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New evidence reveals possibility of mood-enhancing effects associated with some flavors

New evidence reveals the possibility of mood-enhancing effects associated with some flavors, stemming at least in part from natural ingredients bearing a striking chemical similarity to valproic acid, a widely used prescription mood-stabilizing drug, scientists reported here today. This effect joins those previously reported for chocolate, teas and some other known comfort foods.

20 Aug 2012

Study demonstrates how Elesclomol blocks oxidative phosphorylation in melanoma

A laboratory study led by UNC medical oncologist Stergios Moschos, MD, demonstrates how a new targeted drug, Elesclomol, blocks oxidative phosphorylation, which appears to play essential role in melanoma that has not been well-understood. Elesclomol (Synta Pharmaceuticals, Lexington, MA) was previously shown to have clinical benefit only in patients with normal serum lactate dehydrogenase (LDH), a laboratory test routinely used to assess activity of disease.

18 Aug 2012

Teva launches generic ACTOplus met to improve glucose control in adults with type 2 diabetes

Teva Pharmaceutical Industries Ltd. announced today the launch of an authorized generic of ACTOplus met (pioglitazone/metformin tablets)15 mg/500 mg, 15 mg/850 mg.

18 Aug 2012

Mylan Pharmaceuticals receives FDA approval for pioglitazone tablets to treat type 2 diabetes

The U.S. Food and Drug Administration today approved the first generic version of Actos (pioglitazone hydrochloride) tablets. Along with diet and exercise, pioglitazone is used to improve blood glucose control in adults with type 2 diabetes.

18 Aug 2012

Lilly, Boehringer Ingelheim receive FDA approval for Tradjenta sNDA to treat type 2 diabetes

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announced the U.S. Food and Drug Administration (FDA) has approved a supplemental new drug application (sNDA) for Tradjenta (linagliptin) tablets for use as add-on therapy to insulin.

18 Aug 2012

Ranbaxy’s generic pioglitazone hydrochloride tablets now available in the U.S.

Ranbaxy Pharmaceuticals Inc., a wholly owned subsidiary of Ranbaxy Laboratories Ltd. (RLL), has launched authorized generic pioglitazone hydrochloride tablets in the U.S. market, under an agreement with Takeda Pharmaceuticals U.S.A., Inc.

17 Aug 2012

Electronic PMP use may have impact on demand for drug treatment programs, painkiller abuse

A Rhode Island Hospital researcher has found that the use of electronic prescription drug monitoring programs (PMPs) may have a significant impact on the demand for drug treatment programs and how prescribers detect and respond to abuse of painkillers.

17 Aug 2012

Blog examines use of controversial HIV drug in Malawi

This post in the Center for Global Health Policy's "Science Speaks" blog examines the use of stavudine, "also known as d4T, an antiretroviral treatment that was dropped in wealthy countries years ago and that the World Health Organization has recommended stop being included in treatment programs," to treat HIV in Malawi.

17 Aug 2012

Study examines whether eribulin offers added benefit to women with breast cancer

Eribulin was approved in March 2011 for women with locally advanced or metastasizing breast cancer in whom the disease has progressed despite prior drug therapy.

17 Aug 2012

ACOEM integrates U.S. FDA's National Drug Code data into APG-I

The American College of Occupational and Environmental Medicine (ACOEM) has integrated the U.S. Federal Drug Administration's National Drug Code (NDC) data into APG-I, the College's on-line Occupational Medicine Practice Guidelines data base.

17 Aug 2012

Blog examines administration of zinc, rehydration salts to treat diarrhea in rural India

In this post in the PLoS "Speaking of Medicine" blog, guest blogger Oliver Sabot, executive vice president of the Clinton Health Access Initiative, "reflects on the challenge and opportunity of scaling-up access to effective treatment for diarrhea, the second largest cause of child mortality globally."

17 Aug 2012

Study finds genetically modified rice good source of vitamin A for malnourished children

"Genetically modified rice could be a good source of vitamin A for children in countries where deficiency in the vitamin is common," according to a new study published in the American Journal of Clinical Nutrition, Reuters reports.

17 Aug 2012

Peptide combinations might offer more effective cancer therapy

Two studies suggest that two peptide agents used either together or individually with a low-dose of a standard chemotherapy drug might offer more effective cancer therapy than current standard single-drug treatments.

17 Aug 2012

Curcumin shows promise in fighting devastating viruses

The popular spice turmeric packs more than just flavor - it shows promise in fighting devastating viruses, Mason researchers recently discovered.

17 Aug 2012

Vancomycin may not always be the best choice for treatment of bloodstream infections

The antibiotic most commonly prescribed to treat bloodstream infections in dialysis patients may not always be the best choice, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

17 Aug 2012

Nostrum, VCU sign license agreement to develop inhaled dapsone for respiratory diseases

Virginia Commonwealth University and Nostrum Pharmaceuticals, LLC, are pleased to announce the signing of a license agreement for the development of inhaled dapsone for the treatment of respiratory diseases.

17 Aug 2012

Researchers use small molecule compound to generate reversible birth control in male mice

The development of a male contraceptive pill has long proven to be elusive, but findings from a new study may point scientists in the right direction to making oral birth control for men a reality.

17 Aug 2012

U.S. FDA warns of post-surgery codeine deaths in children

The U.S. Food and Drug Administration today issued a Drug Safety Communication concerning three children who died and one child who experienced a non-fatal but life-threatening case of respiratory depression after taking the pain reliever codeine following surgery to remove tonsils (tonsillectomy) and/or adenoids (adenoidectomy).

16 Aug 2012

Researchers discover mechanisms responsible for chemoresistance in ovarian cancer

The presence of multiple ovarian cancer genomes in an individual patient and the absence or downregulation of the gene LRP1B are associated with the development of chemoresistance in women with the high-grade serous cancer subtype of ovarian cancer whose disease recurs after primary treatment. These study results are published in Cancer Research, a journal of the American Association for Cancer Research.

16 Aug 2012

Combination of Zelboraf and immunotherapy increases tumor responses and survival in MM

Combining the recently approved BRAF inhibitor, Zelboraf with an engineered T cell immunotherapy to treat metastatic melanoma significantly increased tumor responses and survival in an animal model, researchers at UCLA's Jonsson Comprehensive Cancer Center have shown.

16 Aug 2012

Pharmaceutical News

New evidence reveals possibility of mood-enhancing effects associated with some flavors

Study demonstrates how Elesclomol blocks oxidative phosphorylation in melanoma

Teva launches generic ACTOplus met to improve glucose control in adults with type 2 diabetes

Mylan Pharmaceuticals receives FDA approval for pioglitazone tablets to treat type 2 diabetes

Lilly, Boehringer Ingelheim receive FDA approval for Tradjenta sNDA to treat type 2 diabetes

Ranbaxy’s generic pioglitazone hydrochloride tablets now available in the U.S.

Electronic PMP use may have impact on demand for drug treatment programs, painkiller abuse

Blog examines use of controversial HIV drug in Malawi

Study examines whether eribulin offers added benefit to women with breast cancer

ACOEM integrates U.S. FDA's National Drug Code data into APG-I

Blog examines administration of zinc, rehydration salts to treat diarrhea in rural India

Study finds genetically modified rice good source of vitamin A for malnourished children

Peptide combinations might offer more effective cancer therapy

Curcumin shows promise in fighting devastating viruses

Vancomycin may not always be the best choice for treatment of bloodstream infections

Nostrum, VCU sign license agreement to develop inhaled dapsone for respiratory diseases

Researchers use small molecule compound to generate reversible birth control in male mice

U.S. FDA warns of post-surgery codeine deaths in children

Researchers discover mechanisms responsible for chemoresistance in ovarian cancer

Combination of Zelboraf and immunotherapy increases tumor responses and survival in MM

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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