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Whitehead Institute researchers identify drug target for anemia

Researchers at Whitehead Institute have identified a protein that is the target of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy.

10 Jun 2013

FDA panel loosens Avandia safety restrictions

Despite some concern over whether the diabetes drug Avandia can increase heart problems, an FDA panel Thursday loosened restrictions on how doctors can prescribe the drug.

10 Jun 2013

Drug regulators slow to pursue concerns about potential adverse effects of new diabetes drugs

The BMJ and Channel 4 Dispatches investigated and found that evidence suggesting potential harm from the drugs in industry studies has not been published.

10 Jun 2013

Available drugs may have a dramatic impact on children stricken with Tay-Sachs disease

A team of researchers has made a significant discovery which may have a dramatic impact on children stricken with Tay-Sachs disease, a degenerative and fatal neurological condition that often strikes in the early months of life.

7 Jun 2013

Ingenol mebutate drug does not offer added benefit over diclofenac/hyaluronic acid gel

The drug ingenol mebutate (trade name: Picato) has been approved in Germany since November 2012 as a gel for the treatment of certain forms of actinic keratosis in adults. In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG) the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this new drug offers an added benefit over diclofenac/hyaluronic acid gel. Such an added benefit cannot be derived from the dossier, however, as the drug manufacturer did not submit any relevant data: it did not cite any studies that directly compared ingenol mebutate with diclofenac/hyaluronic acid gel, and the method chosen by the manufacturer for an indirect comparison was unsuitable.

7 Jun 2013

Aflibercept drug used for AMD shows no added benefit over current standard therapy

The drug aflibercept (trade name: Eylea) has been approved in Germany since November 2012 for the treatment of wet age-related macular degeneration (AMD). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG) the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this new drug offers an added benefit over the current standard therapy.

7 Jun 2013

$Epidural steroid injection is associated with increased spinal fracture$

Epidural steroid injection is associated with increased spinal fracture

Most aging adults will experience back pain or a spinal disorder at some time in their life. In fact, about 25.8 million visits were made to physicians' offices due to primary back problems. Treatment focuses on pain relief and is available in both non-surgical (medication or physical therapy) and surgical forms.

7 Jun 2013

Faster, more potent antithrombotic drugs recommended for high-risk heart attack patients

The Cardiovascular Research Laboratory of the Bellvitge Biomedical Research Institute led by the cardiologist of the Bellvitge University Hospital Jos- Luis Ferreiro has conducted a study on the effect of antiplatelet drugs given to high risk patients suffering from acute myocardial infaction (heart attack) in the context of the Infarction Code.

6 Jun 2013

New technique for developing complex protein drugs from bacteria

A cheaper, more efficient technique for developing complex protein drugs from bacteria has been developed at the University of Sheffield.

6 Jun 2013

Solid formulations of the recombinant anthrax vaccine: an interview with Dr Mark Carnegie-Brown, CEO, Glide Pharma

Anthrax vaccines have a prominent place in the history of medicine. This goes back to, Pasteur, who while everybody associates with the milk treatment process, also worked on rabies and Anthrax vaccines in cattle.

6 Jun 2013

CytomX collaborates with Pfizer to develop, commercialize more effective antibody-drug conjugates

CytomX Therapeutics, Inc., a biotechnology company developing a new generation of targeted antibody therapeutics, today announced that it has entered into a global strategic collaboration with Pfizer Inc. to develop and commercialize multiple Probody-Drug Conjugates.

6 Jun 2013

Positive effect of aspirin on cancer mortality influences aspirin prescription for primary prevention in men

While aspirin has been shown to be effective in preventing heart attacks in men, it also increases the risk of gastrointestinal bleeding and possibly stroke, even at low doses. As such, national guidelines suggest that aspirin be used for prevention only in men at higher risk for cardiovascular events, so that the benefits of aspirin are greater than its adverse effects.

6 Jun 2013

Scientists suggest that Oprl1 receptor is altered in mice with PTSD-like symptoms

When injected into mice immediately following a traumatic event, a new drug prevents the animals from developing memory problems and increased anxiety that are indicative of post-traumatic stress disorder.

6 Jun 2013

EMRs emerge as valuable resource for detecting bad drug reactions

NJIT Assistant Professor Mei Liu, PhD, a computer scientist, has recently shown in a new study that electronic medical records can validate previously reported adverse drug reactions and report new ones.

6 Jun 2013

Scientists develop first dual-action drug against melanoma skin cancer cells

Scientists are reporting development and successful lab tests on the first potential drug to pack a lethal one-two punch against melanoma skin cancer cells. Hit number one destroys cells in the main tumor, and the second hit blocks the spread of the cancer to other sites in the body, according to their report in the journal ACS Chemical Biology.

6 Jun 2013

New research suggests that surgical anesthesia may also have lasting effects on adult brains

As pediatric specialists become increasingly aware that surgical anesthesia may have lasting effects on the developing brains of young children, new research suggests the threat may also apply to adult brains.

6 Jun 2013

Neutra's MMJ subsidiary forms joint venture to market, develop cannabis delivery systems

In a major step forward in its plans to deliver healthier, more effective innovations to the fast-growing medical marijuana industry in the U.S., Neutra Corp. announced today that its MMJ subsidiary, Cannabis Technologies, Inc., has formed a new joint venture with Field of View Technologies, LLC, to market and develop breakthrough cannabis delivery systems.

5 Jun 2013

Study: New genetic marker predicts warfarin dose in African-Americans

A newfound genetic marker promises to better predict warfarin dose in African-Americans, according to a study published online today in The Lancet. If confirmed in further studies, the finding may help to avert more of the bleeds and blood clots that come when a patient's starting dose misses the drug's narrow safety window.

5 Jun 2013

Low-dose ketamine anesthetic has potential to alleviate severe depression

Low-dose intravenous infusions of ketamine, a general anesthetic used in minor surgeries, given over a long period are an effective treatment for depression, Mayo Clinic researchers found. The study is published in the Journal of Psychopharmacology.

5 Jun 2013

Young adults reduce drug misuse if they are part of community-based prevention effort

Prevention is often the best medicine, not only for physical health, but also public health, according to researchers at Penn State and Iowa State University.

5 Jun 2013

Pharmaceutical News

Whitehead Institute researchers identify drug target for anemia

FDA panel loosens Avandia safety restrictions

Drug regulators slow to pursue concerns about potential adverse effects of new diabetes drugs

Available drugs may have a dramatic impact on children stricken with Tay-Sachs disease

Ingenol mebutate drug does not offer added benefit over diclofenac/hyaluronic acid gel

Aflibercept drug used for AMD shows no added benefit over current standard therapy

Epidural steroid injection is associated with increased spinal fracture

Faster, more potent antithrombotic drugs recommended for high-risk heart attack patients

New technique for developing complex protein drugs from bacteria

Solid formulations of the recombinant anthrax vaccine: an interview with Dr Mark Carnegie-Brown, CEO, Glide Pharma

CytomX collaborates with Pfizer to develop, commercialize more effective antibody-drug conjugates

Positive effect of aspirin on cancer mortality influences aspirin prescription for primary prevention in men

Scientists suggest that Oprl1 receptor is altered in mice with PTSD-like symptoms

EMRs emerge as valuable resource for detecting bad drug reactions

Scientists develop first dual-action drug against melanoma skin cancer cells

New research suggests that surgical anesthesia may also have lasting effects on adult brains

Neutra's MMJ subsidiary forms joint venture to market, develop cannabis delivery systems

Study: New genetic marker predicts warfarin dose in African-Americans

Low-dose ketamine anesthetic has potential to alleviate severe depression

Young adults reduce drug misuse if they are part of community-based prevention effort

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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