Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Omeros identifies compounds that interact with orphan GPCRs associated with leukemia

Omeros Corporation today reported that it has identified compounds that interact with orphan G protein-coupled receptors (GPCRs) P2Y8 and OPN4. P2Y8 (also known as P2RY8) is associated with acute lymphoblastic leukemia (ALL), an aggressive cancer of the white blood cells.

27 Jun 2011

EnVivo initiates EVP-0962 GSM Phase 1 clinical trial for Alzheimer’s disease

EnVivo Pharmaceuticals, a company dedicated to developing a broad range of novel central nervous system (CNS) therapies, announced today that it recently initiated a Phase 1 clinical trial of EVP-0962, its potent and selective gamma secretase modulator (GSM), in healthy volunteers.

27 Jun 2011

First Edition: June 27, 2011

Today's headlines include reports about the status of ongoing deficit negotiations and details about a "stealth" survey on access to doctors.

27 Jun 2011

Some HIV drugs can cause premature ageing

A class of anti-retroviral drugs commonly used to treat HIV, particularly in Africa and low income countries, can cause premature ageing, according to research published today in the journal Nature Genetics. The study shows that the drugs damage DNA in the patient's mitochondria - the 'batteries' which power their cells.

27 Jun 2011

Experts discuss global threat of Alzheimer's disease at House subcommittee hearing

"Alzheimer's experts urged U.S. lawmakers on Thursday to increase funding for research of the debilitating disease and to push international policymakers to pay more attention to its global impact," Reuters reports (Steenhuysen, 6/23).

24 Jun 2011

Viewpoints: Sebelius defends IPAB; Wash Post on debt talks and entitlements

A key part of the president's plan, the Independent Payment Advisory Board, has recently been the subject of inaccurate claims. Critics say it will ration care and put bureaucrats in charge of the health care system.

24 Jun 2011

Department of Defense awards Impel Phase II SBIR grant for blood-brain barrier bypass technology

Impel NeuroPharma, a medical device company whose technology is designed to enable pharmaceutical drugs to bypass the blood-brain barrier and enter the central nervous system (CNS), today announced that it was selected to receive a Phase II Small Business Investigational Research (SBIR) grant from the Department of Defense's Chemical and Biological Defense SBIR Program entitled, "Blood Brain Barrier Drug Delivery of Therapeutics for Chemical Warfare Agents."

24 Jun 2011

Scientists gain insight into how brains process memory and sense of orientation

How do our brains process memory and sense of orientation? Scientists are gaining insight by studying rats with implanted genes that prompt neurons to fire on command.

24 Jun 2011

Combined pediatric neuroscience programs at Barrow Neurological Institute

St. Joseph's Hospital and Medical Center and Phoenix Children's Hospital jointly announced this week their pediatric neuroscience programs are combining under the newly formed Barrow Neurological Institute at Phoenix Children's Hospital.

24 Jun 2011

Scientists uncover new therapeutic target for Huntington's disease

UT Southwestern Medical Center researchers have identified compounds that appear to inhibit a signaling pathway in Huntington's disease, a finding that may eventually lead to a potential drug therapy to help slow the progression of degenerative nerve disorders.

24 Jun 2011

Research offers avenue for creating Alzheimer's and HIV therapeutics

A new advance by UCLA biochemists has brought scientists one step closer to developing treatments that could delay the onset of Alzheimer's disease and prevent the sexual transmission of HIV.

24 Jun 2011

Lithium can prevent aggregation of toxic proteins and cell loss linked with Parkinson's

Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson's disease (PD) in a mouse model of the condition.

24 Jun 2011

Anticholinergic drugs might increase risk of cognitive impairment, death in older people

A side effect of many commonly used drugs appears to increase the risks of both cognitive impairment and death in older people, according to new research led by the University of East Anglia.

24 Jun 2011

Adeona enters agreement to begin proprietary zinc-based therapy Phase IIb trial in ALS

Adeona Pharmaceuticals, Inc., a developer of innovative medicines for serious central nervous system diseases, announced today that it has expanded its pipeline of proprietary zinc-based therapies to include a planned Phase IIb clinical trial of patients suffering from amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease.

24 Jun 2011

Some drug mixtures may be fatal for elderly: study

British scientists warn that well known brands of hay fever tablets, painkillers and sleeping pills pose a previously unknown threat to elderly people’s health when taken together. Many are available over the counter at pharmacies as well as being prescribed by GPs, nurses and chemists they said.

23 Jun 2011

New sAPPβ biomarker may identify people at risk of developing Alzheimer's

A new biomarker may help identify which people with mild memory deficits will go on to develop Alzheimer's disease, according to a new study published in the June 22, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Jun 2011

Unraveling molecular dysfunction due to environmental toxin exposure

In a new article published in the journal Molecular Neurodegeneration, researchers at the University of Missouri School of Medicine take some of the first steps toward unraveling the molecular dysfunction that occurs when proteins are exposed to environmental toxins. Their discovery helps further explain recent NIH findings that demonstrate the link between Parkinson's disease and two particular pesticides - rotenone and paraquat.

23 Jun 2011

New surprising details about flow of neurotransmitters between brain neurons

Two studies featuring research from Weill Cornell Medical College have uncovered surprising details about the complex process that leads to the flow of neurotransmitters between brain neurons -- a dance of chemical messages so delicate that missteps often lead to neurological dysfunction.

23 Jun 2011

Axxam receives ADDF grant to develop new therapeutics for Alzheimer's

The Alzheimer's Drug Discovery Foundation (ADDF) announced today that it has awarded a grant to Axxam SpA to develop small molecules to treat Alzheimer's disease by targeting inflammation.

23 Jun 2011

Singer Glen Campbell diagnosed with Alzheimer’s

Glen Campbell, the American country pop singer, has been diagnosed with Alzheimer's disease. His wife Kim, said she wanted fans to be aware of his condition.

23 Jun 2011

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Omeros identifies compounds that interact with orphan GPCRs associated with leukemia

EnVivo initiates EVP-0962 GSM Phase 1 clinical trial for Alzheimer’s disease

First Edition: June 27, 2011

Some HIV drugs can cause premature ageing

Experts discuss global threat of Alzheimer's disease at House subcommittee hearing

Viewpoints: Sebelius defends IPAB; Wash Post on debt talks and entitlements

Department of Defense awards Impel Phase II SBIR grant for blood-brain barrier bypass technology

Scientists gain insight into how brains process memory and sense of orientation

Combined pediatric neuroscience programs at Barrow Neurological Institute

Scientists uncover new therapeutic target for Huntington's disease

Research offers avenue for creating Alzheimer's and HIV therapeutics

Lithium can prevent aggregation of toxic proteins and cell loss linked with Parkinson's

Anticholinergic drugs might increase risk of cognitive impairment, death in older people

Adeona enters agreement to begin proprietary zinc-based therapy Phase IIb trial in ALS

Some drug mixtures may be fatal for elderly: study

New sAPPβ biomarker may identify people at risk of developing Alzheimer's

Unraveling molecular dysfunction due to environmental toxin exposure

New surprising details about flow of neurotransmitters between brain neurons

Axxam receives ADDF grant to develop new therapeutics for Alzheimer's

Singer Glen Campbell diagnosed with Alzheimer’s

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How innovation in dried blood spot testing is transforming neurological disease monitoring

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How innovation in dried blood spot testing is transforming neurological disease monitoring

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

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