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Use of anticoagulant does not reduce ischemic events among patients undergoing PCI

Use of the novel anticoagulant otamixaban did not reduce ischemic events compared with unfractionated heparin plus eptifibatide but increased bleeding among patients with non-ST-segment elevation acute coronary syndromes undergoing a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), according to a study published by JAMA.

2 Sep 2013

Drug for children with sickle cell anemia reduces hospitalizations and treatment costs

A drug proven effective for treatment of adults and children with sickle cell anemia reduced hospitalizations and cut annual estimated medical costs by 21 percent for affected infants and toddlers, according to an analysis led by St. Jude Children's Research Hospital. The report appears today in the advance online edition of the journal Pediatrics.

2 Sep 2013

Pre-treatment with prasugrel increases risk of bleeding without reducing risk of ischemic events

In patients with non-ST-elevation acute coronary syndrome (NSTE- ACS), pre-treatment with the P2Y12 antagonist prasugrel prior to catheterization, significantly increases the risk of life-threatening bleeding without reducing the risk of major ischemic events, according to the results of the ACCOAST (A Comparison of Prasugrel at PCI or Time of Diagnosis of Non-ST Elevation Myocardial Infarction) trial.

2 Sep 2013

Reimbursement systems appear to impact on achievement of cholesterol lowering targets

Dr Gitt said: "There are wide variations between European countries in the achievement of LDL-cholesterol (LDL-C) targets. However the effect of different reimbursement systems on meeting the targets was unknown."

2 Sep 2013

Study finds that high potency statins can beat dementia

Dr Lin said: "Statins are widely used in the older population to reduce the risk of cardiovascular disease. But recent reports of statin-associated cognitive impairment have led the US Food and Drug Administration (FDA) to list statin-induced cognitive changes, especially for the older population, in its safety communications."

2 Sep 2013

Meta-analysis indicates protective effect of statins in preventing cataracts

Cataracts are the leading cause of visual impairment worldwide affecting more than 20 million people. Statins are among the most commonly prescribed medications. In the USA they are prescribed to 1 in 3 people over 45 years of age at a cost of $35 billion annually.

2 Sep 2013

Nanostructures made of DNA strands can encapsulate, release small-molecule drugs

Nanoscale "cages" made from strands of DNA can encapsulate small-molecule drugs and release them in response to a specific stimulus, McGill University researchers report in a new study.

2 Sep 2013

Researchers identify potential drug target to recover from jet lag, disruptions in circadian system

University of Notre Dame researchers, as part of a collaborative effort, have identified a protein that potentially could be a target for drugs that would help people recover faster from jet lag and better adjust their circadian rhythms during rotational shift work.

31 Aug 2013

New delivery system for combination of 2 FDA approved drugs to fight HIV

A University of Minnesota research team featuring researchers from the Institute for Molecular Virology, School of Dentistry and Center for Drug Design has developed a new delivery system for a combination of two FDA approved drugs that may serve as an effective treatment for the human immunodeficiency virus (HIV).

31 Aug 2013

Study describes lack of positive effects in drugs, long-term data and robust direct comparisons in RA

The German Institute for Quality and Efficiency in Health Care (IQWiG) examined 9 biotechnologically produced drugs for the treatment of adults with rheumatoid arthritis in whom prior pharmacological treatment had failed.

31 Aug 2013

New angle for developing drugs to prevent thrombosis and heart attack

Platelets, which allow blood to clot, are at the heart of numerous cardiovascular problems, including heart attacks and stroke. New research has uncovered a key platelet protein that could offer a new angle for developing drugs to prevent thrombosis, or dangerous blood clots, in patients who are at high risk such as those with atherosclerosis or a history of heart problems.

31 Aug 2013

European Commission approves Stivarga tablets for treatment of patients with mCRC

Bayer HealthCare and Onyx Pharmaceuticals, Inc. (NASDAQ: ONXX) announced today that the European Commission has approved Stivarga® (regorafenib) tablets for the treatment of adult patients with metastatic colorectal cancer (mCRC).

30 Aug 2013

Statins offer great potential as anti-aging therapy

Not only do statins extend lives by lowering cholesterol levels and reducing the risks of cardiovascular disease, but new research in the September 2013 issue of The FASEB Journal suggests that they may extend lifespans as well. Specifically, statins may reduce the rate at which telomeres shorten, a key factor in the natural aging process. This opens the door for using statins, or derivatives of statins, as an anti-aging therapy.

30 Aug 2013

Longer looks: Lack of cancer vaccines, misleading nutrition labels, should women pay more than men for insurance?

Six years from now, when my daughter turns 11, she will get a three-part human papillomavirus vaccine that will reduce her chances of getting cervical cancer by around 70 percent.

30 Aug 2013

Findings lead to new drugs that block cancers from spreading to bone

When a cancer cell sloughs off the edge of a tumor in the breast, it faces a tough road to survive. The cell must not only remain physically intact as it rushes through blood vessels, but it also must find a new organ to lodge itself in, take in enough nutrients and oxygen to stay alive, and begin dividing, all while escaping notice by the body's immune system.

30 Aug 2013

BP and headache drug effectively speeds up treatment of TB

Infectious disease experts at Johns Hopkins have found, in studies in mice, that a drug better known as a treatment for high blood pressure and headaches effectively speeds up treatment of TB when added to the standard, daily antibiotic regimen. Test animals were cured in four months instead of the usual six.

30 Aug 2013

Targeted Medical Pharma launches new division to manufacture and distribution dietary supplements

Targeted Medical Pharma, Inc., a biotechnology company that develops and distributes prescription medical foods to physicians and pharmacies, today announced the launch of a new division that will specialize in the manufacturing and distribution of a proprietary line of dietary supplements.

30 Aug 2013

JCVI Receives $1.25M For Healthy Aging Study

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29 Aug 2013

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

A new clinical study at the University of Michigan Health System will test the ability of a once daily dose of doxycycline to reduce the growth of small abdominal aortic aneurysms.

29 Aug 2013

Researchers discover old cancer drug can be used to prevent rejection of transplanted tissue

Researchers at Lund University have unexpectedly discovered that an old cancer drug can be used to prevent rejection of transplanted tissue. The researchers now have high hopes that their discovery could lead to new treatments for both transplant patients and patients with autoimmune diseases.

29 Aug 2013

Pharmaceutical News

Use of anticoagulant does not reduce ischemic events among patients undergoing PCI

Drug for children with sickle cell anemia reduces hospitalizations and treatment costs

Pre-treatment with prasugrel increases risk of bleeding without reducing risk of ischemic events

Reimbursement systems appear to impact on achievement of cholesterol lowering targets

Study finds that high potency statins can beat dementia

Meta-analysis indicates protective effect of statins in preventing cataracts

Nanostructures made of DNA strands can encapsulate, release small-molecule drugs

Researchers identify potential drug target to recover from jet lag, disruptions in circadian system

New delivery system for combination of 2 FDA approved drugs to fight HIV

Study describes lack of positive effects in drugs, long-term data and robust direct comparisons in RA

New angle for developing drugs to prevent thrombosis and heart attack

European Commission approves Stivarga tablets for treatment of patients with mCRC

Statins offer great potential as anti-aging therapy

Longer looks: Lack of cancer vaccines, misleading nutrition labels, should women pay more than men for insurance?

Findings lead to new drugs that block cancers from spreading to bone

BP and headache drug effectively speeds up treatment of TB

Targeted Medical Pharma launches new division to manufacture and distribution dietary supplements

JCVI Receives $1.25M For Healthy Aging Study

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

Researchers discover old cancer drug can be used to prevent rejection of transplanted tissue

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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