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Wistar Institute receives $1.5M grant to prepare potential new prostate cancer drug for clinical use

To prepare a potential new prostate cancer drug, called Gamitrinib, for trial in humans, The Wistar Institute has received a $1.5 million grant from the US Department of Defense's Congressionally Directed Medical Research Program.

13 Sep 2013

Helper T cells important for AIDS vaccine development

A major new finding that will significantly advance efforts to create the world's first antibody-based AIDS vaccine was published today by researchers from the La Jolla Institute for Allergy and Immunology.

13 Sep 2013

Researchers potentially reached milestone in vaccine treatment for genital herpes

Sexually transmitted infection researchers potentially have reached a milestone in vaccine treatment for genital herpes, according to a report to be presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy in Denver, Colo., on today, Sept. 12.

13 Sep 2013

Microbiologist finds breakthrough herbal medicine treatment for common human fungal pathogen

A Kansas State University microbiologist has found a breakthrough herbal medicine treatment for a common human fungal pathogen that lives in almost 80 percent of people.

13 Sep 2013

Botox Cosmetic receives FDA approval for treatment of crow’s feet lines

The U.S. Food and Drug Administration today approved a new use for Botox Cosmetic (onabotulinumtoxinA) for the temporary improvement in the appearance of moderate to severe lateral canthal lines, known as crow’s feet, in adults. Botox Cosmetic is the only FDA approved drug treatment option for lateral canthal lines.

12 Sep 2013

Current criteria for ALK positive lung cancer needs to be redefined

A University of Colorado Cancer Center study published today in the journal Cancer shows that the current criteria used to match lung cancers with the drug crizotinib may miss some patients who could benefit from the drug. The findings suggest that doctors should look closer at borderline or atypical ALK-negative cases, and could widen the population of lung cancer patients offered treatment with crizotinib or other ALK-inhibitor drugs.

12 Sep 2013

arGEN-X generates potent antibody antagonists of Nav1.7 using SIMPLE Antibody technology

arGEN-X, a clinical stage human monoclonal antibody therapeutics company, announces it has successfully generated potent antibody antagonists of Nav1.7, using its proprietary SIMPLE Antibody™ technology.

12 Sep 2013

Study finds low doses of vancomycin to be effective in treating serious C-difficile infection

Clostridium difficile infection (CDI) treatment in a hospital setting using low dose oral vancomycin showed similar effectiveness compared to high dose, according to a new study by researchers at Montefiore Medical Center and Albert Einstein College of Medicine of Yeshiva University.

12 Sep 2013

New HIV/AIDS vaccine candidate appears to clear AIDS-causing virus from body

An HIV/AIDS vaccine candidate developed by researchers at Oregon Health & Science University appears to have the ability to completely clear an AIDS-causing virus from the body.

12 Sep 2013

Study: Atorvastatin reduces inflammation, thrombogenesis in patients with acute ischemic stroke

The population of northeastern China has a high incidence of ischemic stroke. Previous studies have shown that intracranial large-artery atherosclerosis is one of the main causes of ischemic stroke, and that the mechanisms are related to inflammation and thrombosis of the affected arteries.

12 Sep 2013

Hydroxyurea treatment prevents complications, lowers medical care costs in children sickle cell disease

The benefits of hydroxyurea treatment in people with sickle cell disease are well known -- fewer painful episodes, fewer blood transfusions and fewer hospitalizations. Now new research from the Johns Hopkins Children's Center and other institutions reveals that by preventing such complications, the drug can also considerably lower the overall cost of medical care in children with this condition.

12 Sep 2013

CPT-F antibiotic drug may hold promise for treating potentially fatal MRSA pneumonia

A drug approved just two years ago for treating bacterial infections may hold promise for treating the potentially fatal MRSA pneumonia, according to a Henry Ford Hospital study.

12 Sep 2013

FDA grants Breakthrough Therapy designation to Syndax's entinostat for ER+ breast cancer

Syndax Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration has designated entinostat as a Breakthrough Therapy for the treatment of locally recurrent or metastatic estrogen receptor-positive (ER+) breast cancer when added to exemestane in postmenopausal women whose disease has progressed following non-steroidal aromatase inhibitor therapy.

12 Sep 2013

Undervaccination results in increased risk for whooping cough in young children

Undervaccination – not receiving all recommended vaccinations or not being vaccinated according to the Advisory Committee on Immunization Practices schedule – results in an increased risk for whooping cough in children 3 to 36 months of age, according to a new Kaiser Permanente study.

12 Sep 2013

MicroBiome Therapeutics' NM504 eliminates diarrhea caused by metformin in type 2 diabetes patient

MicroBiome Therapeutics LLC, a biotechnology company developing pharmaceutical and medical food products that shift the human microbiome in specific ways for improved health, today reported publication of a case report suggesting a potentially important new application for its lead product, NM504. NM504 is in clinical development to promote healthy blood glucose levels and metabolic fitness in prediabetic and diabetic populations.

11 Sep 2013

Scientists use nanodiamonds to boost delivery of drug to leukemic cells

By binding multiple molecules of a common leukemia drug with nanodiamonds, scientists from the National University of Singapore (NUS) and University of California, Los Angeles (UCLA) managed to boost the delivery of the drug to leukemic cells and retain the drug within the cells to combat the cancer.

11 Sep 2013

Combination drug does not improve survival in patients with severe alcoholic hepatitis

Four weeks of treatment with a combination of the drug pentoxifylline and the corticosteroid prednisolone did not improve 6-month survival compared with prednisolone alone in 270 patients with severe alcoholic hepatitis, according to a study in the September 11 issue of JAMA.

11 Sep 2013

Large numbers of kidney disease patients inappropriately prescribed statins to lower cholesterol

A new analysis concludes that large numbers of patients in advanced stages of kidney disease are inappropriately being prescribed statins to lower their cholesterol - drugs that offer them no benefit and may increase other health risks such as diabetes, dementia or muscle pain.

11 Sep 2013

Safety labeling changes announced for extended-release and long-acting opioid analgesics

The U.S. Food and Drug Administration today announced class-wide safety labeling changes and new postmarket study requirements for all extended-release and long-acting opioid analgesics intended to treat pain.

11 Sep 2013

Interferon-alpha 2b and ribavirin treatment may be effective for MERS-CoV infection

Treatment with two common drugs reduced viral replication and lung damage when given to monkeys infected with the virus that causes Middle East Respiratory Syndrome. The condition is deadly pneumonia that has killed more than 100 people, primarily in the Middle East.

10 Sep 2013

Pharmaceutical News

Wistar Institute receives $1.5M grant to prepare potential new prostate cancer drug for clinical use

Helper T cells important for AIDS vaccine development

Researchers potentially reached milestone in vaccine treatment for genital herpes

Microbiologist finds breakthrough herbal medicine treatment for common human fungal pathogen

Botox Cosmetic receives FDA approval for treatment of crow’s feet lines

Current criteria for ALK positive lung cancer needs to be redefined

arGEN-X generates potent antibody antagonists of Nav1.7 using SIMPLE Antibody technology

Study finds low doses of vancomycin to be effective in treating serious C-difficile infection

New HIV/AIDS vaccine candidate appears to clear AIDS-causing virus from body

Study: Atorvastatin reduces inflammation, thrombogenesis in patients with acute ischemic stroke

Hydroxyurea treatment prevents complications, lowers medical care costs in children sickle cell disease

CPT-F antibiotic drug may hold promise for treating potentially fatal MRSA pneumonia

FDA grants Breakthrough Therapy designation to Syndax's entinostat for ER+ breast cancer

Undervaccination results in increased risk for whooping cough in young children

MicroBiome Therapeutics' NM504 eliminates diarrhea caused by metformin in type 2 diabetes patient

Scientists use nanodiamonds to boost delivery of drug to leukemic cells

Combination drug does not improve survival in patients with severe alcoholic hepatitis

Large numbers of kidney disease patients inappropriately prescribed statins to lower cholesterol

Safety labeling changes announced for extended-release and long-acting opioid analgesics

Interferon-alpha 2b and ribavirin treatment may be effective for MERS-CoV infection

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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