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CureVac collaborates with Janssen on development of influenza vaccine based on mRNA

CureVac, a clinical stage biopharmaceutical company that has pioneered the development of a new class of therapies and vaccines based on messenger RNA (mRNA), today announced that it has entered into a collaboration and licensing agreement with Janssen Pharmaceuticals, Inc. Under the agreement CureVac will collaborate with Crucell Holland B.V. (a member of the Janssen Pharmaceutical Companies) on the development of an influenza vaccine based on CureVac's RNActive® technology.

3 Oct 2013

Scientists identify new drug for inherited form of cancer with no known cure

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a new drug candidate for an inherited form of cancer with no known cure.

3 Oct 2013

New method to monitor activity of gene promoters during response to drug

When developing new drugs, monitoring cellular responses to candidate compounds is essential for assessing their efficacy and safety. Researchers from the RIKEN Center for Life Science Technologies report a new method to monitor and quantify the activity of gene promoters during the response to a drug, using the advanced gene expression analysis method CAGE followed by single-molecule sequencing.

3 Oct 2013

Researchers to develop nerve agent antidotes that can be used during chemical warfare

Ever since World War II, nerve agents have been a concern in modern warfare and up until now, the only antidotes available acted after the agents damaged the nervous system.

3 Oct 2013

NCI explores how erectile dysfunction drugs work to prevent colon cancer

Erectile dysfunction drugs may be able to help prevent or even treat colon cancer, researchers say.

3 Oct 2013

Sun Pharma, Intrexon Team Up To Target Ocular Diseases

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2 Oct 2013

Antimicrobial usage causes vancomycin-resistant enterococci outbreaks in Greek NICU

Administration of antibiotics may have caused successive outbreaks of vancomycin-resistant enterococci in a Greek neonatal intensive care unit, according to a study in the October issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology.

2 Oct 2013

Over-the-counter ibuprofen appears to be safest alternative for reducing post-operative pain

You may be able to eat all of the ice cream you want after having your tonsils removed, but researchers at Henry Ford Hospital in Detroit say you don't necessarily need a prescription to reduce post-operative pain -- an over-the-counter pain-reliever is just as effective.

2 Oct 2013

Genetic discovery could take guesswork out of prescribing correct dose of drugs

The discovery of genetic differences affecting up to a third of the population could take the guesswork out of prescribing the correct dose of 25 percent of drugs currently on the market, researchers say.

2 Oct 2013

Statin medications pose no threat to short-term memory and may protect against dementia

A review of dozens of studies on the use of statin medications to prevent heart attacks shows that the commonly prescribed drugs pose no threat to short-term memory, and that they may even protect against dementia when taken for more than one year.

2 Oct 2013

Remote stroke service increases rate of tPA therapy at community hospitals

A telestroke service increases the rate of effective tissue plasminogen activator therapy for patients with acute ischemic stroke treated at community hospitals, according to a report in the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

2 Oct 2013

FDA grants accelerated approval of Perjeta for people with HER2-positive early stage breast cancer

The U.S. Food and Drug Administration granted accelerated approval of a Perjeta- (pertuzumab) regimen for neoadjuvant treatment (use before surgery) in people with high-risk, HER2-positive early stage breast cancer.

2 Oct 2013

Study assess use of prescription painkillers for chronic pain among patients pre- and post-obesity surgery

Chronic use of prescription painkillers, also known as opioids, among obese patients prior to bariatric surgery continues after surgery, according to a new Kaiser Permanente study published today in the Journal of the American Medical Association.

2 Oct 2013

Researchers compare cardiovascular safety of two commonly used oral estrogen medications

The oral hormone therapy conjugated equine estrogens, which is used by women to relieve menopause symptoms, appears to be associated with increased risk for venous thrombosis (VT, blood clots) and possibly myocardial infarction (heart attack), but not ischemic stroke risk, when compared with the hormone therapy oral estradiol, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

1 Oct 2013

Life-prolonging effect of vitamin niacin demonstrated in roundworms

Who would not want to live a long and healthy life? A freely available food supplement could help in this respect, scientists from ETH Zurich have demonstrated in roundworms. Vitamin B3 - also known as niacin - and its metabolite nicotinamide in the worms' diet caused them to live for about one tenth longer than usual.

1 Oct 2013

Sun Pharma, Intrexon Team Up To Target Ocular Diseases

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1 Oct 2013

Validation of thrombin generation assay (TGA) for an IVIG drug announced by Haemtech Biopharma Services

Haemtech Biopharma Services (HBS) is pleased to announce the successful validation of a thrombin generation assay (TGA) for an IVIG drug. The assay was validated in 2012 to support the use of TGA as a release assay for Biotest Pharmaceuticals Corporation's U.S. Food and Drug Administration Biologics License Application for BIVIGAM® [Immune Globulin Intravenous (Human), 10% Liquid] product. The validated TGA assay was designed and performed on the Calibrated Automated Thrombogram® platform (CAT) from Diagnostica Stago, Inc. (Parsippany, NJ).

1 Oct 2013

New approaches needed for testing cancer drugs

Research institutes, regulators and the pharmaceutical industry are urged to cooperate to develop new approaches to testing cancer drugs, in order to bring the revolution in personalised medicine to patients across Europe, says the European Society for Medical Oncology.

1 Oct 2013

FDA grants accelerated approval to Perjeta for neoadjuvant treatment of breast cancer

The U.S. Food and Drug Administration today granted accelerated approval to Perjeta (pertuzumab) as part of a complete treatment regimen for patients with early stage breast cancer before surgery (neoadjuvant setting). Perjeta is the first FDA-approved drug for the neoadjuvant treatment of breast cancer.

1 Oct 2013

Researchers discover how aspirin improves survival in patients diagnosed with colon cancer

Researchers believe they have discovered how aspirin improves survival in patients diagnosed with colon cancer, the 2013 European Cancer Congress (ECC2013) heard today.

1 Oct 2013

Pharmaceutical News

CureVac collaborates with Janssen on development of influenza vaccine based on mRNA

Scientists identify new drug for inherited form of cancer with no known cure

New method to monitor activity of gene promoters during response to drug

Researchers to develop nerve agent antidotes that can be used during chemical warfare

NCI explores how erectile dysfunction drugs work to prevent colon cancer

Sun Pharma, Intrexon Team Up To Target Ocular Diseases

Antimicrobial usage causes vancomycin-resistant enterococci outbreaks in Greek NICU

Over-the-counter ibuprofen appears to be safest alternative for reducing post-operative pain

Genetic discovery could take guesswork out of prescribing correct dose of drugs

Statin medications pose no threat to short-term memory and may protect against dementia

Remote stroke service increases rate of tPA therapy at community hospitals

FDA grants accelerated approval of Perjeta for people with HER2-positive early stage breast cancer

Study assess use of prescription painkillers for chronic pain among patients pre- and post-obesity surgery

Researchers compare cardiovascular safety of two commonly used oral estrogen medications

Life-prolonging effect of vitamin niacin demonstrated in roundworms

Sun Pharma, Intrexon Team Up To Target Ocular Diseases

Validation of thrombin generation assay (TGA) for an IVIG drug announced by Haemtech Biopharma Services

New approaches needed for testing cancer drugs

FDA grants accelerated approval to Perjeta for neoadjuvant treatment of breast cancer

Researchers discover how aspirin improves survival in patients diagnosed with colon cancer

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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