Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study links high and low levels of "good" cholesterol with dementia risk

Having either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increased risk of dementia in older adults, according to a study published in the October 4, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 Oct 2023

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Researchers developed the ATRIVIEW® platform to screen for molecules that promote differentiation neural stem cells (NSCs).

4 Oct 2023

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

Researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2).

4 Oct 2023

Walking and Mediterranean diet may be the ticket to reducing dementia risk

The study explores the MedWalk intervention, promoting a Mediterranean-style diet and regular walking, to potentially slow cognitive decline in older adults without existing impairments. Despite COVID-19 disruptions, progress with 157 participants suggests this approach, rooted in psychosocial techniques, could offer a lifestyle-based deterrent against dementia and cognitive deterioration.

4 Oct 2023

Study addresses possible associations between chronic stress, mild cognitive impairment and Alzheimer's

Researchers from Karolinska Institutet have published a study in Alzheimer's Research & Therapy that addresses possible associations between chronic stress, mild cognitive impairment and Alzheimer's disease.

3 Oct 2023

Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

Novel deep learning model to assess Alzheimer's disease progression risk

Patterns in the Alzheimer's disease (AD) trajectory using Mendelian randomization (MR) and deep learning (DL).

3 Oct 2023

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).

3 Oct 2023

How lifestyle tweaks could be the new shield against memory loss: U.S. POINTER study dives in

The U.S. POINTER study aims to explore if lifestyle changes like exercise, diet, and social activities can help preserve cognitive function in older Americans at risk for dementia. Modeled after Finland's successful FINGER study and set to complete in 2025, this extensive research will involve 2,000 participants and focus on diverse and culturally informed strategies.

2 Oct 2023

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

A new tau PET radiotracer, 18F-SNFT-1, has been found to be more effective than existing tau PET radiotracers in identifying Alzheimer's disease in its earliest stages, according to research published in the September issue of The Journal of Nuclear Medicine.

29 Sep 2023

Insights and new directions in basic, clinical research into neurodegenerative diseases

A special supplement to the Journal of Alzheimer's Disease, published by IOS Press, presents insights and new directions in both basic and clinical research into neurodegenerative diseases.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

More pregnancies and longer reproductive lifespan may protect against cerebral small vessel disease

People with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, according to a new study published in the September 27, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

27 Sep 2023

Short-term exposure to air pollution may increase stroke risk

Short-term exposure to air pollution may be linked to an increased risk of stroke, according to a meta-analysis published in the September 27, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology. Short-term exposure was defined as occurring within five days of the stroke.

27 Sep 2023

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

Researchers utilize imaging findings to elucidate how Alzheimer's dementia can present considerable variations depending on the sex of the individual.

27 Sep 2023

SwRI and UTSA develop breath analysis techniques to detect TBI

Researchers from Southwest Research Institute (SwRI) and The University of Texas at San Antonio (UTSA) are developing techniques to detect traumatic brain injury (TBI) by analyzing breath for specific biomarkers.

26 Sep 2023

Traumatic life events may directly increase your risk for dementia

The association between traumatic life events (TLE) and the risk of all-cause dementia.

26 Sep 2023

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Recent research demonstrates that protein phase separation (PPS) is widely present in cells and drives a variety of important biological functions.

25 Sep 2023

Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric diseases.

25 Sep 2023

Finnish study finds revised dementia guidelines did not reduce psychotropic use

A recent register-based study examined the impact of Finland's revised clinical guidelines for the treatment of dementia, published in 2017, on the trend of users of psychotropics in older people with dementia in 2009-2020.

25 Sep 2023

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study links high and low levels of "good" cholesterol with dementia risk

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

Walking and Mediterranean diet may be the ticket to reducing dementia risk

Study addresses possible associations between chronic stress, mild cognitive impairment and Alzheimer's

Microglial states and their impact on Alzheimer's disease

Novel deep learning model to assess Alzheimer's disease progression risk

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

How lifestyle tweaks could be the new shield against memory loss: U.S. POINTER study dives in

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

Insights and new directions in basic, clinical research into neurodegenerative diseases

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

More pregnancies and longer reproductive lifespan may protect against cerebral small vessel disease

Short-term exposure to air pollution may increase stroke risk

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

SwRI and UTSA develop breath analysis techniques to detect TBI

Traumatic life events may directly increase your risk for dementia

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Finnish study finds revised dementia guidelines did not reduce psychotropic use

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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