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Research brief describes enrollment of first patient with TRK fusion cancer in LOXO-101 Phase 1 trial

The University of Colorado Cancer Center and Loxo Oncology, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of targeted cancer therapies, today announced the publication of a research brief in the online edition of the journal Cancer Discovery, describing the first patient with a tropomyosin receptor kinase (TRK) fusion cancer enrolled in the Phase 1 dose escalation trial of LOXO-101, the only selective TRK inhibitor in clinical development.

28 Jul 2015

Lidocaine benefits breast cancer survivors who experience pain during intercourse

Scientists at Oregon Health & Science University report that breast cancer survivors who experience pain during sexual intercourse, a common side effect of breast cancer treatment, may achieve comfort when liquid lidocaine is applied strategically to prevent pain.

28 Jul 2015

CRINONE (progesterone gel) approved in nine new EU countries

Juniper Pharmaceuticals, Inc., a women's health specialty pharmaceutical company, today announced that the regulatory bodies of nine new European Union (EU) countries, including Poland and France, have granted marketing authorization to CRINONE (progesterone gel) under the mutual-recognition procedure (MRP).

28 Jul 2015

RGS2 protein plays significant role in healthy egg-sperm union in mice

Researchers at the National Institutes of Health have discovered a protein that plays a vital role in healthy egg-sperm union in mice. The protein RGS2 can delay an egg's development into an embryo in order to allow time for sperm to arrive and merge with the egg in a healthy fertilization process. The embryo cannot survive without the male chromosomes.

28 Jul 2015

Study shows that home births lead to higher infant mortality among Dutch women living in poorer areas

Home births lead to higher infant mortality than hospital births, at least for mothers living in poorer areas. This is the conclusion of a new study conducted by N. Meltem Daysal (University of Southern Denmark and IZA), Mircea Trandafir (University of Southern Denmark and IZA) and Reyn van Ewijk (VU University Amsterdam and University of Mainz) that examines 356,412 low-risk Dutch women who delivered between 2000 and 2008 and who were allowed to choose between a home and a hospital birth.

28 Jul 2015

Increased awareness of fertility preservation options needed for young patients with cancer

A new study points to the need for increased awareness of fertility preservation options for young patients with cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study found that factors such as gender, education, and insurance status may impact whether patients and their physicians have discussions and take actions to preserve fertility during cancer treatment.

28 Jul 2015

Researchers find blood marker that can help identify women at particular risk for postpartum depression

Postpartum depression is a debilitating disorder that affects nearly 20 percent of new mothers, putting their infants at increased risk for poor behavioral, cognitive and social development.

28 Jul 2015

Protein imbalances within cells can cause ovarian cancer

Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found. The discovery is a major breakthrough because, until now, genetic aberrations have been seen as the main cause of almost all cancer.

28 Jul 2015

Study reveals impact of patient navigator program on no-show rates for cervical cancer screening

Researchers at Harvard Medical School and Brigham and Women's Hospital reported a 20% decline in the rate of missed appointments for cervical cancer evaluation following a Pap smear when a patient navigator program was initiated at the referral center.

25 Jul 2015

WSU scientists suggest that glyphosate not present in human breast milk

Washington State University scientists have found that glyphosate, the main ingredient in the herbicide Roundup, does not accumulate in mother's breast milk.

24 Jul 2015

Brown University explores effect of chemical exposures on the brain and thyroid during pregnancy, childhood

Exposure to the endocrine disrupting chemicals bisphenol A, triclosan and phthalates is ubiquitous in the United States, raising concerns that they may affect health. With a new four-year, $1.5 million grant from the National Institutes of Health, Brown University epidemiologist Joseph Braun will try to close a gap in research: the effect of these exposures on the brain and thyroid during pregnancy and childhood.

24 Jul 2015

Researchers discover experimental drug that treats hot flashes, other menopausal symptoms without side effects

Researchers have discovered an experimental medication that treats hot flashes and other menopausal symptoms without the life-threatening risks of hormone replacement therapy, according to a team led by a UNT Health Science Center scientist.

23 Jul 2015

New survey explores US women's sexual risk-taking as tourists

Relaxing beach vacations are perfect for sexual experimentation with a steady partner, while group tours and sightseeing trips are the ultimate contexts for casual sex with acquaintances or strangers, women said in a new survey.

23 Jul 2015

Additional radiation to surrounding lymph nodes provides added benefit to breast cancer patients

A study has found no increase in overall survival but a reduction in breast cancer recurrence when additional radiation is given to the lymph nodes as well as the standard treatment of whole-breast irradiation after breast-conserving surgery.

23 Jul 2015

Study finds that serum biomarkers can predict pre-eclampsia risk in pregnant women

Levels of biomarkers in the blood of pregnant women can be used to predict which women are at risk of pre-eclampsia, finds a study published today (22 July) in BJOG: An International Journal of Obstetrics and Gynaecology (BJOG). ADMA and Hcy, both known to be raised in women with pre-eclampsia, are present in the blood in higher than normal concentrations a month before the onset of the condition.

23 Jul 2015

Important new target identified for ovarian cancer therapy

Scientists at Lawson Health Research Institute have uncovered an important new target for ovarian cancer therapy. Contrary to current research this new study found that LKB1, a molecule that regulates the metabolism of many adult cells, is an important molecule in the cancer's promotion and survival.

23 Jul 2015

Late- and post-menopausal women have more fat around hearts compared to pre-menopausal counterparts

Late- and post-menopausal women have significantly greater volumes of fat around their hearts - a risk factor for heart disease - than their pre-menopausal counterparts, a University of Pittsburgh Graduate School of Public Health study has shown for the first time.

23 Jul 2015

Screening for HIV in pregnancy eliminates vertical transmission

Canada has almost eliminated mother-to-child HIV transmission, known as vertical transmission, in recent years by ensuring that all women have the opportunity to be screened for HIV in pregnancy and that women with the disease receive treatment before giving birth.

23 Jul 2015

Study: Cash to stay in school did not reduce HIV risk among young women in South Africa

A Phase III, individually randomized trial has found conditional cash transfers for school attendance did not reduce the risk of HIV among high-school aged women in South Africa, investigators from the HIV Prevention Trials Network (HPTN) reported today at the 8th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention in Vancouver, Canada.

22 Jul 2015

PolyU researchers create comprehensive breast milk nutrient database in Hong Kong

Breastfeeding has become more common all across the world in recent years, however, breastfeeding rate has remained low in Hong Kong. One of the main reasons is that Hong Kong mothers worry about the nutrient adequacy of their breast milk to meet the growing needs of the infant.

22 Jul 2015

Women's Health News

Research brief describes enrollment of first patient with TRK fusion cancer in LOXO-101 Phase 1 trial

Lidocaine benefits breast cancer survivors who experience pain during intercourse

CRINONE (progesterone gel) approved in nine new EU countries

RGS2 protein plays significant role in healthy egg-sperm union in mice

Study shows that home births lead to higher infant mortality among Dutch women living in poorer areas

Increased awareness of fertility preservation options needed for young patients with cancer

Researchers find blood marker that can help identify women at particular risk for postpartum depression

Protein imbalances within cells can cause ovarian cancer

Study reveals impact of patient navigator program on no-show rates for cervical cancer screening

WSU scientists suggest that glyphosate not present in human breast milk

Brown University explores effect of chemical exposures on the brain and thyroid during pregnancy, childhood

Researchers discover experimental drug that treats hot flashes, other menopausal symptoms without side effects

New survey explores US women's sexual risk-taking as tourists

Additional radiation to surrounding lymph nodes provides added benefit to breast cancer patients

Study finds that serum biomarkers can predict pre-eclampsia risk in pregnant women

Important new target identified for ovarian cancer therapy

Late- and post-menopausal women have more fat around hearts compared to pre-menopausal counterparts

Screening for HIV in pregnancy eliminates vertical transmission

Study: Cash to stay in school did not reduce HIV risk among young women in South Africa

PolyU researchers create comprehensive breast milk nutrient database in Hong Kong

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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