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New research shows effects of long-term use of opioid therapy

Half of patients on high-dose, long-term opioid therapy had hormonal disturbances or signs of inflammation, while 100 percent reported improved pain control and mental outlook, new research shows.

15 Apr 2013

U.S., Chinese researchers developing vaccine for H7N9 avian flu virus; Some question speed of case reporting

"Less than two weeks after Chinese officials released the genetic sequence of a new type of bird flu [H7N9], U.S. vaccine experts are well on the way to making a vaccine to protect people against it," NBC News's "Vitals" blog reports (Fox, 4/10).

12 Apr 2013

Nalmefene can provide important clinical benefit for alcohol-dependent patients

A potential new treatment for alcoholism called nalmefene is effective and safe for reducing alcohol consumption in alcohol dependent individuals, says a new study published this week in Biological Psychiatry.

12 Apr 2013

New process to create malaria drug artemisinin should provide stable supply, reduce cost, researchers report

"U.S. scientists on Wednesday said they had used baker's yeast to make a key ingredient of malaria drugs, a feat that could iron out fluctuations in supply caused by sourcing the chemical from a Chinese herb," Artemisia annua, Agence France-Presse reports (4/10).

12 Apr 2013

Sanofi launches large-scale production of artemisinin for malaria

Twelve years after a breakthrough discovery in his University of California, Berkeley, laboratory, professor of chemical engineering Jay Keasling is seeing his dream come true.

12 Apr 2013

Antipsychotics seemed to normalize gene expression pattern in people with bipolar disorder: Study

Every day, millions of people with bipolar disorder take medicines that help keep them from swinging into manic or depressed moods.

12 Apr 2013

UT MD Anderson scientist receives AACR-CRI Lloyd J. Old Award in Cancer Immunology

The scientist whose discoveries led to the first drug approved for metastatic melanoma by "treating the immune system, not the cancer," also is the first to receive the AACR-CRI Lloyd J. Old Award in Cancer Immunology.

12 Apr 2013

South Africa announces rollout of new single-dose ARV therapy

"South Africa's Health Minister Aaron Motsoaledi announced on Monday the launch of a new single-dose combination antiretroviral drug that will cost just 89 rand a month ($10) per patient, potentially revolutionizing AIDS treatment in the country," Salon reports (McDonough, 4/9).

11 Apr 2013

FDA accepts Merck's NDA for NOXAFIL tablets

Merck, known as MSD outside the United States and Canada, today announced that its New Drug Application for an investigational, tablet formulation of the company's antifungal agent, NOXAFIL (posaconazole), has been accepted for review by the U.S. Food and Drug Administration.

11 Apr 2013

Pfizer's breast cancer compound wins FDA's Breakthrough Therapy designation

Pfizer Inc. announced today its investigational compound palbociclib (PD-0332991), an oral and selective inhibitor of cyclin dependent kinases (CDK) 4 and 6, has received Breakthrough Therapy designation by the United States Food and Drug Administration for the potential treatment of patients with breast cancer.

From Pfizer, Inc. 11 Apr 2013

Research opens new avenue for treatment of melanoma

For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin cancer.

11 Apr 2013

Doctors don't receive information about harmful effects of medicines during promotional visits

The majority of family doctors receive little or no information about harmful effects of medicines when visited by drug company representatives, according to an international study involving Canadian, U.S. and French physicians.

11 Apr 2013

Scientists demonstrate feasibility of using already-approved drugs against pathogens

In the most extensive screen of its kind, Texas Biomed scientists in San Antonio have demonstrated the feasibility of repurposing already-approved drugs for use against highly pathogenic bacteria and viruses.

11 Apr 2013

Coenzyme Q10 offsets cellular changes that are linked to side-effect of some statin drugs: Study

A laboratory study has shown for the first time that coenzyme Q10 offsets the cellular changes that are linked to a side-effect of some statin drugs - an increased risk of adult-onset diabetes.

11 Apr 2013

Five Japanese drug makers form PPP to accelerate development of drugs, vaccines for infectious diseases

"Five Japanese pharmaceutical giants are teaming up with the Bill & Melinda Gates Foundation and Japan's government to develop new medicines, vaccines, and diagnostics for infectious diseases in developing countries," GENNews reports (4/8).

10 Apr 2013

New chemotherapy regimen appears to produce minimal side effects in lung cancer patients

A new chemotherapy regimen appears to produce minimal side effects in patients with lung cancer that has not responded to previous therapy, paving the way for additional research to determine if the new regimen also helps shrink tumors, according findings to be presented by Fox Chase Cancer Center researchers at the AACR Annual Meeting 2013 on Tuesday, April 9.

10 Apr 2013

New study shows combination therapy is effective in treating sarcoma tumors

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors.

10 Apr 2013

Tumors with excess copies of MYCN highly sensitive to BET bromodomain inhibitors, researchers find

An irregularity within many neuroblastoma cells may indicate whether a neuroblastoma tumor, a difficult-to-treat, early childhood cancer, is vulnerable to a new class of anti-cancer drugs known as BET bromodomain inhibitors, Dana-Farber/Children's Hospital Cancer Center scientists will report at the annual meeting of the American Association for Cancer Research in Washington, April 6-10.

10 Apr 2013

Research shows UNC1062 blocks Mer survival signaling in melanoma cells

Collaborative research presented by the University of Colorado Cancer Center, the University of North Carolina at Chapel Hill, Harvard Medical School and the University of Pittsburgh, at the American Association for Cancer Research Annual Conference, shows that the protein receptor Mer is overexpressed in melanoma and that the investigational drug UNC1062 blocks Mer survival signaling in these cells, killing them.

10 Apr 2013

New research shows promise in creating chemical reactions necessary for pharmaceutical companies

Shaken, not stirred, is the essence of new research that's showing promise in creating the chemical reactions necessary for industries such as pharmaceutical companies, but eliminating the resulting waste from traditional methods.

10 Apr 2013

Pharmaceutical News

New research shows effects of long-term use of opioid therapy

U.S., Chinese researchers developing vaccine for H7N9 avian flu virus; Some question speed of case reporting

Nalmefene can provide important clinical benefit for alcohol-dependent patients

New process to create malaria drug artemisinin should provide stable supply, reduce cost, researchers report

Sanofi launches large-scale production of artemisinin for malaria

Antipsychotics seemed to normalize gene expression pattern in people with bipolar disorder: Study

UT MD Anderson scientist receives AACR-CRI Lloyd J. Old Award in Cancer Immunology

South Africa announces rollout of new single-dose ARV therapy

FDA accepts Merck's NDA for NOXAFIL tablets

Pfizer's breast cancer compound wins FDA's Breakthrough Therapy designation

Research opens new avenue for treatment of melanoma

Doctors don't receive information about harmful effects of medicines during promotional visits

Scientists demonstrate feasibility of using already-approved drugs against pathogens

Coenzyme Q10 offsets cellular changes that are linked to side-effect of some statin drugs: Study

Five Japanese drug makers form PPP to accelerate development of drugs, vaccines for infectious diseases

New chemotherapy regimen appears to produce minimal side effects in lung cancer patients

New study shows combination therapy is effective in treating sarcoma tumors

Tumors with excess copies of MYCN highly sensitive to BET bromodomain inhibitors, researchers find

Research shows UNC1062 blocks Mer survival signaling in melanoma cells

New research shows promise in creating chemical reactions necessary for pharmaceutical companies

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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