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Researchers use mouse model of autism to treat CTD

Using a mouse model of autism, researchers at the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center have successfully treated an autism spectrum disorder characterized by severe cognitive impairment.

3 Jul 2012

IRIN examines antibiotic resistance, efforts to discover new drugs

IRIN examines a global increase in resistance to antibiotics, writing, "Almost one in every five deaths worldwide occurs as a result of infection, but many bacterial illnesses will become incurable as the efficacy of current antibiotic drugs wanes, according to the World Health Organization (WHO)."

3 Jul 2012

Study shows link between changing rates of antibiotic consumption and resistance

A new study published in Clinical Infectious Diseases and available online shows how seasonal changes in outpatient antibiotic use - retail sales of antibiotics typically get a boost during the winter - can significantly alter seasonal patterns of drug resistance. The findings suggest that hospital campaigns to reduce inappropriate antibiotic use should be coordinated with efforts in the broader community if they are to be most effective.

3 Jul 2012

GRP78 plays an important role in breast cancers that respond to anti-estrogen therapy

Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.

3 Jul 2012

GHB binds to GABAA-receptor in the brain under physiologically relevant conditions

Researchers are closer to understanding the biology behind GHB, a transmitter substance in the brain, best known in its synthetic form as the illegal drug fantasy. These findings have just been published in the scientific journal PNAS.

3 Jul 2012

$Researchers report positive effects of ibuprofen on bone repair after fracture or surgery$

Researchers report positive effects of ibuprofen on bone repair after fracture or surgery

A study conducted at the University of Granada has demonstrated that ibuprofen -a non-steroidal anti-inflammatory drug (NSAID)- has beneficial effects on bone repair after a fracture or following bone surgery.

3 Jul 2012

FDA accepts BLA filing and grants Priority Review to ThromboGenics' ocriplasmin

ThromboGenics NV, a biopharmaceutical company focused on developing innovative ophthalmic medicines, today announced that the U.S. Food and Drug Administration (FDA) has informed the Company that it has officially accepted the filing of the Biologics License Application for ocriplasmin intravitreal injection, 2.5 mg/ml and granted it Priority Review.

3 Jul 2012

Study provides evidence for meth abuse's causal effect on foster home admissions

Methamphetamine abuse leads to an increase in child abuse and neglect, which causes an increase in foster care admissions, according to a study from Baylor University.

3 Jul 2012

Study demonstrates effectiveness of combination therapy for breast cancer cells in vitro

A study conducted at Boston University School of Medicine (BUSM) demonstrates an effective combination therapy for breast cancer cells in vitro.

3 Jul 2012

Researchers show how aggressive form of multiple myeloma resists chemotherapy

Researchers at Washington University School of Medicine in St. Louis have shown how an aggressive form of multiple myeloma resists chemotherapy.

3 Jul 2012

USPTO issues notice of allowance to Avanir for NUEDEXTA

Avanir Pharmaceuticals, Inc. announced today that the United States Patent and Trademark Office (USPTO) has allowed a new patent that covers Avanir's product NUEDEXTA, further expanding the intellectual property portfolio for the company's lead commercial asset.

2 Jul 2012

Blocking AXL protein may prevent resistance to lung cancer drug

People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will return—it's a question of when. And for far too many, it happens far too soon.

2 Jul 2012

New study lessens concerns about dengue vaccine production costs

"Research funded by the Dengue Vaccine Initiative (DVI) involving an economic analysis of producing a tetravalent dengue vaccine shows that the cost could be as low as $0.20 per dose with an annual production level of 60 million doses packaged in 10-dose vials," a Sabin Vaccine Institute press release reports.

30 Jun 2012

Smokers with COPD may find relief with cystic fibrosis drug

A drug developed to treat certain strains of cystic fibrosis may be useful in the treatment of chronic obstructive pulmonary disease, one of the most common lung diseases, which is seen frequently in smokers and has no cure. The findings were published online Friday, June 29, 2012 in the online journal PLoS ONE by researchers at the University of Alabama at Birmingham.

30 Jun 2012

Noven Pharmaceuticals provides update on status of generic Lidoderm ANDA

Noven Pharmaceuticals, Inc. today provided an update on the status of its pending Abbreviated New Drug Application (ANDA) seeking approval to market a lidocaine topical patch 5%. Noven's lidocaine topical patch 5% is a generic version of Endo Pharmaceuticals' Lidoderm.

30 Jun 2012

Injections of corticoid preparations can have severe side effects

Injections of corticoid preparations can have severe side effects. In this issue of Deutsches Ärzteblatt International, Christian Holland and coauthors contribute to physicians' awareness of problems of this type with a report on the relevant findings of medicolegal expert committees in Germany.

29 Jun 2012

$Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs$

Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs

New research has shed light on the high risk of fractures, falls, and osteoporosis among epilepsy patients using antiepileptic drugs (AEDs) with most patients unaware of the risks associated with taking the drugs.

29 Jun 2012

Inhibiting immune response during initial multi-drug therapy could speed TB treatment time

Inhibiting a key immune response in mice during initial multi-drug treatment for tuberculosis could - paradoxically - shorten treatment time for the highly contagious lung infection according to new research from Johns Hopkins Children's Center and the Center for TB Research.

29 Jun 2012

Cost of dengue vaccine production could be as low as $0.20 per dose

Research funded by the Dengue Vaccine Initiative (DVI) involving an economic analysis of producing a tetravalent dengue vaccine shows that the cost could be as low as $0.20 per dose with an annual production level of 60 million doses packaged in ten-dose vials. The study used data on a vaccine developed by US NIH and the facilities of the Instituto Butantan in Sao Paulo, Brazil.

29 Jun 2012

Study explains why memory improves on a high-DHA diet

We've all heard that eating fish is good for our brains and memory. But what is it about DHA, an omega-3 fatty acid found in fish, that makes our memory sharper? Medical researchers at the University of Alberta discovered a possible explanation and just published their findings in the peer-reviewed journal Applied Physiology, Nutrition, and Metabolism.

29 Jun 2012

Pharmaceutical News

Researchers use mouse model of autism to treat CTD

IRIN examines antibiotic resistance, efforts to discover new drugs

Study shows link between changing rates of antibiotic consumption and resistance

GRP78 plays an important role in breast cancers that respond to anti-estrogen therapy

GHB binds to GABAA-receptor in the brain under physiologically relevant conditions

Researchers report positive effects of ibuprofen on bone repair after fracture or surgery

FDA accepts BLA filing and grants Priority Review to ThromboGenics' ocriplasmin

Study provides evidence for meth abuse's causal effect on foster home admissions

Study demonstrates effectiveness of combination therapy for breast cancer cells in vitro

Researchers show how aggressive form of multiple myeloma resists chemotherapy

USPTO issues notice of allowance to Avanir for NUEDEXTA

Blocking AXL protein may prevent resistance to lung cancer drug

New study lessens concerns about dengue vaccine production costs

Smokers with COPD may find relief with cystic fibrosis drug

Noven Pharmaceuticals provides update on status of generic Lidoderm ANDA

Injections of corticoid preparations can have severe side effects

Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs

Inhibiting immune response during initial multi-drug therapy could speed TB treatment time

Cost of dengue vaccine production could be as low as $0.20 per dose

Study explains why memory improves on a high-DHA diet

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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