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Sildenafil drug may effectively relieve nerve damage in men with long-term diabetes

New animal studies at Henry Ford Hospital found that sildenafil, a drug commonly used to treat erectile dysfunction, may be effective in relieving painful and potentially life-threatening nerve damage in men with long-term diabetes.

18 Mar 2015

Simultaneous use of hormones and statins can protect women from heart disease after menopause

Hormones may not protect women from heart disease or stroke after menopause, but when combined with cholesterol-lowering statin drugs, they may help protect women from these killers, shows a population study from Sweden to be published in the April issue of Menopause, the journal of The North American Menopause Society.

18 Mar 2015

Anesthetics interfere with certain proteins in excitatory neurons that transmit signals

Anesthetics have been used in surgical procedures for more than 150 years, but the mechanisms by which inhaled anesthesia actually work are poorly understood. Now, researchers at Johns Hopkins Medicine have discovered that anesthetics bind to and interfere with certain proteins in excitatory neurons, which are necessary for these neurons to transmit signals involved in anesthesia and the perception of pain.

18 Mar 2015

Improving adherence to ulcerative colitis medications: an interview with Mattias Norrman, COO, Tillotts Pharma

The objective of the survey was two-sided. On one side, we wanted to better understand needs, concerns and attitudes of people with UC in an effort to identify solutions to improve the management of the disease. On the other, we wanted to build a questionnaire that could be used by HCPs to help define patients’ needs and concerns.

17 Mar 2015

Global breast cancer therapeutics market estimated to reach $13.38 billion in 2018

Despite the availability of approximately 25 drugs for the treatment of breast cancer, the unmet need in the global market is vast. To address this drawback, pharmaceutical companies have established a robust pipeline that currently has about 52 drugs in development. While chemotherapy remains the most important class of drugs for breast cancer treatment, the trend toward targeted drugs is on the rise.

17 Mar 2015

Active ingredient dextromethorphan may help people with Type 2 diabetes

The active ingredient dextromethorphan, which is contained in many over-the-counter cough remedies, has been shown to improve blood sugar levels in type 2 diabetes (diabetes mellitus). That was the finding of a recent international study, in which the Center for Physiology and Pharmacology of MedUni Vienna played a significant part and which has now been published in the leading medical journal "Nature Medicine".

17 Mar 2015

Study: Cancer drug may help reduce bleeding in HHT patients

A cancer drug that helps keep tumors from growing blood vessels may help patients with a rare genetic condition in which malformed vessels increase their risk for bleeding and anemia.

17 Mar 2015

Ludwig researchers establish proof of concept for new approach to drug design

Exploring the fundamental mechanism by which a cell-surface receptor transmits its signal, an international team of Ludwig researchers and their colleagues has established proof of concept for an entirely new approach to drug design. They report that a class of synthetic molecules known as diabodies can, from outside the cell, latch onto a target receptor and manipulate it in such a manner as to induce distinct and varying effects within cells and tissues.

17 Mar 2015

New hepatitis C drugs to place economic burden on health care system, predicts MD Anderson study

The cost of treating people infected with the hepatitis C virus (HCV) with newly approved therapies will likely place a tremendous economic burden on the country's health care system. The prediction comes from a cost-effectiveness analysis led by researchers at The University of Texas MD Anderson Cancer Center.

17 Mar 2015

Sugar-lowering medications prescribed to diabetic patients may increase heart failure risk

A comprehensive study examining clinical trials of more than 95,000 patients has found that glucose or sugar-lowering medications prescribed to patients with diabetes may pose an increased risk for the development of heart failure in these patients.

17 Mar 2015

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

NantWorks, Inc. and Sorrento Therapeutics, Inc., announced today that they have entered into a binding agreement to initiate a global collaboration to discover and develop novel anti-cancer immunotherapies derived from Sorrento's proprietary G-MAB library against neoepitopes of tumor-specific antigens discovered using NantWorks' proprietary pan-omics based, precision medicine approach.

16 Mar 2015

Vaxil Bio's ImMucin receives EMA orphan drug designation for treatment of Multiple Myeloma

Vaxil Bio, a leading developer of immunotherapeutic products to treat cancer and infectious diseases, reports today that its lead drug candidate, ImMucin has received orphan drug designation from the European Medicines Agency of the European Commission for the treatment of Multiple Myeloma (MM), a blood cancer.

16 Mar 2015

Endo announces commercial availability of NATESTO nasal gel for men with hypogonadism

Endo Pharmaceuticals Inc., a subsidiary of Endo International plc (NASDAQ: ENDP) (TSX: ENL), announced today the commercial availability of NATESTO (testosterone nasal gel), the first and only nasal gel for testosterone replacement therapy in adult males diagnosed with hypogonadism.

16 Mar 2015

Meta-analysis finds that high dose zinc acetate lozenges may help reduce duration of cold symptoms

According to a meta-analysis published in BMC Family Practice, high dose zinc acetate lozenges shortened the duration of common-cold associated nasal discharge by 34%, nasal congestion by 37%, scratchy throat by 33%, and cough by 46%.

16 Mar 2015

Cannabis use increases manic, depressive symptoms

The first study to examine the use of cannabis in the context of daily life among people with Bipolar Disorder has shown how the drug is linked to increases in both manic and depressive symptoms.

16 Mar 2015

Common herpes drug Valacyclovir decreases HIV-1 levels

Case Western Reserve researchers are part of an international team that has discovered that a common herpes drug reduces HIV-1 levels — even when patients do not have herpes.

16 Mar 2015

Potential solutions to help reduce high cost of cancer drugs in the U.S.

Increasingly high prices for cancer drugs are affecting patient care in the U.S. and the American health care system overall, say the authors of a special article published online in the journal Mayo Clinic Proceedings.

16 Mar 2015

Flu vaccine based upon four strains of inactivated influenza enhances flu protection

A flu vaccine given just under the surface of the skin that includes four strains of inactivated influenza could be more protective than a similar flu vaccine containing only three strains, Saint Louis University research found.

16 Mar 2015

Researchers investigate effects of neuromodulatory medication on orofacial tissue

Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher M.J. Al-Musawi, Newcastle University, Newcastle upon Tyne, UK, will present a study titled "In Vitro Effects of Topical Neuromodulatory Medication on Orofacial Tissue."

13 Mar 2015

Study compares HA injections and triamcinolone in improving pain in patients with lumbar ZJT arthropathy

A study presented at AAP 2015 San Antonio compares the effectiveness of HA injections to triamcinolone in improving pain and function in patients with lumbar ZJT arthropathy.

13 Mar 2015

Pharmaceutical News

Sildenafil drug may effectively relieve nerve damage in men with long-term diabetes

Simultaneous use of hormones and statins can protect women from heart disease after menopause

Anesthetics interfere with certain proteins in excitatory neurons that transmit signals

Improving adherence to ulcerative colitis medications: an interview with Mattias Norrman, COO, Tillotts Pharma

Global breast cancer therapeutics market estimated to reach $13.38 billion in 2018

Active ingredient dextromethorphan may help people with Type 2 diabetes

Study: Cancer drug may help reduce bleeding in HHT patients

Ludwig researchers establish proof of concept for new approach to drug design

New hepatitis C drugs to place economic burden on health care system, predicts MD Anderson study

Sugar-lowering medications prescribed to diabetic patients may increase heart failure risk

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

Vaxil Bio's ImMucin receives EMA orphan drug designation for treatment of Multiple Myeloma

Endo announces commercial availability of NATESTO nasal gel for men with hypogonadism

Meta-analysis finds that high dose zinc acetate lozenges may help reduce duration of cold symptoms

Cannabis use increases manic, depressive symptoms

Common herpes drug Valacyclovir decreases HIV-1 levels

Potential solutions to help reduce high cost of cancer drugs in the U.S.

Flu vaccine based upon four strains of inactivated influenza enhances flu protection

Researchers investigate effects of neuromodulatory medication on orofacial tissue

Study compares HA injections and triamcinolone in improving pain in patients with lumbar ZJT arthropathy

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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