infections

Researchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness against common bacterial infections that pose a serious health threat to children and adults.

21 May 2015

HQO report shows variations across Ontario's long-term care homes regarding antipsychotic drug use

There are major differences across Ontario's long-term care homes in the percentage of residents who are being prescribed antipsychotic medications, according to Looking for Balance, a report from Health Quality Ontario, the provincial advisor on health care quality.

20 May 2015

New data shows safety and efficacy of biosimilar infliximab treatment in IBD patients

Clinical experience of biosimilar infliximab in 78 inflammatory bowel disease (IBD) patients presented at Digestive Diseases Week (DDW) 2015 in Washington D.C. showed that the treatment is comparable to the reference medicinal product (RMP) in terms of efficacy and safety.

20 May 2015

Omega-3 fatty acids improve cognitive flexibility in older adults at risk of late-onset Alzheimer's disease

A study of older adults at risk of late-onset Alzheimer's disease found that those who consumed more omega-3 fatty acids did better than their peers on tests of cognitive flexibility -- the ability to efficiently switch between tasks -- and had a bigger anterior cingulate cortex, a brain region known to contribute to cognitive flexibility.

20 May 2015

New UCLA study finds Naltrexone drug as promising treatment for methamphetamine addiction

A new study by UCLA researchers has found that Naltrexone, a drug used to treat alcoholism, may also be a promising treatment for addiction to methamphetamine.

19 May 2015

Twin Cities Orthopedics joins Deterra partnership program to reduce prescription drug abuse and misuse

Verde Technologies announced that Golden Valley-based Twin Cities Orthopedics, the largest orthopedic group in Minnesota, has become its most recent partner in the fight against prescription drug abuse and misuse.

19 May 2015

Short course of oral steroids unlikely to provide much benefit for patients with acute sciatica

Among patients with acute sciatica caused by a herniated lumbar disk (a condition also known as "acute radiculopathy"), a short course of oral steroids resulted in only modest improvement in function and no significant improvement in pain, according to a study published today in the Journal of the American Medical Association.

19 May 2015

Lakewood-Amedex's novel class of antimicrobials prove effective at killing MDR-TB strains

Lakewood-Amedex Inc., a leading developer of novel anti-infective pharmaceuticals, announced today that a recent series of in vitro studies conducted by Southern Research in Birmingham, Alabama, have demonstrated that its novel class of antimicrobials, named bisphosphocins, have proven effective at killing multidrug-resistant (MDR) strains of Mycobacterium tuberculosis, the bacteria responsible for the chronic lung infection tuberculosis.

19 May 2015

Current menopausal hormone therapy users at increased risk of experiencing GI bleeding

Current users of menopausal hormone therapy (MHT) are more than twice as likely than non-users to develop lower gastrointestinal bleeding and ischemic colitis, especially if they use the therapy for longer durations, according to a study at Digestive Disease Week 2015.

19 May 2015

Endo Pharmaceuticals supports efforts to bring first ever treatment guidelines for Peyronie's Disease

Endo Pharmaceuticals Inc., a subsidiary of Endo International plc, supports efforts to bring the medical community the first ever treatment guidelines for Peyronie's Disease (PD), a condition in which collagen plaque, or scar tissue, develops on the shaft of the penis, and may harden and reduce flexibility.

19 May 2015

Two-drug combination improves lung function in some cystic fibrosis patients

The combination of two drugs — an investigational drug used in conjunction with an already FDA-approved medication — improved lung function in patients with one form of cystic fibrosis, according to two new studies.

19 May 2015

BioNTech, Genmab to jointly develop and commercialize immunomodulatory antibodies for cancer

BioNTech AG, a fully integrated biotechnology company developing truly personalized cancer immunotherapies, announces that it has signed an agreement with Genmab A/S to jointly research, develop and commercialize multiple bispecific antibodies for cancer immunotherapy using proprietary technologies from both companies: BioNTech's proprietary immunomodulatory antibodies and Genmab's DuoBody technology platform.

19 May 2015

New study reveals that 'imperfect drug penetration' can accelerate pathogens' resistance

Prescribing patients two or more drugs that do not reach the same parts of the body could accelerate a pathogen's resistance to all of the drugs being used in treatment, according to a new study published today in the Proceedings of the National Academy of Sciences.

19 May 2015

Blood-thinning treatment safe for patients with brain metastases

Cancer patients with brain metastases who develop blood clots may safely receive blood thinners without increased risk of dangerous bleeding, according to a study, published online today in Blood, the Journal of the American Society of Hematology.

19 May 2015

OSU researchers find promising approach to treating epithelial cancer

Researchers at Oregon State University are pursuing a new concept in treatment of epithelial cancer, especially head and neck cancer, by using two promising "analogs" of an old compound that was once studied as a potent anti-tumor agent, but long ago abandoned because it was too toxic.

19 May 2015

Monash University-led researchers call for HCV patients to gain improved access to effective drugs

In a letter to the Medical Journal of Australia published today, a Monash University-led team is asking for hepatitis C virus patients to gain improved access to drugs to prevent liver related deaths.

19 May 2015

Pharmaceutical News

ICS use may lower risk of mortality from pneumonia and other causes in COPD patients

Canada lagging behind similar OECD countries with regard to public drug plan reimbursement

FDA accepts Tris Pharma's Dyanavel XR NDA for review

Enterprise Therapeutics secures additional funding to accelerate drug discovery for treatment of respiratory diseases

Second-generation antibiotic shows promise against common bacterial infections

HQO report shows variations across Ontario's long-term care homes regarding antipsychotic drug use

New data shows safety and efficacy of biosimilar infliximab treatment in IBD patients

Omega-3 fatty acids improve cognitive flexibility in older adults at risk of late-onset Alzheimer's disease

New UCLA study finds Naltrexone drug as promising treatment for methamphetamine addiction

Twin Cities Orthopedics joins Deterra partnership program to reduce prescription drug abuse and misuse

Short course of oral steroids unlikely to provide much benefit for patients with acute sciatica

Lakewood-Amedex's novel class of antimicrobials prove effective at killing MDR-TB strains

Current menopausal hormone therapy users at increased risk of experiencing GI bleeding

Endo Pharmaceuticals supports efforts to bring first ever treatment guidelines for Peyronie's Disease

Two-drug combination improves lung function in some cystic fibrosis patients

BioNTech, Genmab to jointly develop and commercialize immunomodulatory antibodies for cancer

New study reveals that 'imperfect drug penetration' can accelerate pathogens' resistance

Blood-thinning treatment safe for patients with brain metastases

OSU researchers find promising approach to treating epithelial cancer

Monash University-led researchers call for HCV patients to gain improved access to effective drugs

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