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New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

Individuals with type 2 diabetes, who are resistant to insulin, have an excess blood glucose level, which they are now trying to reduce using a new class of diabetes drugs known as the gliflozins.

22 Apr 2015

Astellas, Potenza collaborate to develop immuno-oncology therapeutics for patients with certain cancers

Astellas Pharma Inc. and Potenza Therapeutics, Inc., a biotechnology company developing a portfolio of immuno-oncology programs, today announced an exclusive research and development collaboration.

22 Apr 2015

Cantrixil drug granted FDA Orphan Drug Designation for treatment of ovarian cancer

US-Australian drug discovery company, Novogen, today announced that its subsidiary joint venture company with Yale University, CanTx, Inc, has today received notification from the U.S. Food and Drug Administration that its chemotherapy candidate drug, Cantrixil, has been granted Orphan Drug Designation for ovarian cancer.

22 Apr 2015

Study explores artemisinin resistance in Plasmodium falciparum malaria

According to the World Health Organization's 2014 World Malaria Report, there are an estimated 198 million cases of malaria worldwide with 3.3 billion people at risk for contracting the infection. Although the impact of malaria is still significant, the statistics reflect a considerable reduction in the global malaria burden. Since 2010, disease transmission has been reduced by 30 percent and mortality due to malaria has decreased by almost half.

21 Apr 2015

Lab-on-paper technique could help detect low quality antimalarial drugs

Access to high-quality medicine is a basic human right, but over four billion people live in countries where many medications are substandard or fake. Marya Lieberman of the Department of Chemistry and Biochemistry at the University of Notre Dame and Abigail Weaver a postdoctoral associate in the University's Department of Civil Engineering and Environmental and Earth Sciences took up the challenge of how people in developing countries could detect low quality antimalarial drugs without expensive equipment and without handling dangerous chemicals.

21 Apr 2015

Boehringer Ingelheim seeks FDA approval for Pradaxa to treat DVT and PE

Legal-Bay LLC, The Lawsuit Settlement Funding Company, announced today that Pradaxa's maker, Boehringer Ingelheim Pharmaceuticals, is seeking FDA approval for its blood thinner to treat DVT and PE.

21 Apr 2015

New combination therapy could overcome treatment resistance, relapse in breast cancer

Researchers from The University of Manchester working with drug development company Evgen Pharma, have developed a new combination of drugs which could overcome treatment resistance and relapse in breast cancer.

21 Apr 2015

New mathematical model to predict pharmacodynamic activity may help improve drug discovery

A new mathematical model that uses drug-target kinetics to predict how drugs work in vivo may provide a foundation to improve drug discovery, which is frequently hampered by the inability to predict effective doses of drugs.

21 Apr 2015

UC San Diego study examines counterfeit drug penetration in global medicine supply chains

When you take a medication for, say, high cholesterol, do you know that pill is really what the label says it is? Depending upon the type of medicine and where you live, the threat of falsified medications (also referred to as counterfeit, fraudulent, and substandard) can be quite real, yet the full scope and prevalence of the problem is poorly understood, say researchers at University of California, San Diego School of Medicine in a new report published April 20 in the American Journal of Tropical Medicine and Hygiene.

21 Apr 2015

Study: Extending natalizumab treatment effective in preventing MS symptoms

In a study of 1,964 patients with multiple sclerosis (MS) led by researchers at the NYU Langone Multiple Sclerosis Comprehensive Care Center, extending the dose of natalizumab from 4 weeks up to 8 weeks was shown to be well-tolerated and effective in patients, and resulted in no cases of the potentially fatal side effect progressive multifocal leukoencephalopathy (PML).

21 Apr 2015

Two existing drugs may reverse damage caused by multiple sclerosis

A pair of topical medicines already alleviating skin conditions each may prove to have another, even more compelling use: instructing stem cells in the brain to reverse damage caused by multiple sclerosis.

21 Apr 2015

Designing AR Inhibitors Team wins AACR Team Science Award for developing prostate cancer treatment

The American Association for Cancer Research will award the ninth annual AACR Team Science Award to the Designing Androgen Receptor (AR) Inhibitors Team from Memorial Sloan Kettering Cancer Center and the University of California, Los Angeles at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.

21 Apr 2015

Mott poll measures public's views about use of medical marijuana for children

Medical marijuana and children don't mix, most Americans say. While nearly two-thirds of people agree that their state should allow medical marijuana for adults, half as many - just over a third - say it should be allowed for children, according to today's University of Michigan C.S. Mott Children's Hospital National Poll on Children's Health that included a national sample of adults in the U.S.

21 Apr 2015

New UM SOM study reveals why thiazide drugs not effective in some patients

Every year, more than 120 million prescriptions are written worldwide for thiazide drugs, a group of salt-lowering medicines used to treat high blood pressure. These drugs are often work very well, and over decades have saved hundreds of thousands of lives.

21 Apr 2015

Two existing drugs may potentially become new drug target for multiple sclerosis

Two drugs already on the market -- an antifungal and a steroid -- may potentially take on new roles as treatments for multiple sclerosis. According to a study published in Nature today, researchers discovered that these drugs may activate stem cells in the brain to stimulate myelin producing cells and repair white matter, which is damaged in multiple sclerosis.

20 Apr 2015

Ibrutinib (IMBRUVICA) may be effective for pancreatic ductal adenocarcinoma

Ibrutinib (IMBRUVICA) data presented yesterday by Pharmacyclics, Inc. at the American Association for Cancer Research Annual Meeting suggest that ibrutinib may be an effective therapeutic option for pancreatic ductal adenocarcinoma (PDAC), as shown in both a transgenic mouse model and an in-vivo model of patient-derived xenograft (PDX) mice (grafts of tissue taken from a pancreatic cancer patient and grafted into a mouse).

20 Apr 2015

Lupin introduces first Brand product Zaxine in Canada

Pharma Major Lupin Limited announced today that its Canadian subsidiary, Lupin Pharma Canada Limited (collectively Lupin) has launched its first Brand product Zaxine under a strategic licensing agreement with the North Carolina based GI specialty company Salix Pharmaceuticals Inc.

20 Apr 2015

Can-Fite seeks EMA Orphan Drug Designation for CF102 in HCC

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that are being developed to treat inflammatory diseases, cancer and sexual dysfunction, announced today it has submitted an application to the European Medicines Agency for Orphan Drug Designation for its drug candidate CF102 in the treatment of hepatocellular carcinoma (HCC), the most common form of liver cancer.

20 Apr 2015

Pembrolizumab drug halts tumor growth in 76% of patients with pleural mesothelioma

The PD-1 inhibitor pembrolizumab, a cancer immunotherapy drug, shrank or halted growth of tumors in 76 percent of patients with pleural mesothelioma, a rare and deadly form of cancer that arises in the outer lining of the lungs and internal chest wall, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

20 Apr 2015

Malaria parasites with Ap2mu gene mutation less sensitive to antimalarial drug artemisinin

Early indicators of the malaria parasite in Africa developing resistance to the most effective drug available have been confirmed, according to new research published in Antimicrobial Agents and Chemotherapy.

20 Apr 2015

Pharmaceutical News

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

Astellas, Potenza collaborate to develop immuno-oncology therapeutics for patients with certain cancers

Cantrixil drug granted FDA Orphan Drug Designation for treatment of ovarian cancer

Study explores artemisinin resistance in Plasmodium falciparum malaria

Lab-on-paper technique could help detect low quality antimalarial drugs

Boehringer Ingelheim seeks FDA approval for Pradaxa to treat DVT and PE

New combination therapy could overcome treatment resistance, relapse in breast cancer

New mathematical model to predict pharmacodynamic activity may help improve drug discovery

UC San Diego study examines counterfeit drug penetration in global medicine supply chains

Study: Extending natalizumab treatment effective in preventing MS symptoms

Two existing drugs may reverse damage caused by multiple sclerosis

Designing AR Inhibitors Team wins AACR Team Science Award for developing prostate cancer treatment

Mott poll measures public's views about use of medical marijuana for children

New UM SOM study reveals why thiazide drugs not effective in some patients

Two existing drugs may potentially become new drug target for multiple sclerosis

Ibrutinib (IMBRUVICA) may be effective for pancreatic ductal adenocarcinoma

Lupin introduces first Brand product Zaxine in Canada

Can-Fite seeks EMA Orphan Drug Designation for CF102 in HCC

Pembrolizumab drug halts tumor growth in 76% of patients with pleural mesothelioma

Malaria parasites with Ap2mu gene mutation less sensitive to antimalarial drug artemisinin

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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